Psychiatry Flashcards
(110 cards)
What are the key features of acute stress disorder?
occurs in first 4 weeks after a traumatic event
intrusive thoughts e.g. flashbacks, nightmares
dissociation e.g. ‘being in a daze’, time slowing
negative mood
avoidance
arousal e.g. hypervigilance, sleep disturbance
What is the management of acute stress disorder?
Trauma-focused CBT
Benzodiazepines
What are the features of alcohol withdrawal?
Symptoms start at 6-12 hours after cessation - tremor, sweating, tachycardia, anxiety
What are the features of delirium tremens?
Coarse tremor, confusion, delusions, auditory and visual hallucinations, fever, tachycardia
When is the peak incidence of seizures following alcohol withdrawal?
36 hours
When is the peak incidence of delirium tremens?
48-72 hours
What is the management of delirium tremens?W
Admit to hospital for monitoring until withdrawals stabilized
Long-acting benzodiazepines (chlordiazepoxide, diazepam, lorazepam if hepatic failure)
What are the features of anorexia nervosa?
reduced body mass index
bradycardia
hypotension
enlarged salivary glands
What physiological abnormalities are present in anorexia nervosa?
hypokalaemia low FSH, LH, oestrogens and testosterone raised cortisol and growth hormone impaired glucose tolerance hypercholesterolaemia hypercarotinaemia low T3
What is the MOA of typical antipsychotics?
Dopamine D2 receptor antagonists, blocking dopaminergic transmission in the mesolimbic pathways
What is the MOA of atypical antipsychotics?
Act on a variety of receptors (D2, D3, D4, 5-HT)
What are the adverse side effects of typical antipsychotics?
Parkinsonism Acute dystonia (torticollis, oculogyric crisis) Akathisia Tardive dyskinesia Hyperprolactinemia Neuroleptic malignant syndrome Reduced seizure threshold Prolonged QT interval Anti-muscarinic
What is the management of acute dystonia?
Procyclidine
What are the features of tardive dyskinesia?
Late onset of choreoathetoid movements, abnormal, involuntary, may occur in 40% of patients, may be irreversible, most common is chewing and pouting of jaw
What does the use of antipsychotics increase the risk of in the elderly?
Stroke
VTE
What are the side effects of atypical antipsychotics?
Weight gain
Agranulocytosis
Hyperprolactinemia
Which atypical antipsychotic is associated with agranulocytosis?
Clozapine
Which atypical antipsychotic is associated with dyslipidemia and obesity?
Olanzapine
How should benzodiazepines be stopped?
Swtich to an equivalent dose of diazepam and reduce the dose every 2-3 weeks in steps of 2 or 2.5mg.
The time for withdrawal can vary from 4 weeks to a year or more.
What are the features of body dysmorphic disorder?
Preoccupation with an imagine defect in appearance. If a slight physical anomaly is present, the person’s concern is markedly excessive
The preoccupation causes clinically significant distress or impairment in social, occupational, or other important areas of functioning
The preoccupation is not better accounted for by another mental disorder (e.g., dissatisfaction with body shape and size in Anorexia Nervosa)
What are the criteria for bulimia nervosa?
Recurrent episodes of binge eating
Sense of lack of control over eating during the episode
Recurrent inappropriate compensatory behavior to prevent weight gain (vomiting, laxative abuse, diuretics, fasting, exercise, etc)
Binge eating and compensatory behaviors occur at least once a week for three months.
What is the management of bulimia nervosa?
Specialist care
CBT-ED
High dose fluoxetine
What are the risk factors for Charles-Bonnet syndrome?
Advanced age Peripheral visual impairment - age related macular degeneration, glaucoma, cataract Social isolation Sensory deprivation Early cognitive impairment
What is Charles-Bonnet syndrome?
persistent or recurrent complex hallucinations (usually visual or auditory), occurring in clear consciousness, usually with a background of visual impairment