Psychiatry and Addiction Medicine Flashcards
(44 cards)
Mental health presentation stats
4-5% of all ED presentation
45% of Australians experience mental disorder in their lifetime
20% in last 12 months
Anxiety most common at 14.4% population
Females > males
Mental health ATS triage categories
ATS 1:
- Definite danger to life (self ot others)
- Severe behavioural disorder with immediate threat of dangerous violence e.g. possession of weapon, extreme agitation
ATS 2:
- Immediate threat to self or others
- Requires physical restraint
- Confused/unable to co-operate
- Hallucinations/delusions/paranoia
ATS 3:
- Possible danger to self or others
- Severe distress
- Moderate agitation
- Ambivalent about treatment
ATS 4:
- No immediate risk to self or others
- Co-operative and able to give coherent history
ATS 5:
- No danger to self or others
- No acute distress or behavioural disturbance
- Able to discuss concerns
Most common medical mimics of psychiatric illness
Stimulant toxicity
Serotonin syndrome
Anticholinergic toxicity
Temporal lobe epilepsy
Encephalitis - particularly limbic
UTI or other sepsis - esp. in elderly
Clues to organic cause of psychiatric presentation
Age of onset
- >40, nearly always organic
Delirium
Lack of concern for nudity
Abnormal vital signs
Visual hallucinations
What situations does the mental health legislation provide for?
- Admission procedures of the mentally ill
- Involuntary admission
- Community treatment orders
- Persons incapable of caring for themselves
- Security admissions
- The rights of the mentally ill
- special treatment procedures
Criteria for involuntary admission (under Mental Health Act [Vic] 1986)
- The person appears to be mentally ill
- The person’s mental illness requires immediate attention
- That attention cannot be given as an outpatient
- The patient should be detained for their health and safety, or the health and safety of others
- The person has refused or is unable to consent to treatment
- The person cannot receive treatment in a less restrictive manner
i.e.
Mentally ill, requiring immediate attention for their own safety, that they cannot or will not consent to and can’t be completed in a less restrictive or outpatient setting
Schedule 1 vs 2
Schedule 1
- Request for admission
- May be completed by any adult
Schedule 2
- Recommendation completed by a legally qualified medical practitioner
- Cannot be same person as schedule 1
- Must be examined by authorised psychiatrist within 24 hours of admission
What documents does involuntary admission require (Vic)
3 documents:
Schedule 1
Schedule 2
Treatment plan
Component of CBT (cognitive behavioural therapy)
Arousal management
Graded exposure
Safety response inhibition
Surrender of safety signals
Cognitive strategies
Mindfulness
Problem-solving training
Acceptance and commitment therapy
Major depressive disorder - epidemiology and diagnostic criteria
Bimodal distribution of onset:
- Early 20s vs 50s
2:1 female:male
Depression in first degree relative risk factor
Symptoms present >=2/52
5 of 9 required:
1. Depressed mood most of the day, every day OR diminished interest in activities (MUST HAVE)
2. Sleep disorder
3. Significant (>5%) unintentional weight loss in 1 month
4. Poor concentration
5. Guilt/worthlessness
6. Psychomotor changes (agitation/retardation)
7. Fatigue
8. Recurrent thoughts of death/SI
9. Physical symptoms that do not respond to treatment e.g. pain
Must lead to distress or functional impairment
Must NOT be direct effect of:
- Substance use
- Medical condition
- Bereavement
50% associated anxiety
- Minor depressive disorder
- 2-4 symptoms of major
- At least 2/52
- 25% progression to major within a year
Medical conditions associated with depression
- Alcohol
- Infections
- HIV- Syphyllis
- Lyme disease
* Endocrine - Hypothyroidism
- Hyperparathyroidism
- Adrenocortical insufficiency
- Cushing’s syndrome
- Exogenous steroids
* Malignancy
* Cerebrovascular disease
- Myocardial infarction
* Vitamin B12 deficiency
* Malnutrition
* Medications
- Methyldopa
- Benzodiazepines
- Propranolol
- Corticosteroids
- Anti-Parkinsonian drugs
- Clonidine- Hydralazine
- Oestrogens
- Progesterone
- Tamoxifen
- Hydralazine
Depression management
Mild
- Supportive or counselling most effective e.g. CBT, behavioural activation, interpersonal psychotherapy
- Evidence for e-health methods
Moderate
- Antidepressants, CBT and psychotherapy all equally effective
- Pharmacotherapy:
- Escitalopram, sertraline, venlafaxine most common first line
- Fluoxetine for childhood and adolescent depression
- Will improve symptoms in approx. 50-70% in 2-4 weeks
- 50-70% of initial non-responders will respond to different agent
Severe
- Antidepressant + CBT
- Anti-psychotic if psychotic features present
- ECT (60-80% effective; maximal effect 3/52) - Raised ICP contra-indication
Self-harm prognosis
5% suicide within 10 years
15% representation within 1 year
Suicide epidemiology
In Aus: 50,000 attempts/ year; 3000 deaths
Lifetime prevalence for attempt:
- 2.5% men, 4.5% women
Men 5x more likely to complete attempt
Deaths male:female 4:1
Major features of suicide risk
* Hopelessness and despair (OR 2.2)
* Thoughts that life is not worth living
* Passive wish to die
* Serious suicidal ideation - 30% (OR 2.7)
* Specific suicide plan - 15%
* Previous suicide attempt - 66%
Lethality factors for suicide
“IPMO”
Intention
Plan
Motivation
Opportunity
Sad person’s index
Mnemonic for assessment of suicide risk
S - Sex M
A - Age >45 or <19
D - Depression or hopelessness
P - Previous attempts
E - EtOH and drug abuse
R - Loss of rationality esp. psychotic features
S - Separated or single
O - Organised plan
N - No social supports
S - Sickness (organic)
- Replaced with “stated future intent” for modified index
0-5 = low risk
6-8 = moderate risk
9-14 = high risk
Bipolar I vs II
Type I
- Mania +/- depression (not necessary)
- May include hypomania
Type II
- Depression + hypomania
- No manic episodes
- More common in females
Manic episode criteria
Distinct period of abnormally and persistently elevated, expansive or irritable mood
>=1 week
3 out of 7:
1. Inflated self-esteem or grandiosity
2. Decreased need for sleep
3. More talkative than usual or pressure to keep talking
4. Flight of ideas
5. Distractibility
6. Increase in goal-directed activity (e.g. work/study/sex)
7. Excessive involvement in pleasurable activities with high potential for painful consequence (e.g. buying sprees, gambling)
Hypomania
- Episodes lasting only days
- No marked functional impairment, psychotic features or hospitalisation
Drug-induced psychosis vs Schizophrenia
Psychosis prognosis
Up to 25% secondary depression
10-15% die by suicide
Worse prognosis
- Early onset
- Social isolation
- Poor compliance
- Lack of insight
- Prominent negative symptoms
Better prognosis
- Acute onset
- Normal pre-morbid personality
- Definite precipitating factor
Schizophrenia DSM V criteria
At least 2 of:
- Delusions
- Hallucinations
- Disorganised speech
- Grossly disorganised or catatonic behaviour
- Negative symptoms incl.:
- Lack of motivation
- Poor self-care
- Blunted affect
- Reduced speech output
- Social withdrawal
- Impaired cognitive functioning common
Lasting >6mo incl. prodrome
- Rapid deterioration in social function suggest another cause
Exclusion of substance use and/or medical cause
Antipsychotic MOA + first and second gen differences
D2 receptor competitive antagonist
- Except aripiprazole (partial agonist)
Second gen = higher 5-HT2 receptor blockade
Antipsychotic adverse effects
Extrapyramidal: acute dystonia, akathia, parkinsonism, tardive dyskinesia
- Lower in second gen
Weight gain - esp. olanz, cloz + quetiapine
Diabetes - esp. olanz + cloz
Hyperprolactinaemia, sexual dysfunction - esp. first gen, risperidone
QTc prolongation - esp. amisulpride, halo, ziprasidone
Sedation
Orthostatic hypotension
Rabbit syndrome: rapid contraction of perioral musculature
- Most common in women, asian decent, middle and old age