Psychiatry and Addiction Medicine Flashcards

(44 cards)

1
Q

Mental health presentation stats

A

4-5% of all ED presentation
45% of Australians experience mental disorder in their lifetime
20% in last 12 months
Anxiety most common at 14.4% population
Females > males

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2
Q

Mental health ATS triage categories

A

ATS 1:
- Definite danger to life (self ot others)
- Severe behavioural disorder with immediate threat of dangerous violence e.g. possession of weapon, extreme agitation

ATS 2:
- Immediate threat to self or others
- Requires physical restraint
- Confused/unable to co-operate
- Hallucinations/delusions/paranoia

ATS 3:
- Possible danger to self or others
- Severe distress
- Moderate agitation
- Ambivalent about treatment

ATS 4:
- No immediate risk to self or others
- Co-operative and able to give coherent history

ATS 5:
- No danger to self or others
- No acute distress or behavioural disturbance
- Able to discuss concerns

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3
Q

Most common medical mimics of psychiatric illness

A

Stimulant toxicity
Serotonin syndrome
Anticholinergic toxicity
Temporal lobe epilepsy
Encephalitis - particularly limbic
UTI or other sepsis - esp. in elderly

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4
Q

Clues to organic cause of psychiatric presentation

A

Age of onset
- >40, nearly always organic
Delirium
Lack of concern for nudity
Abnormal vital signs
Visual hallucinations

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5
Q

What situations does the mental health legislation provide for?

A
  1. Admission procedures of the mentally ill
  2. Involuntary admission
  3. ​Community treatment orders
  4. Persons incapable of caring for themselves
  5. Security admissions
  6. The rights of the mentally ill
  7. special treatment procedures
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6
Q

Criteria for involuntary admission (under Mental Health Act [Vic] 1986)

A
  1. The person appears to be mentally ill
  2. The person’s mental illness requires immediate attention
  3. That attention cannot be given as an outpatient
  4. ​The patient should be detained for their health and safety, or the health and safety of others
  5. The person has refused or is unable to consent to treatment
  6. The person cannot receive treatment in a less restrictive manner

i.e.
Mentally ill, requiring immediate attention for their own safety, that they cannot or will not consent to and can’t be completed in a less restrictive or outpatient setting

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7
Q

Schedule 1 vs 2

A

Schedule 1
- Request for admission
- May be completed by any adult

Schedule 2
- Recommendation completed by a legally qualified medical practitioner
- Cannot be same person as schedule 1
- Must be examined by authorised psychiatrist within 24 hours of admission

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8
Q

What documents does involuntary admission require (Vic)

A

3 documents:
Schedule 1
Schedule 2
Treatment plan

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9
Q

Component of CBT (cognitive behavioural therapy)

A

Arousal management
Graded exposure
Safety response inhibition
Surrender of safety signals
Cognitive strategies
Mindfulness
Problem-solving training
Acceptance and commitment therapy

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10
Q

Major depressive disorder - epidemiology and diagnostic criteria

A

Bimodal distribution of onset:
- Early 20s vs 50s
2:1 female:male
Depression in first degree relative risk factor

Symptoms present >=2/52
5 of 9 required:
1. Depressed mood most of the day, every day OR diminished interest in activities (MUST HAVE)
2. Sleep disorder
3. Significant (>5%) unintentional weight loss in 1 month
4. Poor concentration
5. Guilt/worthlessness
6. Psychomotor changes (agitation/retardation)
7. Fatigue
8. Recurrent thoughts of death/SI
9. Physical symptoms that do not respond to treatment e.g. pain

Must lead to distress or functional impairment
Must NOT be direct effect of:
- Substance use
- Medical condition
- Bereavement

50% associated anxiety

  • Minor depressive disorder
  • 2-4 symptoms of major
  • At least 2/52
  • 25% progression to major within a year
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11
Q

Medical conditions associated with depression

A
  • Alcohol
  • Infections
    -​ HIV
    • Syphyllis
    • ​Lyme disease
      *​ Endocrine
    • ​Hypothyroidism
      -​ Hyperparathyroidism
      -​ Adrenocortical insufficiency
      -​ Cushing’s syndrome
      -​ Exogenous steroids
      *​ Malignancy
      *​ Cerebrovascular disease
  • Myocardial infarction
    *​ Vitamin B12 deficiency
    *​ Malnutrition
    *​ Medications
    -​ Methyldopa
    -​ Benzodiazepines
    -​ Propranolol
    -​ Corticosteroids
    -​ Anti-Parkinsonian drugs
    -​ Clonidine
    • ​Hydralazine
      -​ Oestrogens
      -​ Progesterone
      -​ Tamoxifen
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12
Q

Depression management

A

Mild
- Supportive or counselling most effective e.g. CBT, behavioural activation, interpersonal psychotherapy
- Evidence for e-health methods

Moderate
- Antidepressants, CBT and psychotherapy all equally effective
- Pharmacotherapy:
- Escitalopram, sertraline, venlafaxine most common first line
- Fluoxetine for childhood and adolescent depression
- Will improve symptoms in approx. 50-70% in 2-4 weeks
- 50-70% of initial non-responders will respond to different agent

Severe
- Antidepressant + CBT
- Anti-psychotic if psychotic features present
- ECT (60-80% effective; maximal effect 3/52) - Raised ICP contra-indication

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13
Q

Self-harm prognosis

A

5% suicide within 10 years
15% representation within 1 year

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14
Q

Suicide epidemiology

A

In Aus: 50,000 attempts/ year; 3000 deaths
Lifetime prevalence for attempt:
- 2.5% men, 4.5% women
Men 5x more likely to complete attempt
Deaths male:female 4:1

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15
Q

Major features of suicide risk

A

*​ Hopelessness and despair (OR 2.2)
* ​Thoughts that life is not worth living
* ​Passive wish to die
*​ Serious suicidal ideation - 30% (OR 2.7)
*​ Specific suicide plan - 15%
*​ Previous suicide attempt - 66%

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16
Q

Lethality factors for suicide

A

“IPMO”
Intention
Plan
Motivation
Opportunity

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17
Q

Sad person’s index

A

Mnemonic for assessment of suicide risk

S - Sex M
A - Age >45 or <19
D - Depression or hopelessness
P - Previous attempts
E - EtOH and drug abuse
R - Loss of rationality esp. psychotic features
S - Separated or single
O - Organised plan
N - No social supports
S - Sickness (organic)
- Replaced with “stated future intent” for modified index

0-5 = low risk
6-8 = moderate risk
9-14 = high risk

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18
Q

Bipolar I vs II

A

Type I
- Mania +/- depression (not necessary)
- May include hypomania

Type II
- Depression + hypomania
- No manic episodes
- More common in females

19
Q

Manic episode criteria

A

Distinct period of abnormally and persistently elevated, expansive or irritable mood
>=1 week

3 out of 7:
1. Inflated self-esteem or grandiosity
2. Decreased need for sleep
3. More talkative than usual or pressure to keep talking
4. Flight of ideas
5. Distractibility
6. Increase in goal-directed activity (e.g. work/study/sex)
7. Excessive involvement in pleasurable activities with high potential for painful consequence (e.g. buying sprees, gambling)

Hypomania
- Episodes lasting only days
- No marked functional impairment, psychotic features or hospitalisation

20
Q

Drug-induced psychosis vs Schizophrenia

21
Q

Psychosis prognosis

A

Up to 25% secondary depression
10-15% die by suicide

Worse prognosis
- Early onset
- Social isolation
- Poor compliance
- Lack of insight
- Prominent negative symptoms

Better prognosis
- Acute onset
- Normal pre-morbid personality
- Definite precipitating factor

22
Q

Schizophrenia DSM V criteria

A

At least 2 of:
- Delusions
- Hallucinations
- Disorganised speech
- Grossly disorganised or catatonic behaviour
- Negative symptoms incl.:
- Lack of motivation
- Poor self-care
- Blunted affect
- Reduced speech output
- Social withdrawal
- Impaired cognitive functioning common

Lasting >6mo incl. prodrome
- Rapid deterioration in social function suggest another cause

Exclusion of substance use and/or medical cause

23
Q

Antipsychotic MOA + first and second gen differences

A

D2 receptor competitive antagonist
- Except aripiprazole (partial agonist)

Second gen = higher 5-HT2 receptor blockade

24
Q

Antipsychotic adverse effects

A

Extrapyramidal: acute dystonia, akathia, parkinsonism, tardive dyskinesia
- Lower in second gen

Weight gain - esp. olanz, cloz + quetiapine

Diabetes - esp. olanz + cloz

Hyperprolactinaemia, sexual dysfunction - esp. first gen, risperidone

QTc prolongation - esp. amisulpride, halo, ziprasidone

Sedation

Orthostatic hypotension

Rabbit syndrome: rapid contraction of perioral musculature
- Most common in women, asian decent, middle and old age

25
Clozapine myocarditis - onset, symptoms, investigations and management
1:1000 at initiation of therapy Onset within 2 months (~3/52) S+S: - Chest pain, SOB, heart failure - Fever, tachy, hypotensive Ix: Trop >2x ULN CRP >100 (in 70%) - Both together, highly specific ECG - prolonged QTc, non-specific ST changes TTE Mx: Cease clozapine if CRP >100 + trop 2x ULN Supportive
26
Somatisation vs factitious vs malingering
Somatisation - Lack of insight Factitious - Intentional but no secondary gain beyond sick role Malingering - Intentional with secondary gain e.g. avoiding work, financial compensation, drug-seeking etc.
27
Frequent presenter to ED - definition and associations
>5 presentations/year (most common; many others) EtOH/substance avuse Mental illness esp. personality disorders Males Exposure to violence Unemployment Homelessness
28
Management of ED frequent presenters
Immediate - Senior staff to manage - Avoid unnecessary investigations - Manage underlying disease Long term - Notification of state drug and poisons if drug-seeking - Issue an ED alert - Management plan development - Guardianship boards/police in extreme cases - Restraining orders in cases of repeated threatening behaviours *A designated mental health team ineffective in reducing attendance rate*
29
Anorexia: indications for hospitalisation
Medical - HR <40 - BP <90/60 - Symptomatic hypoglycaemia - Temp <36.0 degC - Dehydration - K <3.0 mmol/L - Na < 130 mmol/L - Phos <0.5 mmol/L - Prolonged QTc Weight related - Weight <75% expected - Weight loss >1kg in 1 week - Unable to eat independently - Requiring NG feeding Psychological - Failure of outpatient management - Severe coexisting psychiatric disease
30
Eating disorders: treatment and prognosis (bulimia, anorexia)
Weekly CBT - 20 weeks bulimia - 40 weeks anorexia Family-based therapy in adolescents and children SSRI + CBT more effective than either alone Recovery rate by 9 years of treatment: - Bulimia 65% - Anorexia 50% Highest mortality of all psychiatric disordres - 0.5% per annum - More frequently suicide than starvation
31
Features of psychosis
- Delusions - Hallucinations - Disorganised speech - Grossly disorganised or catatonic behaviour - Negative symptoms incl.: - Lack of motivation - Poor self-care - Blunted affect - Reduced speech output - Social withdrawal
32
Long term complications of eating disorders
Osteoporosis Short stature Stress fractures Abnormalities in cognitive function - ​loss of grey matter during starvation may persist Higher miscarriage rate Lower infant birth weight Renal calculi
33
Diagnostic criteria of anorexia nervosa
1. BMI <17.5 or BW <85% expected 2. Weight loss self-induced 3. One of more of: - Body image distortion - Self-induced vomiting or purging - Excessive exercise - Associated endocrine disorders (e.g. amenorrhoea for >3 consecutive months post-menarche)
34
Features of behavioural disturbance presentation suggestive of psychiatric cause
Past history of psychiatric disorder Current presentation similar to previous psych presentations Normal vitals No acute drug intoxication / normal physical examination Auditory hallucinations Collateral history suggestive of slow onset deterioration No medical symptoms / complaints
35
Components of competence assessment
Age - No absolute rules - >18 years, considered competent - 14-17 variable - <14 usually considered not competent Cognitive capacity to understand - Medical condition - Options for treatment - What is recommended - Potential adverse outcomes - Likelihood of these Should be able to: - Accept information as reality - Retain information provided - Paraphrase information - Explain the possible consequences - Indicate the major facts in the their decision OR Understands: - Current condition - Treatment options - Possible outcomes of each option Can retain, repeat back and paraphrase information
36
Risk factors for post-natal depression
- History of depression - Prior post-partum depression - History of other mental illness – bipolar - Recent stressors – pregnancy complications, job issues, health problems - Baby has health problems or special needs - Feeding difficulties - Relationship issues/DV - Lack of supports - Unwanted pregnancy
37
Indications for admission for post-natal depression
1. Psychosis 2. Admission of thoughts of infanticide/harm 3. Thoughts of self-harm 4. Any suicidality (any other SADPERSONS type stuff) 5. Poor social supports
38
Complications of refeeding syndrome
Hypophosphataemia Hypokalaemia CCF Peripheral Oedema Rhabdomyolysis Seizures Haemolysis
39
Components of Mental State Examination
ABS MAT PCI Appearance and behaviour Speech Mood Affect Thoughts Perception Cognition Insight and judgment
40
Risk factors for high suicide risk
Mix of SADPERSONS + past history and means - High intent/ continual or specific thoughts - Definite plan - Hopelessness - Severe depression - Psychosis/ command hallucinations/ delusions about dying - Past attempts/ high lethality attempts - Impulsivity/ changeability/ lack of rapport - Intoxication/ substance abuse/ dependence - Male gender - Recent psychiatric hospitalisation - Access to means - Lack of supportive relationships/ social isolation - Conflicting information/ unable to verify information
41
Low risk criteria for "Medical Clearance" or "Completion of Medical Assessment"
- Age 16-65 years - No acute physical health problems (including trauma, ingestion or drug side-effects) - No altered level of consciousness - No evidence of physical cause for the acute presentation /normal vitals and examination - Not the first or significantly different psychiatric presentation
42
ECG: 15F BMI 15. Describe ECG findings, likely cause and potential cardiac complications
Widespread ST depression with TWI and U waves Significantly prolonged QU interval Consistent with severe hypoK Risk of VT, VF, Torsades de Pointes
43
Steps to locating absconded mental health patient without completed assessment
1. Security to search premises 2. Attempt to contact patient by his listed mobile phone. 3. Notify police that patient has absconded & request welfare check at listed address 4. Notify NOK that patient has absconded & ask them to bring him back to ED if they have contact with him. 5. Notify psychiatric unit that patient on involuntary order has absconded 6. Document attempts to locate patient in chart
44
Overarching goals for inpatient treatment of anorexia nervosa
1. Medical stabilization of medical complications eg cardiac failure 2. Prevent or manage refeeding syndrome 3. Weight restoration 4. Reversal of cognitive deficit due to starvation 5. Inpatient psychotherapy