psychopathology Flashcards
(75 cards)
how does drug therapy treat OCD?
increase or decreases levels of neurotransmitters in the brain
what is OCD thought to be caused by?
low levels of serotonin in the brain
what drugs are used to treat OCD?
SSRIs (selective serotonin reuptake inhibitors)
how do SSRIs work?
prevent reabsorption and break down of serotonin by the pre-synaptic neuron. This means that the levels of serotonin in the synapse increase and can continue to stimulate the post-synaptic neuron
what is an example of an SSRI?
Fluoxetine
What is a typical daily dose of Fluoxetine?
20mg
how long does it take for SSRIs to have an impact on symptoms?
three or four months of daily use
what is an alternative to SSRIs?
tricyclics such as Clomipramine
why are tricyclics used as a reserve?
they have more severe side effects
What is another alternative to SSRIs?
Serotonin-noradrenaline reuptake inhibitors which increase levels of serotonin as well as noradrenaline
what can be used alongside drugs to treat OCD?
CBT
how does drug treatment enable patients to engage in CBT?
reduce a patients emotional symptoms such as feeling anxious or depressed
what are the 2 biological explanations for OCD?
•genetic
•neural
how do parents give offspring OCD?
hereditary influences by genetic transmission
what did Lewis (1936) find?
observed that of his OCD patients 37% had parents with OCD and 21% had siblings with OCD
do genes cause OCD?
no it is genetic vulnerability that runs in families
what does the diathesis stress model suggest?
an environmental stress is needed to trigger OCD as well as genetic vulnerability
what is a candidate gene?
creates vulnerability for OCD
what is an example of a candidate gene?
5HT1-D beta
what does 5HT1-D beta do?
it is involved in the efficiency of transport of serotonin across synapses
what does OCD is polygenic mean?
it is not caused by one single gene but several genes are involved
what did Taylor (2013) find?
found evidence that up to 230 genes may be involved in OCD. These genes are thought to be associated with the action of dopamine as well as serotonin.
what does OCD is aetiologically heterogeneous mean?
the origin of OCD has different causes. one group of genes may cause OCD in one person, but a different group of genes may cause the disorder in another person
what does neural mean?
relating to a nerve or to the nervous system