Psychopharm Flashcards

1
Q

What is dopamine involved in (4)

A

Fine muscle movement
Decision making
Release of hormones
Integration of emotion and thoughts

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2
Q

What disorders result from too much dopamine

A

Schizophrenia
Psychosis
Mania

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3
Q

What disorder result from not enough dopamine (2)

A

Parkinson’s
Depression

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4
Q

What is Norepineprhine (NE) involved in (4)

A

Mood
Attention
Arousal
SNS stimulation

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5
Q

What disorder is too much NE

A

Mania
Anxiety
Psychosis
Heightened arousal state

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6
Q

What disorders are from too little NE (2)

A

Depression
Lowered arousal state

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7
Q

What is serotonin ( 5HT) involved in (7)

A

Sleep regulation
Hunger
Mood
Pain
Libido
Aggression
Hormonal activity

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8
Q

What disorder is too much 5-HT

A

Anxiety

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9
Q

What disorder is too little (5-HT)

A

Depression

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10
Q

What is Histamine involved in (3)

A

Alertness
Gastric secretion
Inflammation response

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11
Q

What neurotransmitters are monamines (4)

A

Dopamine
Norepinephrine
Serotonin
Histamine

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12
Q

What is Y- Aminobutyric acid (gaba) involved in (4)

A

Decreased anxiety
Decreases excitement
Decreases aggression
Anticonvulsant

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13
Q

What disorder can happen with too little gaba

A

Mania
Anxiety
Psychosis

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14
Q

What can happen with too much gaba

A

Reduction of anxiety

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15
Q

What is glutamate responsible for? (3)

A

Memory
Emotion
Cognition

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16
Q

What disorders can result from too much gaba (3)

A

Increase perception of pain
Anxiety
Restlessness

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17
Q

What disorders can result from too little glutamate (4)

A

Low energy
Difficulty concentrating
Insomnia
Psychosis

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18
Q

What are the amino acid neurotransmitters

A

GABA
Glutamate

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19
Q

What is acetylcholine responsible for (5)

A

PNS stimulant
Sexual and aggressive behavior
Memory
Learning
Mood regulation

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20
Q

What disorders come from too much acetylcholine

A

Depression

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21
Q

What disorders result from too much acetylcholine

A

Depression

22
Q

What disorders result from too little acetylcholine

A

Alzheimer’s
Parkinson’s
Huntingtons chorea

23
Q

Which neurotransmitter is a cholinergic

A

Acetylcholine

24
Q

What meds are considered antidepressants (4)

A

TCA
MAOIs
SSRIs
SNRIs

25
Q

What are some patient teachings with SSRI Take with?
Avoid?
Medication should not
Take how long
Tell physican when

A

Take with food in AM
Taking with alcohol and antihistamines
Shouldn’t be stopped abruptly
1-3 weeks to work
Suicidal thoughts increase

26
Q

What are some s/s of SSRI withdrawals

A

HA, anxiety, insomnia, irritability, achy muscles and chills, dizziness, tiredness

27
Q

What are some SSRI side effects

A

Sexual disjunction
Insomnia
Bruxism- grinding of teeth in sleep
Dry mouth
Anxiety/agitation

28
Q

What are some s/s of serotonin syndrome (SHIVERS)

A

Shivering
Hyper reflex is
Increased temperature
Vital signs instability
Encephalopathy
Restlessness
Sweating

29
Q

What are some nursing interventions for Serotonin syndrome

A

Discounting offending agent
Maintain safe environment
Monitor physical and mental status
Give serotonin receptor blockers, dantrolene or diazepam

30
Q

What are some side effects of TCA (5)

A

Sedations
Sexual dysfunction
Toxicity
Anticholinergic effects
Orthostatic hypotension

31
Q

What are some patient teaching with TCA

A

Avoid alcohol
Lethal in overdose
take in evening
4-8 weeks

32
Q

What are some side effects of MAOIs (4)

A

Sexual dysfunction
Anticholinerigcs effects
Food/drug interaction (Tyramine)
Hypertensive crisis

33
Q

What are some foods with tyramine

A

Aged cheeses/meat
Soy
Yeast
Alcohol
Avocados and bananas

34
Q

How long should the tyramine free diet last after stopping MAOIs

A

2 weeks

35
Q

What are some general side effects of antipsychotics (3)

A

Anticholinergic effects
Weight gain
Sedations

36
Q

What are some 1st generation side effects

A

Orthostatic hypotension
EPS

37
Q

What are some 2nd generation antipsychotic side effects

A

DMT2
Dyslidpidema
Aganularcyctosis

38
Q

What are some pt teaching for 1st gen antipsychotics

A

Sun exposure
Change position slowly
2-4 weeks

39
Q

What are some pt teaching for 2 gen antipsychotics

A

Monitor s/s diabetes
Observe signs of infections

40
Q

What are some EPS s/s (4)

A

Acute dystonia
Akathesia
Pseudoparkinsonism
Tardive dyskinesia

41
Q

What are some s/s of pseudoparkinsonism TRAP

A

Tremors
Rigidity
Akinesia/bradykensia
Postural gait

42
Q

What is akathisia

A

Restless
Trouble standing still

43
Q

What are some s/s of acute dystonia

A

Involuntary facial muscle spasms

44
Q

What are some s/s of tardive dyskinesia (3)

A

rolling of tongue
Chewing motion
Facial dyskinesia

45
Q

What is NMS

A

Neuroleptic malignant syndrome
Caused by using antipsychotics

46
Q

What are some s/s NMS (6)

A

Drooling
High fevers
Sweating
Decrease LOC
Muscle rigidity
Tachycardia/tachypnea

47
Q

What are some nursing interventions for NMS

A

Stop antipsychotic medication
Increase fluids
Give dantorlene, sedations, antipyretics
consider intubation if needed

48
Q

What are some patient teaching with benzodiazepines (4)

A

Avoid alcohol
Caution with driving
Withdrawal is fatal
Highly addictive

49
Q

What are some early withdrawal s/s of benzos

A

Anxiety
Sweating
Tremors
Dizziness

50
Q

What are some long term s/s of withdrawal of benzos

A

Panic
Paranoia
Delirium
HTN
Muscle twitches
Seizures

51
Q

What is the therapeutic ranges for lithium

A

0.5-1.2

52
Q

What is the toxic level for lithium

A

> 1.5