Psychopharmacy Flashcards
(22 cards)
How long do antidepressants take to start working
Take 4-6 weeks to start working.
How should monitoring be conducted for antidepressants?
Do a baseline monitor, then weekly for 4 weeks, then bi-weekly.
What is a concern for people under 30 when starting antidepressants?
Increased risk of suicide when first starting
How long should antidepressants be taken if they are working?
At least 6 months.
What is the recommended tapering period after improvement?
Wean over 4 weeks to prevent serotonin discontinuation syndrome.
What does SSRI stand for?
Selective Serotonin Reuptake Inhibitor.
What are some examples of SSRIs?
Sertraline, Fluoxetine, Paroxetine, Citalopram.
What is a significant side effect of Citalopram?
QTc prolongation.
What are common gastrointestinal side effects of SSRIs?
Nausea, vomiting, pain
What is a risk when taking SSRIs with NSAIDs?
Increased gastrointestinal bleeding risk.
Take PPI alongside to protect
What are some potential interactions with SSRIs?
Decreased effiacy of triptans
NSAIDs - GI bleed
What are some sexual side effects of SSRIs?
Impotence and libido changes.
What is serotonin syndrome?
Can be a side effects of SSRI
A potentially life-threatening condition caused by excessive serotonin.
What is hyponatremia?
Can be a side effect of SSRI
Low sodium levels in the blood.
What are the pregnancy considerations for Paroxetine?
1st trimester → increased CHD risk and cleft palate
3rd trimester → PPHN risk.
What is Sertraline effective for
General anxiety disorder
Depression
Pro and con of paroxetine
Increased risk of discontinuous syndrome
Good for breast feeding
Pros of fluoxetine
Often used in CAMHS
Good for breastfeeding
What does SNRI stand for?
Serotonin-Norepinephrine Reuptake Inhibitor
Name two examples of SNRIs.
Venlafaxine and Duloxetine
What condition are SNRIs good for?
Stress incontinence
What are some side effects of SNRIs?
Nausea, vomiting, dry mouth, rhabdomyolysis, SIADH
