Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

MCQs > Psychscene Miscellaneous > Flashcards

Psychscene Miscellaneous Flashcards

(71 cards)

Start Studying
1
Q

Structural classes of antipsychotics?

A
  1. Phenothiazines 2. Butyrophenones 3. Thioxanthines 4. Substituted Benzamides Dibenzazepine 5. Dibenzodiazepine 6. Thienobenzadiazepine 7. Dibenzothiazepine 8. Benzisoxazole
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Phenothiazines?

A

ChlorPromazine FluPhenazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Butyrophenones?

A

Haloperidol - D2 blockade

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

ThioXanthines?

A

FlupenthiXol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Dibenzodiazepine?

A

Clozapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Thienobenzodiazepine?

A

Olanzapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Dibenzothiazepine?

A

Quetiapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Benzisoxazole

A

Risperidone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Piperazine

A

Trifluoperazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Piperidine

A

Thioridazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Benzamide?

A

Sulpride

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Mechanism of Haloperidol?

A

D2 blockade

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Mechanism of Sulpride?

A

D3 presynaptic antagonist at low doses, D2 post synaptic antagonist at high doses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Why is Sulpride different from the others?

A

It does not follow the pharmacokinetic principles of the other antipsychotics so it is… -water soluble/poorly fat soluble -poorly absorbed -doesn’t cross the BBB as well as the others

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

D2D - What do SSRIs do to Cytochrome P450?

A

Inhibit it. So it can raise plasma levels of Haloperidol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

D2D - What does smoking do to enzymes?

A

Enzyme induction. Therefore it lowers plasma concentrations of antipsychotics.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Safe antipsychotics in pregnancy?

A

Haloperidol (no good reason) Atypicals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Mechanism of Risperidone?

A

5HT2:D2 antagonist A1 blockade leads to FIRST DOSE HYPOTENSION.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Mechanism of Olanzapine?

A

5HT2:D2 antagonist H1 blockade causes SEDATION

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Mechanism of Quetiapine?

A

5HT2:D2 antagonist H1 blockade causes SEDATION

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Mechanism of Clozapine?

A

D4 & D1 antagonist. Highest affinity for 5HT2 than other antipsychotics. D2 receptor occupancy of 50-60% at therapeutic levels.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Mechanism of Aripiprazole?

A

D2 Partial agonist, 5HT1 partial agonist 5HT2a antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What causes EPSEs?

A

High (>80%) central D2 receptor occupancy.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

How can you treat EPSEs?

A

Anticholinergics or dose reduction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
What is dystonia?
Muscle spasms - occur when starting antipsychotics. Can be treated with IV/IM anticholinergics Can be prevented by co-administering anticholinergics for 4-7 days of initiation.
26
What is akathisia?
Motor restlessness/inability to sit still.
27
What causes akathisia?
Decreased D2 activity in the basal ganglia. Rating scale - BAS - Barnes Akathisia Scale.
28
How do you treat akathisia?
B blockers Benzos
29
MacArthur Violence Risk Assessment Study
ETOH and drug use accounted for increased incidence of violence, for 20 weeks post discharge. If they didn't use drugs or ETOH, acute inpatients were NO MORE LIKELY THAN CONTROLS TO COMMIT VIOLENCE.
30
VIOLENCE RATING SCALES
V's and S's VRAG HCR-20-historical clinical risk VRS Static 99-sexual recidivism SORAG-sex offender risk appraisal
31
Mens Rea Actus Rea
To be convicted prosecution needs to prove : guilty mind, guilty action
32
Sane Automatism Vs Insane Automatism
Sane Automatism - person reacting to external factor (consussion, spasm, killing someone while SNEEZING) Insane Automatism - person reacting to internal factor (disease of the mind)
33
Provocation
- when a person commits a crime due to a preceding act - PARTIAL DEFENCE - only reduces murder charges to manslaughter - crime caused by provocation, committed in the heat of passion under an irresistable urge, without being determined by reason
34
Malice Afterthought Vs Furor Brevis
Malice Afterthought - under the sway of reason Furor Brevis - deaf to the voice of reason even though the act was intentional
35
Catatonia
Karl Kahlbaum
36
Vaillants Defense Mechanisms
I - PATHOLOGICAL II - IMMATURE III - NEUROTIC IV - MATURE
37
38
Sublimation
MATURE - transform unhelpful emotions into constructive behaviour - play sport to deal with aggression
39
Displacement
- NEUROTIC DEFENCE - shift impulse onto something or someone else (less threatening target) - redirecting emotion from the real object to a different one
40
Doing and Undoing
- NEUROTIC - after doing something regretable, trying to undo it
41
Externilization
- projecting your own internal characteristics onto others - perceiving others as argumentative when YOU are the argumentative one
42
Isolation
-seperating ones thoughts from their feelings
43
Projection
- IMMATURE - primitive form of paranoia - attributing your own unwanted thoughts or desires onto another - hypervigilant, injustice collecting
44
Raven's Progressive Matrices
Non Verbal Intelligence
45
Ray Osterrieth Test
VISUAL MEMORY WORKING MEMORY EXECUTIVE FAMILY
46
WISCONSIN CARD SORTING TEST
EXECUTIVE FUNCTIONING abstraction, set shifting, attention
47
EEG in CJD
PSWC - periodic sharp wave complexes diffuse slowing and... FIRDA - fronal rhythmic delta activity
48
EEG in HSE
UNILATERAL/BILATERAL PERIODIC SHARP WAVES FOCAL/LATERALIZED SEIZURE + ENCEPHALITIS
49
EEG IN HUNTINGTONS
Slow, gradual EEG slowing
50
EEG in Metabolic/Hepatic Encephalopathy
TRIPHASIC WAVES
51
EEG IN MYOCLONIC EPILEPSY
3-6 Hz, POLYSPIKE AND WAVE
52
CYP enzymes?
CYP 1A2 CYP 2D6 CYP 3A4 CYP 2C9 CYP 2C19
53
54
Sodium Valproate interactions
- highly protein bound (poor volume of distribution). - displaces other drugs that are protein bound (and so, there will be more free drug in the blood stream) - other protein bound drugs include : CARBAMAZEPINE WARFARIN PHENYTOIN TOPIRAMATE Therefore if you give valproate with any of these, their drug levels will go up.
55
Intraversion/Extroversion
JUNG introversion - orientation in life through subjective psychosis content extraversion - concentration of interest on external object
56
Models of Personality
Big 5 Eysenck's 3 Cattell's 16 PF MMPI Myers Briggs Jungian Analytical Psychology
57
Analytical Psychology (Jungian)
Anima and Animus feminine side of a man, masculine side of the woman (unconcious) Archetypes (the mother, the child, the trickster) Collective Unconcious "To have a complex"
58
Myer Briggs Type Indicator
self report INFJ/ENFP based on jungian analysis
59
16PF
CATTELL clinical instrument used by professionals
60
61
Working Memory
- hold info temporarily - used for reasoning and decision making
62
Sensory Memory
-recall great detail about a complex stimulus immediately following the presentation but for like a second. no manipulation of memory -immediately transferred to working memory
63
Working Memory BADDELEY AND HITCH
Working memory has... - phonological loop - way of remembering auditory information (like phone numbers) and consists of a short term pholological loop (rapid decay) and an articulatory loop that can revive the memory trace - visuospatial scratchpad - information about position and properties of objects are stored. - central executive to disperse attention between them and also links working memory to the long term memory
64
Long term memory
final stage semi permanent infinite capacity divided into IMPLICIT and EXPLICIT
65
Explicit Memory
- semantic or episodic - semantic are abstract and fact based - episodic are event based
66
Implicit Memory
-procedural memory for motor tasks
67
BIOPSYCHOSOCIAL MODEL
ENGEL
68
D
69
DIATHESIS-STRESS MODEL OF PSYCHOPATHOLOGY
AARON BECK
70
GENETIC DETERMINISM
AUGUST WEISMANN, 1890
71
PATIENT CENTERED CARE
BROWN AND STEWART Remember "Stuart Brown\* is very patient centered

MCQs (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions