Public Health Flashcards
(248 cards)
What is Public Health?
The science and art of preventing disease, prolonging life and promoting health through organised efforts of society
Define Epidemiology
The study of frequency, distribution and determinants of disease and health related states in populations in order to prevent and control disease
Define incidence
Number of new cases of a disease in a population in a given time frame (new cases per 1000 per year)
- The rate at which new disease occur in a population in a certain time period
Define Prevalence
Existing cases in a population at a point in time (total number of people with a condition per 100,000 per year)
What is Person time?
Measure of time at risk = time from entry to a study to
- Disease onset
- Loss to follow up
- End of study
Used as the denominator to calculate incidence rate
Define incidence rate
Number of person who have become cases in a given period of time / total person time at risk during that period
What is meant by absolute risk?
Actual numbers involved and has units
e.g. 50 deaths per 1000 people
What is meant by relative risk?
The ratio of risk in one category relative to another
E.g. risk in exposed compared to the risk in unexposed
Tells us the strength of association between risk factor and disease
How is relative risk calculated?
Incidence in exposed ÷ incidence in unexposed
Define attributable risk
Rate of disease in the exposure that may be attributed to the exposure
- Tells us about the size of effect in absolute terms
How is attributable risk calculated?
Incidence in exposed - incidence in unexposed
If the incidence of disease A in smokers is 1/1000 person years and 0.05/1000 person years in non smokers, what is the attributable risk?
1-0.05 = 0.95/1000 person years
If the incidence of disease A in smokers is 1/1000 person years and 0.05/1000 person years in non smokers, what is the relative risk?
1/0.05 = 20 (no units)
If the incidence of disease B is 8/1000 person years and incidence of disease B in non-smokers is 4/1000 person years what is the attributable risk?
8 - 4 = 4/1000 person years
If the incidence of disease B is 8/1000 person years and incidence of disease B in non-smokers is 4/1000 person years what is the relative risk?
8/4 = 2 (No units)
What is relative risk reduction?
Reduction in the rate of the outcome in the intervention group relative to the control group
How is relative risk reduction calculate?
1 - relative risk
OR
(incidence in non exposed - incidence in exposed) ÷ incidence in non exposed
What is absolute risk reduction?
Absolute difference in the rate of events between the 2 groups
Gives an indication fo the baseline risk and the intervention effect
How is absolute risk reduction calculate?
Incidence in non exposed - incidence in exposed
Define Number Need to Treat (NNT)
Number of patients needed to treat to prevent one bad outcome
How is NNT calculated?
1 / Absolute risk reduction
OR
1 / (incidence in non exposed - incidence in exposed)
What is meant by odds?
Odds of an event is the ratio of the probability of an occurrence compared to the probability of non-occurrence
How Is Odds calculated?
Probability / (1 - Probability)
What are the 5 factors that could be responsible if a study finds an association between exposure and an outcome?
- Bias
- Chance
- Confounding factors
- Reverse causality
- A true causal association