public health Flashcards
Epigenetics
Expression of a genome depends on the environment, biology and biography
genetic disposition- key
everyones experiences are different
Allostasis
Stability through change, physiological system rapidly reacting to environmental stresses e.g. CVS (to HTN) and endocrine (obesity)
Allostatic load
Overtaxation of our physiological system that leads to impairment of health (stress)
Salutogenesis
Favourable physiological change that promotes healing and health
Emotional intelligence
Having control of your own and others emotions
- identify and manage emotions
Primary Care
- prevent illness
- promote health
- work along side patients
- managing clinical uncertainty
- getting the best outcome with available resources
What it takes to be a GP
- generalist- broad knowledge
- coordinator
- excellent com skills
- good listener and has good judgement
ABx- which given for OM, sinusitis, tonsillitis, LRTI and UTI
OM, sinusitis, LRTI- amoxicillin for 5 days
tonsillitis: penicillin V for 10 days
UTI- trimethoprim or nitrofurantoin for 3 days
When to prescribe AB in
1. OM
2. Tonsillitis
What are the complications of the above if not prescribed
OM- 1. Bilateral OM under 2 yrs old OR 2. OM with otorrhea (fluid). comp= mastoditis
Tonsillitis: 3 or more in CENTOR CRITERIA or FPAIN
comp= peritonsillar abscess
ABx criteria
systemically unwell or high risk group (prem, immunocomp)
if above 65 then 2 of the following or above 80 one
1. admitted to hospital in the last 12 months
2. has diabetes
3. congested heart failure
4. on glucocorticosteriods
complications: pneumonia, cellulititis etc
Why Abx shouldn’t be over-prescribed
- ABX resistance
- unnecessary side effects
- medicalising self limiting conditions
Define public health
preventing disease
promoting health
prolonging life
through the efforts of society
Name the 3 domains of PH and give examples of each
- Health improvement- employment, housing, inequalities, LS etc
- Health protection- infectious disease, radiation
- Improving services- audits, clinical governance, equity
Determinants of Health
4 things- genes, environment, LS and healthcare
Key concerns for PH
inequality, prevention and wider determinants of health
Health intervention
can be delivered on an individual/community and popn level. Can be health/non-health related–> for PH
Define health needs assessment, need, demand and supply
Health needs assessment is a systematic method for reviewing health issues faced to improve health and reduce inequality
need- ability to benefit form an intervention
demand- what is asked for
suuply- what is provided
Define health need and health care need
health need- need for health e.g. measuring mortality and morbidity
health care need- need for health care, and ability to benefit from it
define: felt need expressed need normative need comparative need
felt need: is like demand, its what the Indi perceives of variation of normal health
expressed need: indi seeks help to overcome variation
normative need: professional defines intervention appropriate for expressed need
comparative: compares severity, cost and range of intervention
how has a doctor will you improve health
treating each ptx as an individual
providing and influencing services available
Maxwell’s dimensions on quality of health care
3E’s and A’s- effectiveness, equity and efficiency
accessibility, acceptability, and appropriateness
Define primary, secondary and tertiary prevention
Primary: preventing disease before it has happened e.g. LS changes and education
Secondary: catching it in the pre-clinical or early phases e.g. screening
Tertiary: managing the disease and preventing progression e.g. chemo, rehabilitation, meds
Define prevention paradox
a preventive measure that brings benefit to the population but minimal effect to the individual e.g. lowering alcohol consumption rates per week
What is screening
Is a secondary preventing measure aimed to identify well patient who may have the condition (or precursors) from those who don’t . NOT DIAGNOSITC
Types of screening (name 3)
- population based
- opportunistic based
- pre-employment and occupation based
- for communicable diseases
Wilson and Junger Criteria
- Condition: natural history, has a preclinical phase, important
- Test: suitable (cost, sensitivity, specific) and acceptable
- Treatment: effective and applied policy who to treat
- Organisation- cost effective, facilities and ongoing process
What does true positive and true negative mean
True positive: test said yes and they have disease
True negative: test said no and they dont have the disease
What does false negative and false positive mean
False negative: test said no have it but they have disease
False positive: test said yes but they don’t have disease
Disadvantages of screening:
- false positive can cause unnecessary distress
- well ptx are exposed to harmful tests
- over medicalising, some precursors that may not have developed may be treated
What is sensitivity
proportion of people with the disease and correctly identified from test
TP/TP and FN
What is specificity
proportion of people without the disease and correctly excluded from test
TN/ TN + FP
Positive predicted value
number of people from test who had a positive result who actually have the disease
TP/TP + FP
Negative predicted value
number of people who were told they were negative and actually dont have the disease
TN/TN +FN
what is predicted value dependent on
Prevalence
Define lead time bias
when a screening identifies a condition earlier it increases survival time, even if screening has no effect on outcome
Define length time bias
Differences in the length of time taken for a condition to progress–> affect efficacy of screening method
Examples of descriptive study designs and what they do
- Case reports- looks at individual reports
2. Ecological- use routinely collected date to look for trends- prevalence and association. NOT CAUSATIVE
Examples of descriptive and analytic
Cross-sectional study: compares two groups at one specific time. Also generate hypothesis and are also prone to bias
Examples of analytic study designs
Case-control: RETROSPECTIVE, interviewing patient with condition and identifying the association
Cohort: longitudinal study that follows risk groups to see if they get the condition
Experimental studies
Randomised control trial: placebo vs med etc
ad- less bias, can infer causality
dis- expensive, time consuming and unethical to withdraw treatment
Define dependent and independent variable
Dependent: can’t not be altered
independent is the variable that changes in experiment
Define incidence and prevalence
incidence: the number new cases in a set time e.g. 5 people were diagnosed with cancer last year
prevalence: the number of existing cases e.g. 15 cases of cancer so far
What is incidence rate and absolute risk
incidence divided by the total number of people at risk during that period e.g. 100 farms followed for a year, and 10 got the disease IR is 0.1 or 10%.
Absolute risk is with units e.g. 1 in 10 deaths per year
Attributable risk and relative risk
ARR: RATE of disease in exposed that attributed to the exposure: Incidence in exposed minus incidence in unexposed
RR: RATIO of risk of disease in exposed vs unexposed. Incidence in exposed divided by incidence in unexposed
1= no D, less than 1= intervention reduced risk and >1= intervention increased risk of outcome
what is relative risk reduction
reduction in rate of outcome in the intervention group vs control group
what is absolute risk reduction
absolute difference in the rates of events given baseline and intervention effect
Number needed to treat
NNT: number of ptx needed to treat to prevent 1 bad outcome. ARR- attributable risk reduction
1/ARR (if decimal) or 100/ARR (if %)
What is epidemiology:
A study of frequency, distribution and determinants of diseases and health related to population to prevent and control disease
* time, place and person (age, gender, ethnicity etc)
Define bias and give three types
Bias is a systemic deviation in the true estimation between exposure and outcome
- selection bias- who the participators are
- information- recall/observer
- publication
What is a confounding variable
Variable influencing both IV and DV
What is reverse causality
What cause –> effect but its the other way around
Bradford Hill criteria
For Causality
SSCC- specificity, strength of association, coherence and consistency
Define addiction
Dependence syndrome; craving, lack of control, tolerance, withdrawal state, self neglect and knowing the damage and continuing. Three or more in 12 months Dx.
Effect of drugs
Physical: acute (needle stick injury, OD, pregnancy problems) chronic (psychosis, MH, infections, poverty)
Psychological: guilt, fear and craving
Social: criminality, imprisonment, debt etc
Heroin- what it is, effects and how long it lasts
Acts on opiod receptors, used 8hrly
Powder
effect: euphoria, relaxation, drowsiness and mitosis