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GASTROINTESTINAL DISORDERS > PUD > Flashcards

PUD Flashcards

1
Q

A break in the mucous lining of the GI tract where it comes in contact with gastric juice

A

Peptic Ulcer Disease

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2
Q

Age incidence of PUD

A

30-55

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3
Q

Gender Incidence

A

more common in men

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4
Q
A
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5
Q

Predisposing Factors (HSA3Cs2GsFITTZ)

A
  1. H. pylori
  2. Stress
  3. Alcohol
  4. Cigarette Smoking
  5. Caffeine
  6. Certain Drugs (NSAIDs, aspirin, steroids (ulcerogenic)
  7. Gastritis
  8. Genetics
  9. Fatty, spicy, highly acidic foods
  10. Irregular, hurried meals
  11. Type A personality
  12. Type O blood
  13. Zollinger-Ellison syndrome
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6
Q

Other Name foe GU and DU

A

GU: Poor man or laborers ulcer
DU: executive ulcer

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7
Q

GU vs DU incidence

A

GU: 20%
DU: 80%

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8
Q

Age incidence of GU and DU

A

GU: >50
DU: 25-50

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9
Q

GU and DU affects those who are?

A

GU: malnourished
DU: well- nourished

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10
Q

Pathophysiology of GU and DU

A

GU: normal HCl secretion
DU: increased HCl secretion

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11
Q

Where does pain radiate in GU and DU?

A

GU: left side of abdomen
DU: right side of abdomen

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12
Q

When is pain experienced GU vs DU?

A

GU: 30 mins - 1hr after eating
DU: 3-4 hrs after eating (bet 12mn - 3am)

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13
Q

Food intake (GU vs DU)

A

GU: not relieved by food intake
DU: relieved by food intake

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14
Q

s/sx GU vs DU

A

GU: nausea, vomiting, hematemesis
DU: melena

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15
Q

Complications GU vs DU

A

GU: Hemorrhage, perforation, peritonitis
DU: obstruction, hemorrhage, perforation, peritonitis

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16
Q

Neutralizes HCL, stimulate gastric mucosal defenses, aiding in ulcer healing, Provide rapid relief of ulcer symptoms

17
Q

Antacids causes _______
Best taken ______ after meals

A

Constipation
1-2 hours

18
Q

Inhibit histamine binding to the receptors on the gastric parietal cells to reduce gastric acid secretion

A

H2 Receptor blockers

19
Q

H2 receptor blockers is best taken in the ____ and ___ (twice a day)

A

morning and bedtime

20
Q

SE of H2 receptor blockers (ADDCW)

A

Abdominal Cramps
Diarrhea
Dizziness
Confusion
Weakness

21
Q

SE of Cimetidine (CAPDADGID)

A

Confusion
Agitation
Psychosis
Depression
Anxiety
Disorientation
Gynecomastia
Impotence
Decrease Libido

22
Q

A cytoprotective drug that coats the ulcers, binds to proteins in the ulcer base, forming a protective barrier against acid, bile and pepsin. It also stimulates the secretion of mucus, HCO3 and prostaglandin

A

Sucralfate

23
Q

When should sucralfate be administered?

A

on empty stomach (30-60 minutes before meals)

24
Q

Common SE of sucralfate

A

constipation

25
Sucralfate should be administered ___ apart from antacid
1 hour
26
Replaces gastric prostaglandin, promote ulcer healing by stimulating mucus and bicarbonate secretions and by inhibiting acid secretion
Prostaglandin Analogue
27
Cytotec should be administered with?
meals
28
Common SE of prostaglandin analogue
Diarrhea Abd pain
29
Suppresses gastric acid secretion, bind the acid secreting enzyme (H+K+ ATPase)
Proton Pump Inhibitors
30
Common SE of PPI
Headache Abd pain Nausea Diarrhea
31
H. Pylori Drug Treatment
o Amoxil (amoxicillin) o Biaxin (clarithromycin) o Flagyl (metronidazole) o Achromycin (tetracycline)
32
Nsg consi for H.pylori tx
a. Advise client to avoid alcohol when on Flagyl therapy (to prevent disulfiram-like manifestations) b. Tetracycline is teratogenic (contraindicated in pregnancy) c. Advise the client to avoid alcohol (to prevent disulfiram-like manifestations
33
Disulfiram-like manifestations (HHNTPCDRC)
Headache Hypotension Nausea and vomiting Tachycardia Palpitations Chest pain Dyspnea Respiraory and circulatory collapse Convulsions
34
Nsg interventions
a. Balanced meals at regular intervals (DAT – avoid fatty, spicy and other irritants) b. Bland or restrictive diets are no longer necessary Bland diet only during exacerbation) c. Small, frequent feeding during exacerbations d. Mild alcohol intake is not harmful (as long as not excessive) e. Smoking discouraged (contains nicotine) f. Regular pattern of exercise (can release stress – endorphins) g. Stress reduction at home h. Develop recreation and hobbies; coping through stress i. Avoid the following (irritants):  Fatty foods, coffee, chocolate, cola drinks, spices, Red/black pepper(irritants)  Bed time snacks (to prevent night-time reflux/regurgitation)  Binge eating (to prevent ↑gastric motility)  Large quantities of milk (milk is alkaline: increases HCL secretion to neutralize it, causing rebound acidity)  Recommended milk intake per day: 400mLs of milk or 2 glasses/day

GASTROINTESTINAL DISORDERS (8 decks)

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