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Pulmonology > Pulm Pharm > Flashcards

Pulm Pharm Flashcards

1
Q

List some albuterol rescue inhalers

A

ProAir, Proventil, Ventolin

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2
Q

List an ICS/SABA inhaler

A

Airsupra (Budesonide/Albuterol)

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3
Q

What are ICS/SABA inhalers used for

A

asthma relief

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4
Q

List some SABA nebulizer solutions

A

albuterol sulfate & levalbuterol HCl

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5
Q

List 4 ICS/LABA inhalers

A

Symbicort (Budesonide/Formoterol)

Dulera (Mometasone/Formoterol)

Advair Diskus/HFA (Fluticasone/Salmeterol)

Breo Ellipta (Fluticasone/Vilanterol)

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6
Q

List 2 LABA inhalers for COPD

A

Striverdi Respimat (Olodaterol)

Servent Diskus (Salmeterol)

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7
Q

List 2 LABA nebulizer solutions for COPD

A

Brovana (Aformoterol) & Perforomist (Formoterol)

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8
Q

List one SAMA inhaler

A

Atrovent HFA (Ipratropium)

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9
Q

List a SAMA/SABA inhaler

A

Combivent Respimat (Ipratroprium/Albuterol)

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10
Q

List a SAMA/SABA nebulizer solutions

A

Ipratropium Bromide (DuoNeb)

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11
Q

List 2 LAMA inhalers

A

Spiriva Handihaler/Respimat (Tiotropium)

Incruse Ellipta (Umeclidinium)

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12
Q

List some ICS inhalers

A
  • Beclomethasone HFA (Qvar RediHaler)
  • Budesonide DPI (Pulmicort Flexhaler)
  • Ciclesonide HFA (Alvesco)
  • Fluticasone Proprionate HFA (Flovent HFA)
  • Fluticasone Propionate DPI (Armonair Digihaler)
  • Fluticasone Furoate DPI (Arnuity Ellipta)
  • Mometasone DPI (Asmanex Twisthaler)
  • Mometasone HFA (Asmanex HFA)
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13
Q

List 3 LABA/LAMA inhalers

A
  • Stiolto Respimat (Olodaterol/Tiotropium)
  • Anoro Ellipta (vilanterol/umeclidinium)
  • Bevespi (Formoterol fumarate/glycopyrolate)
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14
Q

List 2 ICS/LABA/LAMA inhalers

A
  • Trelegy Ellipta (Fluticasone/Umeclidinium/Vilanterol)
  • Breztri Aerosphere (Budesonide/Glycopyrolate/Formoterol)
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15
Q

List one leukotriene inhibitor

A

Montelukast (Singulair) PO

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16
Q

List the core TB drugs

A

RIPE-s

R: Rifampin
I: Isonazid
P: Pyrazinamide
E: Ethambutol
S: Streptomycin (IV)

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17
Q

List some AEs of SABAs and LABAs

A

tachycardia, muscle tremor, hypokalemia, restlessness, metabolic effects

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18
Q

What are SABAs used for

A
  • acute asthma/COPD exacerbations
  • PRN usage
  • preventative usage

albuterol, levalbuterol, fenoterol

19
Q

What are LABAs used for

A
  • scheduled maintenance for asthma/COPD
  • best used in combo with ICS or LAMA

formoterol, salmeterol, oladaterol

20
Q

What are SAMAs used for

A
  • combo with albuterol as a rescue inhaler or for exacerbations
  • can use 3-4x daily for COPD
  • PRN monotherapy NOT recommended d/t longer onset

ipratropium bromide

21
Q

What are LAMAs used for

A
  • drug of choice for COPD
  • can increase FEV and decrease moderate exacerbations
  • can also be used for asthma

tiotropium, umeclidinium

22
Q

What are some AEs of SAMAs & LAMAs

A
  • small rebound increase in airway responsiveness, dry mouth, bitter taste, urinary retention in older pts
23
Q

What are ICSs used for

A
  • first line for persistent asthma in combo with SABA or LABA
  • add-on for COPD

Fluticasone propionate/furoate, beclometasone, mometasone, budesonide

24
Q

What are some AEs of ICSs

A

pharyngitis, thrush, hoarseness, increased IOP, pituitary axis suppression, growth deceleration

25
Q

What are ICS/SABAs used for

A

asthma reliever PRN

(budesonide/albuterol)

26
Q

What are ICS/LABAs used for

A

rescue or maintenance for COPD & asthma

(symbicort, dulera, breo ellipta)

27
Q

What are ICS/LABA/LAMA used for

A
  • cut back on meds for COPD patients
  • also approved for asthma

(trelegy ellipta, breztiri aerosphere)

28
Q

What are leukotriene inhibitors used for

A
  • daily asthma treatment
  • best for pts with allergies

(montelukast)

29
Q

What is the BBW for montelukast

A

neuropsychiatric effects

30
Q

What is Dupixent used for

A

moderate to severe eosinophilic asthma and in patients 6+

31
Q

What is Xolair used for

A

moderate to severe persistent asthma

32
Q

What are some AEs of dupixent and xolair

A

Dupixent: injection site rxn, transient eosinophilia, psoriasis risk

Xolair: hypersensitivity, anaphylaxis, urticaria, injection site rxn, possible CVD risk

33
Q

List the monotherapy treatment of choice for CAP with no risk factors or allergies

A

Levofloxacin (FQ)

OR

OMadacycline (tetra)

OR

Lefamulin (pleuromutalin)

34
Q

List the combo regimen for CAP (pneumococcal and atypical coverage)

A

Anti-pneumococcal
- ampicillin sulbactam (PCN)
- amoxicillin (PCN)
- ceftriaxone (3rd G ceph)
- cefotaxime (3rd G ceph)
- ertapenem (carbapenem)

Atypical
- azithromycin (macrolide)
- doxycycline (tetracycline)

35
Q

List the monotherapy CAP regimen with MRSA coverage

A

CAP mono: Levofloxacin or moxifloxacin (FQs)

MRSA: Vancomycin (lipo/glycopeptide) or Linezolid (oxazolidinone)

36
Q

List the combo therapy for CAP with MRSA coverage

A

Combo:
- Ampicillin-sulbactam (PCN) OR ceftriaxone (3 ceph) OR cefotaxime (3 ceph) OR Ertapenem (carb)
- azithromycin (macro) OR doxycycline (tetra)

MRSA
- vancomycin (lipo/glyco) OR linezolid (oxazolid)

37
Q

List the therapy for CAP with pseudomonal coverage

A

antipneumococcal, antipseudomonal beta-lactam
- pip-tazo (PCN) OR cefepime (4 ceph) OR ceftazidime (3 ceph) OR meropenem (carb)

antipseudomonal
- ciprofloxacin OR levofloxacin (FQs)

38
Q

List the treatment for CAP with MRSA and pseudomonal coverage

A

antipneumococcal, antipseudomonal beta-lactam
- pip-tazo (PCN) OR cefepime (4 ceph) OR ceftazidime (3 ceph) OR meropenem (carb)

antipseudomonal
- ciprofloxacin OR levofloxacin (FQs)

MRSA
- vancomycin (lipo/glyco) OR linezolid (oxazolid)

39
Q

What should you give for CAP with a beta-lactam allergy and NO other risk factors

A

levofloxacin (FQ) (no aztreonam)

40
Q

What should you give for CAP with a beta-lactam allergy AND MRSA risk

A

vancomycin OR Linezolid

41
Q

What should you give for CAP with a beta-lactam allergy AND pseudomonas risk

A

One aminoglycoside (Tobramycin, gentamicin, amikacin)

AND

aztreonam (monobactam)

42
Q

What should be given for CAP with a beta-lactam allergy AND risk of both pseudomonas and MRSA

A

CAP: aztreonam & levofloxacin

AND

MRSA: Vancomycin OR linezolid

AND

Pseudomonas: Tobramycin OR gentamicin OR amikacin

43
Q

What is standard coverage for hospital acquired pneumonia

A

Standard coverage: Pip-tazo (PCN) and/or cefepime (4th ceph)

Gram-RFs: imipenem or meropenem

Carbapenem resistance hx: ceftazidime-avibactam OR ceftolozane-tazobactam OR iminpenem-cilistatin-relebactam OR meropenem-vaborbactam

Pulmonology (19 decks)

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