Pulmo, Harrison Flashcards

(36 cards)

1
Q

Condition in which venous thrombi dislodge from their site of formation and emboli to pulmonary arterial circulation

A

PE

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2
Q

PE in the setting of normal right heart function and normal systemic arterial pressure

A

Small to moderate PE

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3
Q

PE in the setting of RV hypokinesis but normal systemic arterial pressure

A

Moderate to large PE

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4
Q

PE in the setting of arterial hypotension and anatomically widespread TE

A

Massive PE

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5
Q

PE: Gender predominance

A

F

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6
Q

PE: Acquired risk factor that has a greater risk of fatal PE

A

Cancer

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7
Q

PE: Non-DVT specific risk factor that has a greater risk of fatal PE

A

Cerebrovascular disease

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8
Q

50% of DVT is due to (2)

A

1) Pelvic vein thrombosis

2) Proximal leg DVT

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9
Q

Vein thrombi that poses a lower risk of PE

A

Isolated calf vein thrombi

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10
Q

PE: First step in outpatient or ER setting with non-high clinical likelihood

A

D-dimer

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11
Q

PE: Elevated D-dimer, next step is

A

Imaging

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12
Q

PE: First step for inpatients or with high likelihood

A

1) Chest CT with contrast

2) Lung scan if with renal insufficiency or renal contrast allergy

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13
Q

COPD: Major risk factor

A

Cigarette smoking

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14
Q

COPD, normal vs slightly reduced, vs markedly reduced levels of α1 antitrypsin: M allele

A

Normal

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15
Q

COPD, normal vs slightly reduced, vs markedly reduced levels of α1 antitrypsin: S allele

A

Slightly reduced

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16
Q

COPD, normal vs slightly reduced, vs markedly reduced levels of α1 antitrypsin: Z allele

A

Markedly reduced

17
Q

COPD, normal vs slightly reduced, vs markedly reduced levels of α1 antitrypsin: Null allele

18
Q

COPD: Most common cause of exacerbation

A

Viral infections

19
Q

3 most common symptoms of COPD

A

1) Cough
2) Sputum production
3) Exertional dyspnea, frequently of long duration

20
Q

COPD: Pursed lip breathing

21
Q

Tripod position is in order to

A

Facilitate actions of SCM, scalene, and intercostal muscles

22
Q

Sign associated with paradoxical breathing

A

Hoover sign (inward movement of rib cage)

23
Q

Signs of cor pulmonale (6)

A

1) Peripheral edema
2) Ascites
3) Hepatic congestion
4) Elevated JVP
5) RV heave
6) 3rd heart sound

24
Q

T/F Chronic bronchitis without chronic airflow obstruction is not COPD

25
T/F Asthma patients can also develop chronic (not fully reversible) airflow obstruction
T
26
T/F Clubbing of fingers is not a sign of COPD
T
27
In patients with COPD, newly developed clubbing is most likely explained by
Lung CA
28
Hospitalization in COPD is recommended for (4)
1) Respiratory acidosis and hypercarbia 2) Significant hypoxemia 3) Severe underlying disease 4) Living situation not conducive to careful observation and delivery of prescribed treatment
29
2 interventions demonstrated to influence the natural history of COPD
1) Smoking cessation | 2) O2 therapy
30
The only therapy demonstrated to decrease mortality in COPD
Supplemental O2
31
COPD: Arterial pH allows classification of ventilatory failure, which is defined as
pCO2 >45mmHg
32
Principal determinant of morbidity in COPD
Degree of airway obstruction
33
COPD: Patients who continue to smoke cigarettes experience an annual decline in FEV1 of
80-100mL
34
COPD: Patients who quit smoking experience an annual decrease inFEC1 of
30mL
35
COPD: Median survival for severe disease
4 years
36
COPD: Severe disease is defined as
FEV1 less than 1L