Pulmonary Flashcards

(40 cards)

1
Q

Tx for PE in pt with GFR <30

A

Unfractionated heparin - more convenient to monitor therapeutic level with PTT
- Avoid LMWH (enoxaparin), fondaparinux, rivaroxaban

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2
Q

Pt with sudden onset chest pain, dyspnea, and hemoptysis with wedge-shaped plearual base opacification. Patient has HIV and chronic smoker

A

Pulmonary infarction from pulmonary embolism

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3
Q

38 year old with progressive SOB and cough. Smoked cigarettes for 5 years. CXR show bilateral basal lucency.

A

alpha 1 antitrypsin deficiency

  • classically results in destruction of lower lobes
  • COPD at young age, COPD with minimal smoking hx, basilar predominant COPD
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4
Q

Most common cause of PNA in cystic fibrosis pts

A

<20: staph aureus

>20: pseudomonas

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5
Q

Light’s Criteria

A

Protein (pleural/serum) >0.5
LDH (pleural/serum) >0.5
Pleural LDH >2/3 ULN serum LDH

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6
Q

Transudative vs exudative

A

Transudative: decreased intrapleural and plasma oncotic pressures or elevated hydrostatic pressure
Exudative: increased capillary or pleural membrane permeability or disruptions to lymphatic outflow

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7
Q

9 year old girl with frequent sinus infections and pneumonia. Vitamin D deficiency. Multiple nasal polyps. Digital clubbing

A

Cystic fibrosis

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8
Q

54 year old man emigrated from Vietnam where he was treated for TB had fatigue, cough with blood-tinged sputum, and 15 pound weight loss. Cavitary lesion present on CT filled with stuff.

A

Chronic pulmonary aspergillosis

  • fungus ball on CT
  • > 3 months of sx (fever, weight loss, cough, hemoptysis)
  • immunocompetent pts with past hx of lung dz have a hard time clearing it
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9
Q

Tachypnea begins shortly after birth and resolves by day 2

A

Transient tachypnea of the newborn

  • inadequate alveolar fluid clearance at birth results in mild pulmonary edema
  • CXR: bilateral perihilar streaking, hyperextended, wet lungs
  • near term infants
  • tx: ppv
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10
Q

Severe respiratory distress and cyanosis after premature birth

A

Respiratory distress syndrome

  • surfactant deficiency results in alveolar collapse and diffuse atelectasis
  • CXR: diffuse, reticulogranular (ground-glass) appearance, air bronchograms, low lung volume
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11
Q

Obstructive pattern (<70%)

  • low DLCO
  • normal DLCO
  • increased DLCO
A
  • emphysema
  • chronic bronchitis, asthma
  • asthma
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12
Q

Restrictive pattern (>70%)

  • low DLCO
  • normal DLCO
  • increased DLCO
A
  • interstitial lung dz, sarcoidosis, asbestosis, heart failue
  • MSK deformity, neuromuscular dz
  • morbid obesity
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13
Q

Normal spirometry

  • low DLCO
  • increased DLCO
A
  • anemia, PE, pulm HTN

- pulmonary hemorrhage, polycythemia

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14
Q

PEEP

A

prevents alveolar collapse and may reopen some already collapsed alveoli

  • improves oxygenation
  • counteracts one of the mechanisms of ARDS
  • if high levels of FiO2 (>60%) are required to maintain oxygenation, PEEP should be increased as well to prevent oxygen toxicity
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15
Q

Premature newborn develops respiratory distress after birth. Is given surfactant and put on mechanical ventilation. Comes of mechanical ventilation but remains hypoxic. Cause?

A

Bronchopulmonary dysplasia

- due to repeated insult to neonatal lungs from mechanical ventilation, prolonged oxygen exposure, and inflammation

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16
Q

pH of pleural fluid

A

normal: 7.6
transudate: 7.4-7.55
exudate: 7.3-7.45
Empyema, tumor, pleuritis, pleural fibrosis: <7.3

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17
Q

Post hemicolectomy, pt develops SOB and unilateral white out on CXR. Mediastinum is shifted towards side of opacification. Pt is a smoker. Most likely cause

A

Atelectasis due to bronchial mucus plug

18
Q

Causes of pleural effusion with high amylase

A
  • pancreatitis

- esophageal rupture

19
Q

Pt with sudden onset of digital clubbing (convex nail beds) and hypertrophic osteoarthropathy (thickening of distal fingers) of wrists and fingers

A

often associated with lung cancer

- get cxr

20
Q

Side effect of tuberculosis

A

primary adrenal insufficiency

  • leads to low aldosterone
  • non-anion gap metabolic acidosis
21
Q

Most common pathogenic organism in children with CF

A

staph aureus

  • cefepime: covers MSSA and pseudomonas
  • vancomycin: covers MRSA
22
Q

COPD acute exacerbation

A

change in

  • cough
  • sputum
  • dyspnea
23
Q

Respiratory distress, confusion, and petechial rash following femur fracture from an ATV accident.

24
Q

Parapneumonic effusions and empyemas fluid findings

A
low glucose (<60)
low pH (<7.2)
25
Pleural effusion with >50,000 lymphocytes
empyema
26
MOA for cromolyn
inhibits mast cell degranulation | - used in exercise induced asthma
27
asthmatics with poorly-controlled disease who are unable to wean themselves from corticosteroids. Pt with productive coughing, mucous plugging (sometimes forming bronchial casts), and hemoptysis
aspergillosis
28
initial tx for nasal polyps
steroid nose spray
29
rheumatologic effusion
exudative with high LDH (>700) and low glucose (<50)
30
why is glucose low in an empyema
high metabolic activity of leukocytes
31
supplemental oxygen in patients with advanced COPD
can worsen hypercapnia - increased dead space causing VQ mismatch - decreased affinity of oxyhemoglobin for CO2 and reduced alveolar ventilation - decreases respiratory drive * the goal oxyhemoglobin saturation is 90-93%
32
What has been shown to prolong survival in COPD patients
long term O2 therapy
33
respiratory distress, confusion, petechial rash after orthopedic surgery
fat embolism
34
hoarseness and multiple finger shaped lesions on vocal cords in a 3 year old
laryngeal papillomas due to recurrent respiratory papillomatosis - caused by HPV 6 and 11 - most likely transmitted vertically
35
Theophylline toxicity
CNS stimulation (HA, insomnia, seizures), GI disturbances (N/V), and cardiac toxicity (arrhythmia)
36
safe FiO2 levels to prevent oxygen toxicity
<60%
37
ARDS
impaired gas exchange, decreased lung compliance. pulmonary htn
38
peritonsillar abscess tx
aspirate and IV Abx
39
TLC in obstructive (asthma) and restictive (obesity) lung disease
obstructive: increased restrictive: decreased
40
method of removing swallowed foreign objects
kids: rigid bronchoscopy adults: flexible bronchoscopy