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Flashcards in Pulmonary Defense Mechanisms Deck (6)
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1
Q

what is kartageners syndrome?

A

ciliary disease with abnl dynein arm

combo of situs inversus, chronic sinusitis, and bronchiectasis

2
Q

what is the role of a macrophage in the inflammatory response in the lung?

A

it suppresses the adaptive immune response

3
Q

what is the most common cell in a bronchoalveolar lavage?

A

macrophage (90-95%)

4
Q

what are the major APC cells in the lungs?

A

dendritic cells

5
Q

Where does the primary immune response occur in the lung?

A

lymph node

6
Q

what type of disease has an increased CD4:CD8 ratio?

A

granulomatous disease (beryllium, sarcoid, TB)