Pulmonary Fibrosis Flashcards Preview

Cases For PACES > Pulmonary Fibrosis > Flashcards

Flashcards in Pulmonary Fibrosis Deck (10)
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1
Q

Clinical signs

A
Central cyanosis, tachypnoea, clubbing
Signs of associated AI disease: rheumatism, SLE
Fine end-inspiratory 'velcro' crackles
Grey skin (amiodarone)
Signs of treatment: cushingoid
2
Q

Bloods for pulmonary fibrosis

A

ANA, RhF, ESR

3
Q

Changes on CXR

A

Reticulonodular shadowing
Loss of definition of heart border
Small lungs

4
Q

ABG signs

A

Type 1 respiratory failure

5
Q

Spirometry findings

A

FEV1/FVC > 0.8 (restrictive)

6
Q

Purpose of bronchoalveolar lavage

A

Done before initiating immunosuppressants to exclude infection
If lymphocytes > neutrophils indicates better prognosis (sarcoidosis)

7
Q

Specific imaging in p fibrosis

A

High resolution CT:
Bibasal subpleural honeycombing - UIP
Widespread ground glass shadowing - interstitial pneumonia typically as part of other AI
Apical - sarcoidosis, TB, ABPA, hypersensitivity pneumonitis, langerhans hystiocytosis

8
Q

Treatments for PF

A

Inflammatory e.g. Interstitial pneumonitis: immunosupression with steroids (steroids with azathioprine no longer indicated)
UIP: pirfenidone (antifibrotic)
N-acetyl cysteine (free radical scavenger)
Single lung transplant

9
Q

Unilateral fine crackles, contralateral normal breath sounds with thoracotomy scar

A

Single lung transplant patient

10
Q

Causes of basal fibrosis

A

Usual interstitial pneumonia (UIP)
Abestosis
CTD
Aspiration