Pulmonary Function Tests Flashcards
Increased lung volumes are associated with _____ diseases such as _____.
obstructive; asthma and emphysema
Loss of muscle function can occur due to _____ or because of ______.
neuropathies; myopathies
Restriction can only be diagnosed by ______.
lung volumes
How is gas transfer measured?
DLCO test
What is IRV?
Inspiratory reserve volume; the volume of gas that can be inhaled above what would normally be inhaled during a tidal breath requiring maximum effort of the respiratory muscles
Diseases that decrease blood in the lung (anemia, pulmonary vascular disease) will ____ CO transfer and result in a ______.
decrease; low diffusing capacity
Examples of neurologic diseases which can reduce respiratory muscle strength (aside from trauma) include: 1) diseases of the motor-neuron endplate (such as myasthenia gravis, botulism, anti-cholinergic poisoning, tick paralysis), 2) diseases of the neuronal axon (Guillan-Barre, critical care neuropathy), or 3) diseases of the nerve root in the anterior horn of the spinal cord (such as ____).
polio, amyotrophic lateral sclerosis
What is Body Plethysmography?
a pulm function test where pt sits inside a pressurized box and very small changes in volume and pressure can be measured
What is TV?
tidal volume; the amount of gas volume moved during a normal inspiration
In a flow volume loop, the fixed obstruction curve will be ______.
flattened in both inspiration and expiration
This is the maximum intra-thoracic pressure is measured when the patient attempts to inspire as forcefully as possible against an occluded airway (Mueller maneuver) while at residual volume.
Pi max
What is DLCO?
diffusion capacity of the lung using a small amount of CO
What 2 tests assess lung muscle function?
- Pi max 2. Pe max
Pulmonary fibrosis, a restrictive disease, is characterized by stiff lungs and a _____ pressure-volume (P-V) curve.
flat
What is Pi max?
The maximum intra-thoracic pressure is measured when the patient attempts to inspire as forcefully as possible against an occluded airway (Mueller maneuver) while at residual volume
This is the volume of gas in the lung even after maximal exhalation- cannot be measured with spirometry.
Residual volume (RV)
Examples of neurologic diseases which can reduce respiratory muscle strength (aside from trauma) include: 1) diseases of the motor-neuron endplate (such as myasthenia gravis, botulism, anti-cholinergic poisoning, tick paralysis), 2) diseases of the neuronal axon (such as ______), or 3) diseases of the nerve root in the anterior horn of the spinal cord (polio, amyotrophic lateral sclerosis).
Guillan-Barre, critical care neuropathy
Examples of ______ which can reduce respiratory muscle strength (aside from trauma) include: 1) diseases of the motor-neuron endplate (myasthenia gravis, botulism, anti-cholinergic poisoning, tick paralysis), 2) diseases of the neuronal axon (Guillan-Barre, critical care neuropathy), or 3) diseases of the nerve root in the anterior horn of the spinal cord (polio, amyotrophic lateral sclerosis).
neurologic diseases
Decreased lung volumes are diagnostic of _____.
restrictive processes
In a flow volume loop, the airflow is decreased with coving of the expiratory flow loop, a hallmark sign of ______ lung disease.
obstructive
Muscle abnormalities can occur due to _____ (steroid myopathy), _______ (polymyositis, dermatomyositis), or ______ (Lambert-Eaton myasthenic syndrome), among others.
- drugs
- collagen vascular diseases
- paraneoplastic syndromes
What is FRC?
Functional residual capacity; RV + ERV; amount of gas left in the lung after normal expiration; the point at which the respiratory system is in equilibrium
What diseases or conditions can increase DLCO?
- Polycythemia
- early CHF
- asthma
- alveolar hemorrhage
This is the volume of gas that can be inhaled above what would normally be inhaled during a tidal breath requiring maximum effort of the respiratory muscles.
Inspiratory reserve volume (IRV)
In a flow volume loop, _______ will have a compressed airway during expiration with a normal inspiratory loop curve.
variable intra-thoracic obstruction
A ______ measures the compliance of the lung.
P-V curve
What is the sum of all the lung volumes called?
total lung capacity (TLC)
What causes a fixed obstruction?
circumferential lesions from tracheal stenosis, prior intubation, circumferential airway neoplasm
Muscle abnormalities can occur due to drugs (such as _____), collagen vascular diseases (______), or paraneoplastic syndromes (_______), among others.
steroid myopathy polymyositis, dermatomyositis Lambert-Eaton myasthenic syndrome
In a flow volume loop in the case of ______, the maximal airflow is reduced because the total volume of gas in the lung is reduced.
restrictive diseases