Pulmonology Flashcards

1
Q

Indications for PFTs

A
  • Dx and classify severity of pulm dysfxn
  • Distinguish btn; obstructive, restrictive or mixed pulm dz
  • Monitor response to therapeutic interventions
  • Determine pulmonary risk prior to surgery
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2
Q

Basic PFTs

A
  • Air flow spirometry
  • Lung volumes
  • DLCO
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3
Q

Considerations for PFTs

A
Age
Height
Weight
Gender
Ethnicity
Smoking
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4
Q

How many times must spirometry testing be done

A

three times

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5
Q

FEV-1/FVC ratio for obstructive pattern

A

below seventy percent

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6
Q

Why is bronchodilator testing done

A

To test reversibility

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7
Q

How long after nebulizer or inhaler is PFT done again

A

15 min

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8
Q

What is the indication for reversibility

A

Increase in FEV1 by twelve percent or t200ml

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9
Q

DLCO

A

Measures ability of lungs to transfer CO and saturate Hgb

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10
Q

DLCO for healthy lung

A

Little CO collected after expiration (mostly absorbed)

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11
Q

Gold std diagnostic for COPD

A

Reversibility below twelve precent on spirometry

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12
Q

How often do you do asthma follow up

A

one to three months initially then three to twelve months depending on severity

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13
Q

In what age is spirometry not beneficial

A

Five and under

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14
Q

How long after an acute asthma exacerbation does an individual need to follow up

A

one week

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15
Q

What is the 3rd leading cause of death in the US

A

COPD

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16
Q

Chronic bronchitis

A

cough for three months during two consecutive yrs

17
Q

structural changes w/ chronic bronchitis

A

Mucous gland enlargement; hyper secretion
Bronchial squamous metaplasia
Loss of ciliary transport

18
Q

What cells are predominant in the inflammation associated with chronic bronchitis

A

Neutrophils

19
Q

What cells are predominant in the inflammation associated with asthma

A

Eosinophils

20
Q

Is the airflow obstruction in chronic bronchitis inspiratory or expiratory

A

Both

21
Q

Which causes more parenchymal damage; Emphysema or COPD

A

Emphysema

22
Q

Is the airflow obstruction in emphysema inspiratory or expiratory

A

Expiratory

23
Q

What DLCO is associated with emphysema

A

Reduced (destruction of capillary bed)

24
Q

What is the role of antitrypsin

A

Inhibit elastase

25
Q

What is the role of elastase

A

Break down elastin which reduces the elasticity of the lung alveoli

26
Q

How does smoking affect the lungs

A

It activates elastase which causes degeneration of alveolar elastin

27
Q

How is pursed breathing an adaptation in COPD

A

it increases the intrabronchial pressure to keep the bronchi open and more air can be expelle

28
Q

Causative agent of pneumonia in younger pple

A

Chlamydophila

29
Q

Causative agent of pneumonia associated w/ diarrhea and in elderly

A

Legionella

30
Q

Causative agent of pneumonia in CHF

A

Pseudomonas

31
Q

Post influenza causative agent of pneumonia

A

Staph aureus