Pulmonology Flashcards

(36 cards)

1
Q

what are common etiologies of bronchiolitis?

A

viral - RSV, influenza, parainfluenza, metapneumovirus

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2
Q

what is the presentation of bronchiolitis?

A

apnea (esp. in 4 months of age -RSV)

copious rhinorrhea

cough/wheeze

fever

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3
Q

how do you diagnose bronchiolitis?

A

PE findings and history

x-ray unecessary

specific cause can be confirmed by antigen testing or PCR?

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4
Q

what’s the most common cause of bronchiolitis?

A

RSV

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5
Q

how do you manage bronchiolitis?

A

supportive care - nasal suction, hydration, supplemental O2 if sats<90% on room air

meds - trial of beta 2 agonist or racemic epinephrine (works, keep it up), nebulized 3% hypertonic saline

no benefit to chest PT

screen for RSV to avoid abx and isolate infants in hospitals

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6
Q

what are the sequelae of bronchiolitis?

A

obstruction of the u and l respiratory tract that can lead to respiratory failure

  • highest risk in premies and those with lung disease
  • give these babies Synagis
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7
Q

What is Synagis?

A

Palivizumab

IgG monoclonal Ab

<29 weeks gestation, younger than a year at onset of RSV season

chronic lung dz less than 24 years

*consider in immunocompromised, CV disease, neuromuscular disease

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8
Q

what are the causes of respiratory failure in infants?

A

upper airway ob

lower airway ob

sepsis

hypotonia

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9
Q

what presentations in infants is concerning for impending respiratory failure?

A

inreased accessory muscle use

inability to coordinate feeding (poop out)

decreased arousability

hypoxemia/hypercarbia

*normal PCO2 with marked tachypnea very poor sign

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10
Q

what are the three phases of pertussis and the clinical features of each?

A
  1. catarrhal: cough and rhinorrhea (1-2 weeks)
  2. paroxysmal: fits of coughing, inspiratory whoop, post-tussive emesis (2-8 weeks)
  3. convalescent - gradual waning of symptoms (weeks to months)

Generally, NO FEVER

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11
Q

what is the incubation period for pertussis?

A

7-10 days

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12
Q

how is diagnosis of pertussis made?

A

clinical - paroxysmal cough, whoop, post-tussive emesis

lymphocytosis is a clue

PCR and culture

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13
Q

what is the treatment for pertussis?

A

macrolides

azithromycin (5 days)

preferred in young, pregnant women

alternatives: erythromycin (14 days), clarithromycin (7 days), TMP-SMX (14 days)

*prevents spread and limits cough in catrarrhal

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14
Q

what are the complications of pertussis?

A

abx don’t do much

hospitalization

apnea

2ndary pneumonia

seizure

death

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15
Q

what is the most common source in infant pertussis?

A

family members

one of the reasons we have been moving to immunizing mother during pregnancy

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16
Q

what are the clinical manifestations of pneumonia by age?

A

neonates - fever or hypoxia only

young infants - apnea may be first sign

children - fever, chills, tachypnea, cough, malaise, retractions, apprehension

17
Q

which type of pneumonia usually presents with high fever, chills, and focal findings?

18
Q

what type of pneumonia presents with diffuse crackles?

19
Q

what are the most common causative organisms for pneumonia by age?

20
Q

in longstanding asthma, what may occur?

A

remodeling of the airway that can lead to incomplete reversability

21
Q

what’s a common clinical sign of childhood asthma?

A

post-tussive emesis (night or early morning)

22
Q

when do peds usually diagnose with asthma?

A

after recurrent episodes

usually 4

partially reversible measured by spirometry increase of FEV 1 > 200 mL AND 12% from baseline after SABA admin.

23
Q

using metered dose inhaler without a spacer can cause loss of up to how much of the medicine?

24
Q

how often should children have spirometry once the asthma is under control?

A

every 1-2 years

25
what's an unusual asthma trigger?
essential oil infusers
26
what percentage of children with asthma have an allergic phenotype?
60-80%
27
what happens during exercise induced bronchospasm?
airway dries out, and bronchospasm ensues from inflammation
28
what do you need to know to determine asthma severity?
symptoms nighttime awakenings SABA use for rescue interference with normal activities PFTs
29
what is the preferred approach to initiate controller therapy in pediatric asthma?
inhaled cortiocosteroids if already on SABA add LABA to ICS if not well controlled leukotriene alternative (good for allergic)
30
what are the components of an asthma action plan?
green - daily regimen yellow - acute loss of asthma control (nip exacerbation in the bud) red - ER
31
what are the highest risks for severe asthma exacerbations?
poor asthma control higher disease severity prior hospitalizations/intubations non-adherence to therapy
32
what is status asthmaticus?
no response to reptitive or continuous administration of SABA
33
what are third tier therapies for asthma?
IV ketamine inhaled anesthetics ECMO
34
what are 2nd tier asthma exacterbation treatments?
IV magnesium aminophylline salbutamol non-invasive ventilation heliox
35
what are 1st tier asthma exacerbation treatments?
inhaled Beta agonists inhaled anti-cholinergics systemic corticosteroids
36