PURPLE - Key Members

Question 1

What antibiotics are part of Augmentin?

Answer 1

amoxicillin (aminopenicillin) + clavulanic acid (B-lactamase inhibitor)

Question 2

(Piperacillin/Nafcillin) _____ is a penicillinase-resistant used for very severe methicillin-susceptible Staphylococcus aureus infections such as endocarditis, cellulitis, and sepsis.

Answer 2

Nafcillin

Question 3

____ is a narrow spectrum beta-lactam that is used against most gram positive bacteria, given parenterally. It can also cause hypersensitivity reactions.

Answer 3

Pencillin G

Question 4

The first-line antibiotic for Listeria monocytogenes is ____/____, both classified as ______

Answer 4

ampicillin/amoxicillin

classified as aminopenicillins

Question 5

Clavulanic Acid, Sulbactam, tazobactam are ____ often added to penicillin antibiotics to protect them.

Answer 5

Beta-lactamase inhibitors

Question 6

A 17-year-old boy presents to the emergency department with new-onset burning sensation, redness, and swelling of his face, neck, and arms. The patient had been enjoying the warm and sunny weather by playing football on the beach with his friends for the past 45 minutes, after which one friend pointed out the redness and swelling of the patient’s face. The patient notes he had visited his dermatologist last week and started a new medication that would help the “pimples on his face” go away. Examination shows that the temperature is 37℃ (98.6℉), blood pressure is 118/75 mm Hg, pulse is 60/min, and respirations are 15/min. Head and neck examination shows erythema, open and closed comedones, edema, and vesicles on the face, neck, and arms. Oral examination does not reveal lesions. Which of the following most likely explains his condition?

A. contact dermatitis
B. Doxycycline side effect
C. Stevens-Johnson syndrome
D. Erythromycin side effect

Answer 6

B. doxycycline

Doxycycline is part of tetracycline-class antibiotics and are phototoxic. Symptoms of phototoxic drug eruptions usually present after a shorter duration of sun exposure compared to the duration of exposure seen in a typical sunburn

Question 7

This tetracycline is not used as an antibiotic, but acts as an ADH antagonist.

Answer 7

demeclocycline

Question 8

_____ is a macrolide antibiotic that also acts a Motilin agonist, thereby stimulating intestinal peristalsis.

Answer 8

Erythromycin

Question 9

Azithromycin is often co-administered with ____ for Gonorrhea.

Answer 9

Ceftriaxone

Question 10

_____ are a class of antibiotics that increase the serum concentration of theophylline and oral anticoagulants.

Answer 10

Macrolide - inhibit Cytochrome P540 enzyme