Pyoderma, Fungal Skin Diseases, Normergic Dermatitis Flashcards

1
Q

Pyoderma types

A
  1. Surface pyoderma (epidermis)
  2. Superficial pyoderma (follicle involvement)
  3. Deep pyoderma (deep dermis)
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2
Q

Pyoderma causes

A
🔺Usually caused by:
- coagulase positive staphylococci: 
* Staphylococcus pseudintermedius 
* Staphylococcus aureus 
* Staphylococcus schleiferi 
- coagulase negative staphylococci 
- micrococci
🔺Less frequently by:
- alpha-hemolysing streptococci
- Gram negative rods: Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli
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3
Q

Surface pyoderma - form, treatment, cause

A
  • form: hot spot/intertrigo
  • ab: topical
  • underlying disease: Flea Allergic Dermatitis (FAD), skin folds (humid)
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4
Q

Superficial pyoderma - form, treatment, cause

A
  • form: impetigo, supf. folliculitis
  • -> most common form
  • ab: topical may be enough in mild cases + systemic treatment may be necessary aswell, 3 weeks cephalexin (no sens test needed - if unresponsive -> sensitivity test) (we treat until clinical cure, then an additional week)
  • underlying disease: atopic dermatitis (AD) and FA food allergy
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5
Q

Deep pyoderma - form, treatment, cause

A
  • form: furunculosis cellulitis (the deeper layers of the skin or even underlying tissues affected. Associated with general signs aswell (bacteremia). Bloody pus may be seen)
  • ab: topical + systemic - sensitivity test is required!!) we treat until clinical cure, then an additional 2-3w.
  • underlying disease: demodicosis
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6
Q

Acute moist dermatitis, pyotraumatic dermatitis, hot spot - cause, treatment

A

A type of surface pyo - Involves the superficial horny layer (str. corneum)
🔺 any (long haired) breeds + hot, humid weather
🔺 self trauma perpetuates the problem: (itch-lick-chew cycle)
🔺 lesions develop rapidly
🔺 several underlying causes (e.g. flea, otitis, paraproctitis, neurosis)
🔺 Treatment: eliminate the underlying cause!
+ clipping, shampoos (disinfacting, drying) short term CS + antibiotics topically
(parenterally)
–> This is the only type where we can use cortison short term to stop the itching and licking!

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7
Q

Skin fold pyoderma (intertrigo) - cause, treatment

A
(Surface pyo type)
🔺 anatomical „defects”: warm+humid + dark microenvironment + self-trauma
🔺 Types: 
- lip fold: c. spaniels
- facial fold: brachycephalic breeds
- vulvar fold pyoderma: obese, too early
spayed bitches (small vulva in tucked up position)
- tail fold pyoderma: corkscrew tail 
- body fold pyoderma
- generalized: shar-pei 
🔺 Treatment: plastic surgary or
everyday cleansing by disinfectant, drying powder, solutions, suspensions, shampoos (benzoil-peroxid)
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8
Q

Impetigo

A

A type of supf pyo. Aka juvenile pustular dermatitis, puppy pyoderma, nonfollicular pustule.
* subcorneal (beneath str corneum) pyoderma: on the face, ventral abdomen, and axilla pustules, papules, and yellow crusts
* young puppies prior to puberty
* may be asymptomatic
* underlying problems: ectoparasites, endoparasites
poor nutrition, unhygienic environment
* Treatment: treat the underlying cause,
+ antibacterial shampoos (ethyl-lactate, chlorhexidine,(benzoyl peroxide) in every 2-4 days
for 2 weeks, then +/- antibiotics (but NO Corticosteroids!!! May cause skin atrophy according to source)

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9
Q

Superficial folliculitis

A

A type of supf pyo.

  • bacterial infection at the level of the intact hair follicle or at the epidermis immediately below the str. corneum
  • any age, but more common in young dogs
  • variable lesions: papules, pustules with hair protruding, crusts, epidermal collarettes(similar to ringwork, pemphigus 1st phase), “moth-eaten” alopecia +/- pruritus
  • IT IS ALWAYS SECONDARY PROBLEM (atopy, FA, parasites, endocrine disorders, immunosuppression, etc.)
  • Treatment: underlying cause, antibacterial drugs for min 3 weeks systematicly, + topically (but NO Corticosteroids!!! Suppr. Immune system)
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10
Q

Deep pyoderma - definition, cause

A

Bacterial infection of the skin beneath the hair follicle involving both dermal and subcuticular tissues, leading to rupture of the follicle and development of furunculosis (deep infection of the hair follicle leading to abscess formation) and cellulitis(inflamm of deeper layers).

  • Staphylococcus pseudintermedius +/- other bacteria (Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli)
    + underlying cause ALWAYS present (demodicosis!!!, foreign body, dermatophyte/ringworm infection, endocrine disorder, immunodeficiency, CSs)
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11
Q

muzzle, chin folliculitis and furunculosis (canine acne)

A

A type of deep pyoderma.
- Great danes, boxers, Dobermann, Hungarian Vizsla
- Treatment: systemic antibacterial drugs + topical
(Demodicosis!! 2-3m ab)

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12
Q

nasal pyoderma

A

A type of deep pyo.
- dolichocephalic breeds (long nose) german shepard eg.
- Treatment: antibiotica 6+x+2weeks, Elisabethan collar
(6w or until treated then additionally 2w?)
Eg. Case: trauma, typically short haired dog. Ointment treatment may be enough.

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13
Q

Necrotizing dermatitis

A

Eg. Here caused by deep pyo - streptococcus infection. Full recovery after AB treatment!
(Neck skin gone)

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14
Q

Interdigital pyoderma (pododermatitis)

A

🔺short coated breeds
🔺Underlying factors: e.g.: foreign body, Demodex, atopy, trauma
🔺Clinical signs: The feet may be swollen, painful, discharged pus, alopecia due to licking, paronychia;
In chronic cases: nodules, ulceration, fistulae, furunculosis
🔺Treatment: treat the underlying cause, surgical drainage, bathing the feet in saline, systemic antibact. therapy autogenous vaccines, immunestim. (?) e.g. levamisole

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15
Q

Pressure point pyoderma (callus pyoderma)

A

A type of deep pyo.
🔺Occurrence: large breed dogs: elbows, hocks, sternum
🔺The skin thickens, then if repeated trauma: deep pyoderma
🔺Treatment: antibacterial drugs, + check for underlying problems (soft bed - trauma)

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16
Q

Furuncolosis

A

deep infection of the hair follicle leading to abscess formation as a consequence of deep pyoderma.
- casues: lick granuloma, callus pyoderma,
pyotraumatic folliculitis (trauma!!!)
- mostly due to psychogenic casue (lick), but allergy… aswell.
- treatment - treat the deep pyo (and prevent licking!!)

17
Q

GS pyoderma

A

(I think?) Pyoderma gangrenosum (PG) is an uncommon, neutrophilic inflammatory skin condition, which classically presents as a painful nodule, plaque, or pustule that enlarges and breaks down to form a progressively enlarging ulcer with raised, undermined, violaceous borders and a surrounding zone of erythema.)
Lesions:
papules, pustules, furunculosis, hyperpigmentation, alopecia
Localization:
gluteal region, ventral abdomen, dorsum, thighs (generalized)

18
Q

Pyotraumatic folliculitis

A

Deep pyo type. Trauma caused folliculitis.
golden/labrador retrievers, St. Bernards, rottweiler
mimics acute moist dermatitis (surface derm - here deeper!)
no response on cleansing and CS-therapy - need systemic!! (We first think its surface derm?)

19
Q

Generalized deep folliculitis, furunculosis and cellulitis

A
  • This is the most severe type of deep pyoderma
  • Underlying factors are present!
  • The lesions occur anywhere but especially
    pronounced on the trunk and ventral abdomen
  • Treatment: very long antibacterial therapy (iv!!!),
    + whirlpool bathing + immunostimulation+ underlying factors must be treated
    (Bathing - like a boblebad with iodine, moving water better effect)
20
Q

CELLULITIS demodicosis + AD

A

Cause: immundeffect, hypothyreoidism, (iatrogen) Cushing-disease,

21
Q

Ddx deep pyo

A

Juvenile pustular dermatitis

juvenile cellulitis

22
Q

List the types of fungal skin diseases

A
  1. Superficial mycoses
  2. Subcutaneous mycoses
  3. Systemic mycoses
23
Q

List possible types of superficial mycoses

A
  • Dermatophytosis (ringworm)
  • Microsporiasis
  • Malassezia pachydermatis (yeast)
24
Q

Dermatophytosis (ringworm)

A
  • dogs and cats
  • Etiology.: Microsporum canis, M. gypseum, M. persicolor
    Trichophyton mentagrophytes, T. verrucosum, T. terrestre
  • direct contact/contaminated materials from the environment
  • Clinical signs:
    Dogs: patchy alopecia, plaques, folliculitis, scales, crusts, (nails) Cats: ‘cigarette-ash’-like, patchy alopecia, miliary dermatitis, crusts,
    Can be ASYMPTOMATIC! And/or LESIONS ON THE OWNER!
  • Self limiting disease in healthy animals (lack of immunity?)
    • Diagnosis: most accurate diagnosis: culturing !!!
    (dermatophyte test medium (DTM))
    • (Wood’s lamp, KOH preparations by microscopy, biopsy (PAS staining)
  • Treatment: see in the first lecture
25
Q

Malassezia pachydermatis (Pityrosporum canis)

A
  • normal flora of the ears –> otitis externa
  • usually secondary to: allergodermatitis,
    endocrinopathies, etc.
  • rarely generalized dermatosis by itself: alopecia,
    scaling, pruritic –> seborrhoea, lichenification
  • Diagnosis: cytology (Diff-Quick staining)
    (IF microscopy, culture – sample in test medium to send)
  • Treatment: see in the first lecture
26
Q

Normergic dermatitis - list the types

A
  • Primary irritant contact dermatitis
  • nasal solar dermatitis
  • burns
  • frost bite
27
Q

Primary irritant contact dermatitis

A
  • Physical or chemical cause.
  • Primary irritant contact aka dermatitis (normergic dermatitis)
  • Must be differentiated from contact hypersensitivity
  • More common than contact hypersensitivity
    🔺 Etiology:
  • acids and alkalis: absolute cause
  • detergents, soaps, solvents: relative cause
  • flea collars ( fitted too tightly); can be allergic, as well
    🔺 Clinical signs: localization: any area where the hair is sparse ventral surface of the abdomen, axilla, intertdigiatal space, perineum, scrotum
    🔺 Treatment:
  • find the irritating substance and remove it,
  • bathing,
  • topical CS-ointments
28
Q

Nasal solar dermatitis

A

(collie-nose dermatitis= DLE=discoid lupus erythematosus)
* Cause: unknown, collies are predisposed,
phototoxic reaction to ultraviolet radiation;
Seasonal occurrence in the early stages with increasing severity by the time going
* Localization: in unpigmented skin nose (eyelids, lips)
* Clinical signs: erytherma, alopecia around the nose, crusting, ulceration, exudation
(risk! squamous cell carcinoma)
* Treatment: avoid sunlight, use topical GC,
and PABA-containing(UVB filter) sunscreen agents

29
Q

Burns

A
  • Types: full-thickness: destruction of the epidermis + adnexa
  • partial thickness: reepithalization is possible secondary pyoderma is common
  • Clinical signs: pain, skin over the affected area becomes dry and hard; sec. infections
    If necrosis is on > 25 % of the body surface: systemic illness * Treatment: remove necrotic tisue, gentle bathing and cleaning, hydrating, pain killer, AB, hepatic support
    For burn: hydrogel, hydrocolloids Calcium alginate swab („Nobaalgin”) - moist healing environment!
30
Q

Frost bite

A
  • Occurrence: rare, - 30 C for prolonged times
  • Commonest sites: tips of the tail, ears, scrotum, toes
  • Treatment: thaw rapidly in warm water, topical antibact creams, surgical debridement