Qbank1 Flashcards

(64 cards)

1
Q

Osteoporosis, investigation

A

Diagnosis -
postmenopausal/men >50yrs
+ fracture

Scoring-
DXA
Garvan fracture risk indicator

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2
Q

Osteoporosis, treatment

A

Low risk without fracture -
falls reduction
exercise
diet, no smoking, no alcohol
education and support

The rest:
Bisphosphonates
Denosumab (rank ligand inhibitors)
Oestrogen replacement
Strontium ranelate (antiosteoporotic agent)

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3
Q

Triad for primary adrenal crisis

A

Low serum sodium
Low serum glucose
High serum potaaaium

  • consider diagnosis in unexplained severe dehydration or shock
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4
Q

Adrenal crisis, management

A

Investigation
Cortisol
ACTH
17 hydroxyprogesterone
Plasma renin activity
Urinary steroid and sodium
serum pH, electrolytes and glucose

Treatment
1. steroid replacement - hydrocortisone, fludrocortisone
(glucocorticoid if mild or moderate)
2. IV fluids
3. Dextrose
4. Electrolyte adjustments
5. Treat trigger

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5
Q

SINBAD clasification system

A
  • All other characteristics are scored 0
  • > 3 severe ulceration

Score of 1 each
SITE - Midfoot and hindfoot
ISCHAEMIA - Clinically reduced pedal blood flow
NEUROPATHY - Sensation lost
BACTERIAL INFECTION - Present
AREA - > 1cm
DEPTH - Reaching muscle / tendon or deeper

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6
Q

Diabetic foot ulcer antibiotics

A

NONE
- just debridement and dressing

MILD
- Flucloxacillin,
- Mod Pen allergy(Cefalexin)
- Severe Pen allergy (Clindamycin)

MODERATE
- Flucloxacillin + Metronidazole
- Mod pen allergy (Cefazolin/Cefalexin + Metronidazole)
- Severe pen allergy (Clindamycin)

SEVERE
- Amoxicillin Clavulanic Acid / Piptaz
- Mod pen allergy (Cefepime + Metronidazole)
- Severe pen allergy (Clindamycin + Ciprofloxacin)

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7
Q

Pheochromocytoma triad

A

Episodic headache, sweating, and tachycardia.

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8
Q

Thyroxine dose adjustments

A

Halflife of 7-10 days
Initial doses increased every 3-4 weeks
Full benefit 3-4 months

Monitoring every 4-6 weeks until near euthyroid

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9
Q

Nipple discharge differentials

A

MILKY - medications, hyperprolactinemia (adenoma, etc)

MULTICOLORED - duct ectasia, comedomastitis

PURULENT - mastitis, abscess

WATERY SEROUS/BLOODY - intraductal papilloma, malignancy, premalignant lesion

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10
Q

Nipple discharge differentials

A

MILKY - medications, hyperprolactinemia (adenoma, etc)

MULTICOLORED - duct ectasia, comedomastitis

PURULENT - mastitis, abscess

WATERY SEROUS/BLOODY - intraductal papilloma, malignancy, premalignant lesion

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11
Q

Renal artery stenosis, referral criteria

A

Category 1 (<30 days)
Confirmed RAS + worsening renal function/hypertension

Category 2 (<90 days)
Incidental RAS of >60%

Category 3 (<365 days)
None

Requirements
History
UE
Renal USS

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12
Q

Acute coronary syndrome, initial management

A

IF OUTPATIENT:
1. Refer via ambulance for assessment
2. Aspirin
3. Sublingual GTN

IF A AND E:
1. ECG (q15 mins)
2. Biomarkers (cardiac troponin)
3. obtain Chest x-ray (old/new record)
4. Morphine if with ongoing chest pain
5. Oxygen if <93% or <88%
6. GTN if with ongoing chest pain
7. Aspirin

  • If ECG is negative then repeat assessment for other life threatening causes
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13
Q

Acute coronary syndrome, high risk features of chest pain

A

Refer if with any of the following:
1. ongoing/repetitive chest pain after treatment
2. elevated troponin
3. persistent ST depression/T wave inversion
4. ST elevation (>2 leads)
5. Haemodynamic compromise
6. sustained ventricular tachycardia
7. syncope
8. known LV Ejection fraction (<40%)
9. prior ACS

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14
Q

Acute coronary syndrome, treatment

A
  1. GOLD STANDARD
    PCI
  2. < 12 hrs from onset, PCI not available
    FIBRINOLYTICS (tenecteplase, alteplase, streptokinase)
    +
    ANTITHROMBIN (enoxaparin, heparin)
    +
    ANTIPLATELET (clopidogrel)
    THEN
    Coronary Angiography
  3. Failed fibrinolysis
    PCI
  4. > 12 hrs from onset but still with chest pain
    PCI
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15
Q

Hypertension, measurement methods

A

INITIAL/CVD RISK CALCULATORS
Clinic blood pressure >140/90

CONFIRMATORY
Ambulatory blood presure
Home monitioring

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16
Q

Hypertension, treatment targets

A

TREATMENT INITIATED AT:
Low absolute CVD risk >160/90mmHg

Moderate absolute CVD risk
>140/90mmHg

TREATMENT GOALS:
Uncomplicated hypertension
<140/90mmHg

CKD
<140/90mmHg

High cardiovascular risk
<120/90mmHg

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17
Q

Hypertension, initial medications

A

Uncomplicated:
1. ACEI - captopril, enalapril, etc
2. ARB - losartan, candesartan, etc
3. Calcium channel blockers - veralpamil, diltiazem, nifedipine, etc
4. Thiazide diuretics - hydrochlorothiazide, indapamide

  • ACEI + ARB = Increased side effects

Specific conditions
1. CKD + Albuminuria - ACEI, ARB
2. MI - ACEI, Beta blocker
3. Symtomatic Angina - BB, CCB
4. CHF - ACEI, BB
5. Intolerant to ACEI - ARB

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18
Q

Rate control drugs

A

Amiodarone
Dronedarone

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19
Q

Rhythm control drugs

A

BB
CCB
Digoxin

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20
Q

Heart failure, basic investigation

A

ECG
Chest x-ray
Transthoracic echocardiogram

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21
Q

Acute heart failure, management

A

Oxygen - <94% O2 sat
Ventilation - persistent shortness of breath
Loop diuretics - acute heart failure
Vasodilators - >90mmHg SBP
Inotropes - Hypoperfusion

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22
Q

Chronic heart failure, management

A

ACEI: LV EF <49%
Beta Blocker: LV EF <49%
- bisoprolol, carvedilol, metoprolol, nebivolol
Mineralocorticoid receptor antagonist: LV EF <49%
Diuretics: congestion
Cardiac resynchronisation therapy
Implantable cardioverter defibrillators
Pressure monitoring
Surgery

2nd option after ACEI: ARB, ARNI, Ivabradine, Hydralazine, Digoxin, Nutraceuticals

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23
Q

Pericarditis, presentation

A

Most common symptom: sharp, piercing chest pain in the centre or left side of the chest.

Others:
low fever
heart palpitations
shortness of breath
weakness or fatigue
nausea
dry cough
swelling of the legs or abdomen

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24
Q

Pericarditis, management

A

INVESTIGATION:
ECG
Chest x-ray
Optional: Echocardiogram, CT scan, MRI

MEDICATION:
NSAID
Colchicine
Pain -relief

Optional: Anitibiotics (causes are usual idiopathic)

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25
Acute limb ischemia, investigation
DSA, CTA, DUS, and CE-MRA - CT angiography is 1st line - DSA is gold standard Myoglobin and creatinine kinase to assess prognosis and treatment
26
Acute limb ischemia, Initial treatment
Initial medical treatment analgesia unfractionated heparin (UFH) refer to specialist for further management
27
Superior vena cava syndrome, management
*avoid biopsies due to bleeding risk Required diagnostic tests Chest x-ray Management if cancer related SVC bronchoscopy with washing sputum cytology limited biopsy local radiation antineoplastic agents anticoagulant or fibrinolytic therapy diuretics steroids
28
Bleeding parameter monitoring
aPTT - heparin BT - platelet function INR - warfarin
29
Indications for AAA repair
Male with AAA >5.5 cm Female with AAA >5.0 cm Rapid growth >1.0 cm/year Symptomatic AAA (abdominal/back pain/tenderness, distal embolisation)
30
Supraventricular tachycardia, management
Unstable - DC cardioversion Stable - Vagal manoeuveres - Adenosine (avoid in asthma) - Verapamil (avoid in <1 yr) Maintenance (as needed) - Propanolol - Diltiazem
31
ECG heart rate estimation
300/Big squares between R-R = HR Estimate by Big square: 1 = 300 2 = 150 3 = 100 4 = 75 5 = 60 If with arrhythmia Rs in 6 seconds x 10
32
Kussmaul's sign causes
* dropped JVP during expiration and rise in inspiration (normal is reverse) restrictive cardiomyopathy constrictive pericarditis cardiac tamponade
33
Kussmaul's sign causes
* dropped JVP during expiration and rise in inspiration (normal is reverse) restrictive cardiomyopathy constrictive pericarditis cardiac tamponade
34
Acute pulmonary oedema, investigation
ECG Chest x-ray troponin/BNP Blood test; UE, LFT, Glucose, UA, FBE, ABG Echocardiogram
35
Acute pulmonary oedema, management
Sitting position Oxygen via Hudson type mask amd reservoir/CPAP/BiPAP Glyceril trinitrate - reduce preload Furosemide Morphine - reduce preload
36
Jelly fish sting management
Bluebottle and minor jellyfish - single sting Wash sting site with seawater and remove tentacles Hot water immersion (45°C for 20 mins) Major box jellyfish - multiple stings Apply vinegar and remove tentacles Commence immediate cardiopulmonary resuscitation on any patient who is unconscious - analgesics and referral, consider antivenom
37
Tetanus prophylaxis for wound management
TIG - Dirty wound + Uncertain vaccination history Tetanus vaccine: Dirty wound + >5 yrs last vaccine Clean/minor wound + >10 yrs last vaccine Uncertain vaccination history DTPa - <10yrs old dTpa - 10-18 yrs old dT - >18 yrs old
38
Cushing's triad
Hypertension Bradycardia Irregular breathing - phenomenon in response to increased ICP
39
Shingles management
Investigation PCR (optional) Management Antiviral (famciclovir, aciclovir, valaciclovir) - CNS, zoster ophthalmicus, disseminated, immunocompromised Ongoing pain relief - Paracetamol, Prednisone, Amitriptyline, Oxycodone additional options for Postherpetic neuralgia - gabapentin, pregabalin, topical capsaicin, TENS
40
Acne classification
Mild - primarily noninflammatory Moderate - both noninflammatory and inflammatory, a few pustules Severe - numerous nodules and cysts
41
Acne treatment, mild
Mild 1st line comedonal - TR 1st line papule - TR + BPO, BPO, topical AB 2nd line - salicylic acid TR - topical retinoid BPO - benzoyl peroxide AB - antibiotics
42
Acne treatment, Moderate
Moderate 1st line - BPO/ topical AB, BPO + TR 2nd line - add Hormones BPO - benzoyl AB - antibiotics TR - topical retinoid
43
Acne treatment, Severe
Severe 1st line - Oral isotretinoin 2nd line - Oral AB + TR + BPO, BPO/topical AB Maintenance - add hormones AB - antibiotic TR - tropical retinoin BPO - benzoyl peroxide
44
Alopecia areata, management
1st line child: topical high potency steroid adult: intralesional corticosteroid injection 2nd line topical immunotherapy Severe cases: rapid progressive, diffuse, extensive, alopecia totalis, alopecia universalis 1st line : systemic treament, topical corticosteroid, topical minoxidil, topical immunotherapy 2nd line: combine 2 or 3 topicals
45
Melanoma risk factors greatest to least
x10 previous melanoma x7 multiple melanotic nevi x6 multiple dysplastic nevi x4 previous other skin cancer x2 1st degree family melanoma x2 fair complexion x1.5 UV exposure
46
First surveillance interval following removal of low risk conventional adenomas only
Low-risk individuals – conventional adenomas Interval of 10 years *low-risk conventional adenomas only (1–2 small [<10mm] tubular adenomas without high-grade dysplasia).
47
First surveillance interval following removal of high risk conventional adenomas
Interval of 5 years: • 1–2 tubular adenomas with HGD or tubulovillous or villous adenomas, all of which are <10mm • 3–4 tubular adenomas without HGD, all of which are <10mm. Interval of 3 years: • 1–2 tubular adenomas with HGD or tubulovillous or villous adenomas (with or without HGD), some are ≥10mm • 3–4 tubular adenomas, some are ≥10mm • 3–4 tubulovillous and/or villous adenomas and/or HGD, all <10mm.
48
First surveillance interval following removal of ≥5 conventional adenomas only
5–9 adenomas, intervals are • 3 years if all tubular adenomas <10mm without high grade dysplasia (HGD) • 1 year if any adenoma ≥10mm or with HGD and/or villosity. ≥10 adenomas, interval is 1 year
49
First surveillance intervals following removal of serrated polyps (± conventional adenomas)
Clinically significant serrated polyps only 5 years: 1–2 sessile serrated adenomas all <10mm without dysplasia. 3 years: • 3–4 sessile serrated adenomas, all <10mm without dysplasia • 1–2 sessile serrated adenomas ≥10mm or with dysplasia, or hyperplastic polyp ≥10mm • 1–2 traditional serrated adenomas, any size. 1 year: • ≥5 sessile serrated adenomas <10mm without dysplasia • 3–4 sessile serrated adenomas, one or more ≥10mm or with dysplasia • 3–4 traditional serrated adenomas, any size With synchronous conventional adenomas 5 years for: • 2 in total, sessile serrated adenoma <10mm without dysplasia. 3 years for: • 3–9 in total, all sessile serrated adenomas <10mm without dysplasia • 2–4 in total, any serrated polyp ≥10mm and/or dysplasia • 2–4 in total, any traditional serrated adenoma. 1 year for: • ≥10 in total, all sessile serrated adenomas <10mm without dysplasia • ≥5 in total, any serrated polyp ≥10mm and/or dysplasia • ≥5 in total, any traditional serrated adenoma. Synchronous high-risk conventional adenoma (tubulovillous or villous adenoma, with or without HGD and with or without size ≥10mm) 3 years for: • 2 in total, sessile serrated adenoma <10mm, without dysplasia • 2 in total, serrated polyp ≥10mm and/or dysplasia • 2 in total, any traditional serrated adenoma. 1 year for: • ≥3 total adenomas, sessile serrated adenoma any size with or without dysplasia • ≥3 total adenomas, one or more traditional serrated adenoma.
50
First surveillance interval following removal of large sessile or laterally spreading adenomas
interval should be 12 months after en-bloc excision of large sessile and laterally spreading lesions. interval should be 6 months after piecemeal excision of large sessile and laterally spreading lesions.
51
When to stop surveillance colonoscopy
> 75 years with charleson score of >4 > 80 years
52
Small bowel obstruction investigations
Blood tests: FBC, EUC, LFTs, lipase, BSL, an ECG and a CXR. Beta-HCG in women of childbearing age, VBG for lactate. Plain films: Initial imaging should include upright CXR and erect/supine AXR films (or lateral decubitus) CT abdomen: provides more information than plain films. May be useful to identify the specific site (i.e. transition point) and severity of the obstruction (partial vs complete). It will also give information about the aetiology, by identifying hernias, masses or inflammatory changes, and potential complications, such as ischaemia or perforation.
53
Findings that suggest small bowel obstruction include:
-Dilated loops of small bowel proximal to the obstruction > 3 cm -Predominantly central dilated loops -Three instances of dilatation > 2.5 - 3 cm -Valvulae conniventes are visible -Gas-fluid levels if the study is erect, especially suspicious if >2.5 cm in width and in same loop of bowel but at different heights (> 2 cm difference in height). High-grade mechanical obstruction may also present with the following features: -Gasless abdomen -String-of-beads sign: small pockets of gas within a fluid-filled small bowel
54
Gonorrhea high risk population
1. men who have sex with men 2. young (heterosexual) Aboriginal and Torres Strait Islander people living in remote and very remote areas 3. travellers returning from high prevalence areas overseas
55
Gonoccocal treatment
Uncomplicated genital and anorectal infection - Ceftriaxone 500 mg IMI, stat. in 2 mL 1% lignocaine PLUS Azithromycin 1 g PO, stat Uncomplicated pharyngeal infection - Ceftriaxone 500 mg IMI, stat. in 2 mL 1% lignocaine PLUS Azithromycin 2 g PO, stat Adult gonococcal conjunctivitis - Ceftriaxone 1 g IMI, stat. in 2 mL 1% lignocaine PLUS Azithromycin 1 g PO, stat Treatment advice 1. Reduced susceptibility to ceftriaxone and azithromycin is emerging in urban Australia 2. Pharyngeal mucosa makes it the most likely site of treatment failure 3. If a patient has an intrauterine device (IUD), leave it in place and treat as recommended 4. Advise no sexual contact for 7 days after treatment is commenced, or until the course is completed and symptoms resolved, whichever is later. 5. Advise no sex with partners from the last 2 months until the partners have been tested and/or treated 6. Recommend partner notification 7. Provide patient with factsheet. 8. Notify the state or territory health department. 9. Consider testing for other STI 10. Consider human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP)
56
Turner Syndrome
Females - hearing, vision and fertility Treatment with hormones can help Cause - all or part of one of X chromosomes is missing
57
Warfarin guidelines
Therapeutic level: INR 2-3 <4.5, bleeding absent (lower or omit next dose, test in 2 days) 4.5-10, bleeding absent (stop doses, test in 1 day, restart at reduced dose), (optional: observation, vit k) >10, bleeding absent (stop doses, give vit K, test at 12 hrs) with minor bleeding (<10 vit k, >10 refer) with major bleeding (stop doses, vit k, prothrombinex, FFP, continuous test until <5)
58
Post stroke depression medication
fluoxetine - SSRI, 1st for PSD, CI bleeder citalopram - SSRI, 2nd for PSD, selective but weaker sertraline - SSRI, 2nd for PSD amitriptyline - TCA, but Disturbing anticholinergic SE
59
Alzheimer disease medications
CHOLINESTERASE INHIBITORS - cardiac relaxant (rest and digest functions) Donepezil Rivastigmine Galantamine NMDA RECEPTOR ANTAGONIST - neuroprotective Memantine
60
Insomnia treatment
CBT > 3 months insomnia BY CHOICE sleep onset difficulties - temazepam, zolpidem, zopiclone waking after a few hours - nitrazepam, oxazepam circadian disruption secondary to shift work or genetic predisposition - melatonin DRUG CLASS Benzodiazepines (long half life)- temazepam, nitrazepam, oxazepam and flunitrazepam - effective in reducing sleep onset latency and increasing sleep duration, exert an anxiolytic effect Non-benzodiazepines (short half life) - zolpidem and zopiclone Dual orexin receptor antagonists - Suvorexant 2ND LINE Antidepressants - insomnia patients with comorbid depression - amitriptyline, doxepin, nortriptyline, mirtazapine and agomelatine
61
Bipolar disorder treatment
ACUTE 1st trimester: Antipsychotic - risperidone, olanzapine and haloperidol Lithium 2nd and 3rd trimester: Mood stabilizer - lithium, valproate Breast feeding (no psychosis) - valproate MAINTENANCE Lithium Optional antipsychotic - quetiapine and olanzapine
62
Alcohol withdrawal syndrome
1st line - diazepam Senior, Liver disease - lorazepam, oxazepam 2nd line for psychotic featured - haloperidol,droperidol
63
Atrial fibrillation treatment
Unstable - cardioversion Stable <2 days - treat underlying condition Stable >2 days - anticoag + rate control/cardiovert later anti coag - warfarin, heparin rate control - CCB (vera or diltia), BB (olol), Digoxin, Antiarryth (darone)
64
Medication for overdoses
Hypnotics - supportive Acetaminophen - NAC Salicylates - CHO, K Opioids - Naloxone Sympathomimetics - Benzo Antimuscarinic - Benzo (physostigmine) Cholinergic - Atropine, Pralidox