Qbank1 Flashcards
(64 cards)
Osteoporosis, investigation
Diagnosis -
postmenopausal/men >50yrs
+ fracture
Scoring-
DXA
Garvan fracture risk indicator
Osteoporosis, treatment
Low risk without fracture -
falls reduction
exercise
diet, no smoking, no alcohol
education and support
The rest:
Bisphosphonates
Denosumab (rank ligand inhibitors)
Oestrogen replacement
Strontium ranelate (antiosteoporotic agent)
Triad for primary adrenal crisis
Low serum sodium
Low serum glucose
High serum potaaaium
- consider diagnosis in unexplained severe dehydration or shock
Adrenal crisis, management
Investigation
Cortisol
ACTH
17 hydroxyprogesterone
Plasma renin activity
Urinary steroid and sodium
serum pH, electrolytes and glucose
Treatment
1. steroid replacement - hydrocortisone, fludrocortisone
(glucocorticoid if mild or moderate)
2. IV fluids
3. Dextrose
4. Electrolyte adjustments
5. Treat trigger
SINBAD clasification system
- All other characteristics are scored 0
- > 3 severe ulceration
Score of 1 each
SITE - Midfoot and hindfoot
ISCHAEMIA - Clinically reduced pedal blood flow
NEUROPATHY - Sensation lost
BACTERIAL INFECTION - Present
AREA - > 1cm
DEPTH - Reaching muscle / tendon or deeper
Diabetic foot ulcer antibiotics
NONE
- just debridement and dressing
MILD
- Flucloxacillin,
- Mod Pen allergy(Cefalexin)
- Severe Pen allergy (Clindamycin)
MODERATE
- Flucloxacillin + Metronidazole
- Mod pen allergy (Cefazolin/Cefalexin + Metronidazole)
- Severe pen allergy (Clindamycin)
SEVERE
- Amoxicillin Clavulanic Acid / Piptaz
- Mod pen allergy (Cefepime + Metronidazole)
- Severe pen allergy (Clindamycin + Ciprofloxacin)
Pheochromocytoma triad
Episodic headache, sweating, and tachycardia.
Thyroxine dose adjustments
Halflife of 7-10 days
Initial doses increased every 3-4 weeks
Full benefit 3-4 months
Monitoring every 4-6 weeks until near euthyroid
Nipple discharge differentials
MILKY - medications, hyperprolactinemia (adenoma, etc)
MULTICOLORED - duct ectasia, comedomastitis
PURULENT - mastitis, abscess
WATERY SEROUS/BLOODY - intraductal papilloma, malignancy, premalignant lesion
Nipple discharge differentials
MILKY - medications, hyperprolactinemia (adenoma, etc)
MULTICOLORED - duct ectasia, comedomastitis
PURULENT - mastitis, abscess
WATERY SEROUS/BLOODY - intraductal papilloma, malignancy, premalignant lesion
Renal artery stenosis, referral criteria
Category 1 (<30 days)
Confirmed RAS + worsening renal function/hypertension
Category 2 (<90 days)
Incidental RAS of >60%
Category 3 (<365 days)
None
Requirements
History
UE
Renal USS
Acute coronary syndrome, initial management
IF OUTPATIENT:
1. Refer via ambulance for assessment
2. Aspirin
3. Sublingual GTN
IF A AND E:
1. ECG (q15 mins)
2. Biomarkers (cardiac troponin)
3. obtain Chest x-ray (old/new record)
4. Morphine if with ongoing chest pain
5. Oxygen if <93% or <88%
6. GTN if with ongoing chest pain
7. Aspirin
- If ECG is negative then repeat assessment for other life threatening causes
Acute coronary syndrome, high risk features of chest pain
Refer if with any of the following:
1. ongoing/repetitive chest pain after treatment
2. elevated troponin
3. persistent ST depression/T wave inversion
4. ST elevation (>2 leads)
5. Haemodynamic compromise
6. sustained ventricular tachycardia
7. syncope
8. known LV Ejection fraction (<40%)
9. prior ACS
Acute coronary syndrome, treatment
- GOLD STANDARD
PCI - < 12 hrs from onset, PCI not available
FIBRINOLYTICS (tenecteplase, alteplase, streptokinase)
+
ANTITHROMBIN (enoxaparin, heparin)
+
ANTIPLATELET (clopidogrel)
THEN
Coronary Angiography - Failed fibrinolysis
PCI - > 12 hrs from onset but still with chest pain
PCI
Hypertension, measurement methods
INITIAL/CVD RISK CALCULATORS
Clinic blood pressure >140/90
CONFIRMATORY
Ambulatory blood presure
Home monitioring
Hypertension, treatment targets
TREATMENT INITIATED AT:
Low absolute CVD risk >160/90mmHg
Moderate absolute CVD risk
>140/90mmHg
TREATMENT GOALS:
Uncomplicated hypertension
<140/90mmHg
CKD
<140/90mmHg
High cardiovascular risk
<120/90mmHg
Hypertension, initial medications
Uncomplicated:
1. ACEI - captopril, enalapril, etc
2. ARB - losartan, candesartan, etc
3. Calcium channel blockers - veralpamil, diltiazem, nifedipine, etc
4. Thiazide diuretics - hydrochlorothiazide, indapamide
- ACEI + ARB = Increased side effects
Specific conditions
1. CKD + Albuminuria - ACEI, ARB
2. MI - ACEI, Beta blocker
3. Symtomatic Angina - BB, CCB
4. CHF - ACEI, BB
5. Intolerant to ACEI - ARB
Rate control drugs
Amiodarone
Dronedarone
Rhythm control drugs
BB
CCB
Digoxin
Heart failure, basic investigation
ECG
Chest x-ray
Transthoracic echocardiogram
Acute heart failure, management
Oxygen - <94% O2 sat
Ventilation - persistent shortness of breath
Loop diuretics - acute heart failure
Vasodilators - >90mmHg SBP
Inotropes - Hypoperfusion
Chronic heart failure, management
ACEI: LV EF <49%
Beta Blocker: LV EF <49%
- bisoprolol, carvedilol, metoprolol, nebivolol
Mineralocorticoid receptor antagonist: LV EF <49%
Diuretics: congestion
Cardiac resynchronisation therapy
Implantable cardioverter defibrillators
Pressure monitoring
Surgery
2nd option after ACEI: ARB, ARNI, Ivabradine, Hydralazine, Digoxin, Nutraceuticals
Pericarditis, presentation
Most common symptom: sharp, piercing chest pain in the centre or left side of the chest.
Others:
low fever
heart palpitations
shortness of breath
weakness or fatigue
nausea
dry cough
swelling of the legs or abdomen
Pericarditis, management
INVESTIGATION:
ECG
Chest x-ray
Optional: Echocardiogram, CT scan, MRI
MEDICATION:
NSAID
Colchicine
Pain -relief
Optional: Anitibiotics (causes are usual idiopathic)