QC I & II Flashcards
1
Q
Aa for Digoxin
A
Pigeon
2
Q
Aa for Insulin
A
Rabbit 🐰
3
Q
Aa for Tubocurarine
A
Rabbit 🐇
4
Q
Aa for Chorionic Gonadotropin
A
Female rat🐁
5
Q
Aa for Vasopressin
A
Male rat 🐀
6
Q
Aa for Oxytocin
A
Chicken 🐔
7
Q
Aa for Glucagon
A
Cat 😺
8
Q
Aa for Corticotropin injection
A
Rat 🐁
9
Q
Aa for Cod liver oil
A
Rat 🐀
10
Q
Aa for Parathyroid hormone
A
Dog 🐶
11
Q
Aa for Heparin
A
Sheep 🐑
12
Q
Aa for Protamine
A
Sheep 🐑
13
Q
Turbidity/transmittance in microorganism 🦠🧫
A
580nm
14
Q
Turbidity/transmittance in antibiotic 💊
A
530nm
15
Q
Based on diameter of the ZOI.
Cylinder Plate/Plate Assay
Turbidimetric Method/Tube Assay
A
Cylinder Plate/Plate Assay
16
Q
based on measurement of turbidity/transmittance
Cylinder Plate/Plate Assay
Turbidimetric Method/Tube Assay
A
Turbidimetric Method/Tube Assay
17
Q
Pen G
A
S. aureus
18
Q
Bacitracin
A
Micrococcus luteus
19
Q
Streptomycin
A
Klebsiella pneumoniae
20
Q
Chloramphenicol
A
E. coli
21
Q
Vancomycin
A
B. subtilus
22
Q
Niacin, Pantothenate
A
Lactobacillus plantarum
23
Q
Cyanocobalamin
A
Lactobacillus leichmannii
24
Q
Heavy metals
A
Formation of sulfides
25
Heavy metals
Formation of sulfides
26
H2S in TS
Black
27
ZnS
White
28
CdS
Yellow
29
MnS
Pink
30
SbS
Orange
31
Arsenic
Ag diethyl dithiocarbonate (red color)
32
Chloride
AgNO3 (White ppt of AgCl)
33
Sulfates
BaCl2 (white ppt of BaS04)
34
Iron
NH4SCn(blood red of Fe)
35
Test for leaching property of crushed glass. Sulfuric Acid is used
Powder Glass Test
Water Attack Test
Surface Glass Test
Light Transmission Test
Arsenic Release Test
For what type of glass?
Powder Glass Test
Type l & ll
36
Test for leaching property of intact surface of containers. Sulfuric Acid is used
Powder Glass Test
Water Attack Test
Surface Glass Test
Light Transmission Test
Arsenic Release Test
For what type of glass?
Water Attack Test
Type lI Glass only
37
Determines hydrolytic resistance of inner surface of glass. HCI VS is used
Powder Glass Test
Water Attack Test
Surface Glass Test
Light Transmission Test
Arsenic Release Test
For what type of glass?
Surface Glass Test
Type I, Il, Ill
38
Initial Moisture Content limit?
0.5-1%
10-20%
25-30%
31-35%
31-35%
39
Adequacy of wetness limit?
0.5-1%
10-20%
25-30%
31-35%
0.5-1%
40
Dry sieving (for particles > 75 micrometer in diameter)
Airjet
Sonic sifting
Mechanical Sieving/Agitation
Mechanical Sieving/Agitation
41
for < 75 micrometer, single sieve at a time
Airjet
Sonic sifting
Mechanical Sieving/Agitation
Airjet
42
for <75 micrometer, nest of sieves
Airjet
Sonic sifting
Mechanical Sieving/Agitation
Sonic sifting
43
force required to break Compressed uncoated tab
4-10 kg
7-10 kg
2-3 kg
>10 kg
4-10 kg
44
force required to break Chewable Tablet
4-10 kg
7-10 kg
2-3 kg
>10 kg
2-3 kg
45
force required to break Buccal Tablet
4-10 kg
7-10 kg
2-3 kg
>10 kg
7-10 kg
46
force required to break MR tablets
4-10 kg
7-10 kg
2-3 kg
>10 kg
>10 kg
47
Immediate release
30 mins H2O
48
Buccal Tabs
4hrs H2O
49
Sublingual Tabs
2-3mins H2O
50
Enteric Coated Tabs
5 mins H2O
1 hr simulated gastric/intestinal fluid
51
Apparatus I
Basket
52
Apparatus ll
Paddle
53
Apparatus lll
Reciprocating Cylinder
54
Apparatus lV
Flow through Cell
55
Apparatus V
Paddle over Disk
56
Apparatus Vl
Revolving Cylinder
57
Apparatus Vll
Reciprocating Holder
58
test for ampoules; Dye: 1% Methylene Blue
Leaker's Test
59
examination for the presence of particulate matters
Clarity Test
60
ensures that the sterilization process done was successful.
Freedom from the presence of viable microorganism.
Sterility Test
61
anaerobic bacteria (Clostridium), Preudomonas, S. areus (Aerobic bac)
Fluid Thioglycollate Medium
62
aerobic bacteria & fungi, Bacillus subtlis, Candida albicans
Soybean Casein Digest Medium
63
qualitative biological test based on fever response of rabbits (inj. In ear vein), 10ml of sample/kg by injection.
Pyrogen Test
64
measures the concentration of bacterial endotoxin that may be present in the sample using a lysate derived from the amoebocytes of the horsehoe crab, Limulus polyphemus.
Bacterial Endotoxin Test (BET/LAL Test)
65
refers to the extraneous, mobile undissolved particles, other than gas bubbles, unintentionally present in the solutions.
Particulate Test
66
21 C/45% RH
Temperate
67
30C/35% RH
(Middle East)
Hot and Dry
68
25C/60% RH
Mediterranean/Subtropical
69
30C/65-75% RH
(Philippines)
Hot and Humid
70
Testing: Extreme Conditions Storage
Min. Time Period: 6 months (0,3,6)
Accelerated Studies
71
Testing points: 0,3,6,9,12,18, 24, 36
Minimum Time Period: 12 months or 1 year
Normal or Long Term/ Real Time Studies
72
<1.0mg
Ultramicroanalysis
73
1.0-10.0mg
Microanalysis
74
10.0-100.0mg
Semimicro/meso
75
100mg- 1000mg or 1g
Macroanalysis
76
closeness of an actual value to the theoretical value.
Accuracy
77
closeness of two or more actual values.
Precision
78
Error due to uncontrollable variable. Affects precision
Random (Indeterminate) Error
79
Error that has definite & identifiable cause. Affects accuracy
Systematic (Determinate) Error
80
Error that occurs occasionally
Gross Error
81
proton is transformed from one molecule to another.
Protolysis
82
proton is transformed from one molecule to another identical molecule.
Autoprotolysis
83
ability of a substance to act as either an acid or base.
Amphoteric
84
Determination of volume of a solution of known concentration required to react with a given amount of substance to be analyzed.
Titration/Titrimetry/Volumetric
85
separation by extraction, precipitation or other means of the constituent to be determined either in the natural state or in a form of a definite compound, the composition of which is known to the analyst ,and the weighing of the resulting product.
Used in the test for natural products or crude drugs
Gravimetric Analysis
86
techniques which require a distinct type of technique based on the properties and nature of the material being assayed.
Special Methods/Miscellaneous Methods
87
method in which the volume of a solution of known concentration consumed during analysis is taken as a measure of the amount of active constituent in a sample being analyzed.
Titrimetric Method
88
reagent of known concentration
Titrant/Vol. solution/ Standard Solution
89
sample being analyze (ERLENMEYER FLASK)
Titrand/Analyte/Active Constituent
90
a process of adding and measuring the volume of titrant used in the assay by means of a burette.
Titration
91
amount of substance (mg), chemically equivalent to 1 ml of standard solution.
Titer Value
92
process of repeating the entire procedure but omitting the analyte/sample.
Blank determination
