QTC prolongation

Question 1

Name the modifiable risk factors for QTc prolongation?

Answer 1

Bradycardia, electrolyte disturbances and concomitant use of 2+ drugs that cause QTc prolongation

Question 2

Name the non-modifiable risk factors for QTc prolongation?

Answer 2

Congenital QT prolongation, >65 years old, female sex, thyroid impairment, hepatic and renal impairment, cardiac disease

Question 3

Name the antimicrobials that cause QT prolongation?

Answer 3

Macrolides, quinolones, and azoles

Question 4

Name the antidepressants that cause QT-prlongation?

Answer 4

Citalopram, Amitriptyline, Clomipramine, Dosulepin, Imipramine, Fluoxetine, Sertraline, Venlafaxine

Question 5

Name the antiemetics that cause QT prolongation?

Answer 5

Domperidone, Ondansetron

Question 6

Name the anti-arrythmetics that cause QT prolongation?

Answer 6

Dronedarone, Fleicanide, Amiodarone, Sotalol, Quinidine

Question 7

Name the anti-arrythmetics that cause QT prolongation?

Answer 7

All antipsychotics have some risk but mainly: risperidone, quetiapine, clozapine, haloperidol, chlorpromazine

Question 8

Others that cause QT prolongation?

Answer 8

Methadone, Quinines, Sumatriptan