Quan Study Guide Flashcards

(40 cards)

1
Q

glycolysis starts from ____ and ends at ____

A

glucose; lactate

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2
Q

glucose can be used to generate ____, ____, ____, ____, and _____

A

ATP; glycogen; ribose; lipid molecules; NADPH

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3
Q

glycolysis has an ____ and ____ stage

A

investment; yield

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4
Q

____ can be trapped in a cell in the form of ____

A

glucose; Glc-6-P

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5
Q

the rate limiting enzyme of glycolysis is ____

A

PFK-1

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6
Q

____ and ____ catalyze the yield of ____ in glycolysis

A

PGK; pyruvate kinase; ATP

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7
Q

Glycolysis uses ____ to generate ____; the net gain is ____

A

2 ATP; 4 ATP; 2 ATP

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8
Q

Pyruvate can be transformed to ____ in order to regenerate ____

A

lactate; NAD+

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9
Q

hexokinase can be inhibited by _____

A

Glc-6-P

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10
Q

PFK-1 can be inhibited by ____, activated by ____

A

ATP; AMP

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11
Q

pyruvate kinase can be activated by ____

A

fructose-1,6-BP

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12
Q

_____ pathway is important for the generation of ____ and _____

A

pentose phosphate; NADPH; ribose

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13
Q

formula of glycogen

A

C24 H42 O21

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14
Q

_____ is used for the building block for glycogen

A

UDP-glucose

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15
Q

_____ extends the chain of glycogen

A

glycogen synthase

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16
Q

_____ initiates glycogen synthesis

A

glycogenin

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17
Q

_____ catalyzes the breakdown of glycogen

A

glycogen phosphorylase

18
Q

inhibition of _____ can be used to treat diabetes

A

glycogen phosphorylase

19
Q

____ is an enzyme that stimulates _____

A

glucagon; glycogenolysis

20
Q

____ and _____ act to increase the activity of glycogen phosphorylase

A

epinephrine; glucagon

21
Q

_____ is almost the reverse of glycolysis

A

gluconeogenesis

22
Q

where does the TCA cycle occur?

A

in eukaryotic cells, the TCA cycle occurs in the mitochondria matrix

23
Q

two major functions of the TCA cycle

A
  1. increase cell’s ATP-producing potential by generating reduced electron carriers NADH and ubiquinone
  2. provide cell with a variety of metabolic precursors
24
Q

____ is the starting point of the TCA cycle- can be formed from many different molecules like ___, ____, ____ etc.

A

acetyl-CoA; sugars; fats; amino acids

25
____ and ____ is used for oxidative phosphorylation
NADH; FADH2
26
TCA gives ____ for citric acid cycle- which gives ____ that is converted to _____
citrate; malate; carbohydrate
27
4 dehydrogenases in the TCA cycle
- isocitrate dehydrogenase - alpha-ketoglutarate dehydrogenase - succinate dehydrogenase - malate dehydrogenase
28
____ and _____ can both be derived from pyruvate
acetyl-CoA; oxaloacetate
29
_____ catalyzes the synthesis of acetyl-CoA
pyruvate dehydrogenase
30
the 4 oxidative enzymes in the TCA cycle are:
- isocitrate dehydrogenase (isocitrate DH) - alpha-ketoglutarate dehydrogenase (AKG DH) - succinate dehydrogenase - malate dehydrogenase
31
pyruvate dehydrogenase is negatively regulated by:
- ATP - Acetyl-CoA - NADH
32
acceptor molecule in the TCA cycle
oxaloacetic acid (OAA)
33
outputs from the cycle (besides CO2) which are energy metabolites:
- 3 NADHs - 1 FADH2 - GTP
34
isocitrate DH is also a ____ and has ____ as a cofactor
decarboxylase; manganese
35
overall isocitrate rxn producing ____, ____, and _____ (a 5 carbon dicarboxylic acid), and it is nicely ____
CO2; NADH; alpha-keto-glutarate; exothermic
36
____ is called "old yellow"
succinate dehydrogenase
37
fumarase forms ____
malate
38
malate dehydrogenase is _____
endothermic
39
NADH is worth ____ ATP and FADH2 is worth ___ ATP
2.5; 1.5
40
one molecule of glucose produces ____ ATPs
30-32