Question Bank 3 - HPA axis

Question 1

When does peak cortisol response typically occur?

Answer 1

20 min after start of stressor.

Question 2

When does baseline return after initial stressor?

Answer 2

~ 1 hour

Question 3

Norephinephrine and epinephrine are derived from ____.

Answer 3

Tyrosine

Question 4

Neuroendocrine cells of the hypothalamus secrete ____________ hormones into the _________________.

Answer 4

Releasing hormones, hypothalamic-pituitary portal system

Question 5

What are the major releasing hormones for ACTH?

Answer 5

CRF/CRH (corticotropin releasing hormone) and Arginine Vasopressin

Question 6

What is the median eminence?

Answer 6

Where axons of neuroendocrine CRH containing PVN terminate.

Question 7

What types of hormones are there and give example of each?

Answer 7

1. Amine hormone: Epinephrine and norepinephrine
2. Peptide hormone: ACTH
3. Steroid hormone: Cortisol

Question 8

Which nucleus of the hypothalamus is PRIMARILY associated with driving the HPA axis response?

Answer 8

Paraventricular Nucleus: Regulates autonomic and endocrine functions