Quimioterápicos Flashcards
(18 cards)
cyclophosphamide (action)
alkylating agent
What type of agent is cisplatin?
A DNA intercalating agent
Cisplatin is used in cancer chemotherapy.
What is fluorouracil also known as?
5-FU
Fluorouracil is classified as an antimetabolite.
What class of drug is doxorubicin?
An anthracycline
Doxorubicin is commonly used in cancer treatment.
What type of inhibitor is vincristine?
A mitotic spindle inhibitor
Vincristine disrupts cell division.
What is the mechanism of action for bleomycin?
Cytotoxic agent
Bleomycin is used to treat various cancers.
What type of drug is gemcitabine?
An antimetabolite
Gemcitabine is a newer cytotoxic agent.
Oxaliplatin is an analog of which drug?
Cisplatin
Oxaliplatin is used in treating colorectal cancer.
What are paclitaxel and docetaxel classified as?
The ‘taxanes’
They are mitotic spindle poisons.
Irinotecan is a type of what inhibitor?
Topoisomerase inhibitor
Irinotecan is used in cancer chemotherapy.
What are some examples of drugs that can affect peripheral nerves?
Vinca alkaloids, cisplatin, taxanes
Peripheral nerves can be affected by various chemotherapeutic agents.
Which drugs are associated with lung toxicity?
Bleomycin, gemcitabine
These drugs can lead to lung damage or pulmonary toxicity.
What organ can be affected by cisplatin?
Kidneys
Cisplatin is known for its nephrotoxic effects.
Which class of drugs can affect the heart?
Anthracyclines
Anthracyclines are linked to cardiotoxicity.
Name a drug that can impact the central nervous system.
High-dose methotrexate, 5-FU
These drugs can have neurotoxic effects at elevated doses.
True or False: Nearly any organ can be affected by drugs depending on the specific drug.
True
The effects of drugs can vary widely based on their chemical properties.
What do monoclonal antibodies target?
Cell surface antigens
Monoclonal antibodies are designed to bind specifically to certain antigens on the surface of cells.
What do kinase inhibitors target?
Various signaling molecules
Kinase inhibitors interfere with the action of kinases, which are enzymes that modify other proteins by adding phosphate groups.
