Quiz 1 Flashcards

(472 cards)

1
Q

Hazardous material

A

substances that cause adverse health effects upon human exposure.

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2
Q

Index of suspicion

A

anticipation of possible injuries based on analysis of the event.

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3
Q

Mechanism of injury

A

combined strength, direction, and nature of forces that injured the patient.

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4
Q

Personal Protective Equipment (PPE)

A

equipment designed to protect against infection. The minimum recommended PPE includes protective gloves, masks and protective eyewear, HEPA and N-95 respirators, gowns, and disposable resuscitation equipment.

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5
Q

Scene safety

A

doing everything possible to ensure a safe environment.

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6
Q

Standard Precautions

A

a strict form of infection control based on the assumption that all blood and other body fluids are infectious.

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7
Q

Circulation Assessment

A

evaluation of the pulse and skin and control of hemorrhage.

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8
Q

Decerebrate

A

arms and legs extended.

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9
Q

Decorticate

A

arms flexed, legs extended.

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10
Q

General impression

A

the initial, intuitive evaluation of the patient.

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11
Q

Primary assessment

A

prehospital process designed to identify and correct life-threatening airway, breathing, and circulation problems.

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12
Q

Closed questions

A

questions that ask for specific information and require only very short or yes-or-no answers; also called direct questions.

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13
Q

Closed stance

A

a posture or body position that is tense and suggests negativity, discomfort, fear, disgust, or anger.

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14
Q

Communication

A

the exchange of common symbols–written, spoken, or other kinds, such as signing and body language.

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15
Q

Cultural imposition

A

the imposition of one’s beliefs, values, and patterns of behavior on people of another culture.

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16
Q

Decode

A

interpret a message.

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17
Q

Delirium

A

an acute alteration in mental functioning that is often reversible.

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18
Q

Dementia

A

a deterioration of mental status that is usually associated with structural neurologic disease.

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19
Q

Depression

A

a mood disorder characterized by hopelessness and malaise.

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20
Q

Empathy

A

identification with and understanding of another’s situation, feelings, and motives.

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21
Q

Encode

A

create a message.

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22
Q

Ethnocentrism

A

viewing one’s own way of life as the most desirable, acceptable, or best, and acting in a superior manner to another culture’s way of life.

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23
Q

Feedback

A

a response to a message.

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24
Q

Leading questions

A

questions framed to guide the direction of a patient’s answers.

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25
Nonverbal questions
gestures, mannerisms, and postures by which a person communicates with others; sometimes called body language.
26
Open stance
a posture or body position that is relaxed and suggests confidence, ease, warmth, and attentiveness.
27
Open ended questions
questions that permit unguided, spontaneous answers.
28
Chief Complaint
the pain, discomfort, or dysfunction that caused the patient to request help.
29
Differential field diagnosis
the list of possible causes for the patient’s symptoms.
30
Diuretic
a medication that stimulates the kidneys to excrete water.
31
Dysmenorrhea
difficult or painful menstruation.
32
Dyspnea
the sensation of having difficulty breathing.
33
HEENT
head, eyes, ears, nose, and throat.
34
Hematemisis
vomiting of blood.
35
Hematuria
blood in the urine.
36
Hemoptysis
coughing up of blood.
37
Intermittent claudication
intermittent calf pain while walking that subsides with rest.
38
Nocturia
excessive urination at night.
39
Orthopnea
difficulty breathing while lying supine.
40
Paroxysmal nocturnal dyspnea
sudden onset of shortness of breath at night.
41
Polyuria
excessive urination.
42
Primary problem
the underlying cause for the patient’s symptoms.
43
Referred pain
pain that is felt in a location away from its source.
44
Tenderness
pain that is elicited through palpation.
45
Tinnitus
the sensation of ringing in the ears.
46
Afterload
resistance in the blood vessels that the heart must overcome to eject blood.
47
Aphasia
defective language caused by neurologic damage to the brain.
48
Ascites
bulges in the flanks and across the abdomen, indicating edema caused by congestive heart failure.
49
Auscultation
listening with a stethoscope for sounds produced by the body.
50
Babinski's response
big toe dorsiflexes and the other toes fan out when the sole is stimulated.
51
Blood pressure
force of blood against arteries’ walls as the heart contracts and relaxes.
52
Borborgymi
loud, prolonged, gurgling bowel sounds indicating hyperperistalsis.
53
Bradycardia
pulse rate lower than 60.
54
Bronchophony
abnormal clarity of the patient’s transmitted voice sounds.
55
Broselow tape
a measuring tape for infants that provides important information regarding airway equipment and medication doses based on the patient’s length.
56
Bruit
sound of turbulent blood flow around a partial obstruction.
57
Cardiac output
the amount of blood the heart ejects each minute, measured in milliliters.
58
Crackles
light crackling, popping, nonmusical sounds heard usually during inspiration; also called rales.
59
Crepitus
crunching sounds of unlubricated parts in joints rubbing against each other.
60
Cullen's sign
discoloration around the umbilicus (occasionally the flanks) suggestive of intraabdominal hemorrhage.
61
Diastole
phase of cardiac cycle when ventricles relax.
62
Diastolic blood pressure
force of blood against arteries when ventricles relax.
63
Dysarthria
defective speech caused by motor deficits.
64
Dysphonia
voice changes caused by vocal cord problems.
65
Edema
presence of an abnormal amount of fluid in the tissues.
66
Egophony
abnormal change in tone of the patient’s transmitted voice sounds.
67
Grey Turner's sign
discoloration over the flanks suggesting intraabdominal bleeding.
68
Hypertension
blood pressure higher than normal.
69
Hyperthermia
increase in the body’s core temperature.
70
Hypotension
blood pressure lower than normal.
71
Hypothermia
decrease in the body’s core temperature.
72
Inspection
the process of informed observation.
73
Korotkoff sounds
sounds of blood hitting arterial walls.
74
Ophthalmoscope
handheld device used to examine the interior of the eye.
75
Otoscope
handheld device used to examine the interior of the ears and nose.
76
Palpation
using one’s sense of touch to gather information.
77
Percussion
the production of sound waves by striking one object against another.
78
Perfusion
passage of blood through an organ or tissue.
79
Pleural friction rub
the squeaking or grating sound of the pleural linings rubbing together.
80
Preload
amount of blood returned to the heart from the body; also known as end-diastolic pressure.
81
Priapism
a painful and prolonged erection of the penis.
82
Pulse pressure
difference between systolic and diastolic pressures.
83
Pulse quality
strength of the pulse, which can be weak, thready, strong, or bounding.
84
Pulse rate
number of pulses felt in 1 minute.
85
Pulse rhythm
pattern and equality of intervals between beats.
86
Quality of respiration
depth and pattern of breathing.
87
Respiration
exchange of oxygen and carbon dioxide in the lungs and at the cellular level.
88
Respiratory effort
how hard the patient works to breathe.
89
Respiratory rate
number of times the patient breathes in 1 minute.
90
Rhonchi
continuous sounds with a lower pitch and a snoring quality.
91
Sphygmomanometer
blood pressure measuring device comprising a bulb, a cuff, and a manometer.
92
Stethoscope
tool used to auscultate most sounds.
93
Stridor
predominantly inspiratory wheeze associated with laryngeal obstruction.
94
Stroke volume
the amount of blood the heart ejects in one beat.
95
Systole
phase of cardiac cycle when ventricles contract.
96
Systolic blood pressure
force of blood against arteries when ventricles contract.
97
Tachycardia
pulse rate higher than 100.
98
Tachypnea
rapid breathing.
99
Thrill
vibration or humming felt when palpating the pulse.
100
Tidal volume
amount of air one breath moves in and out of the lungs.
101
Visual acuity wall chart/card
wall chart or handheld card with lines of letters, used to test vision.
102
Vital statistics
weight and height.
103
Wheezes
continuous, high-pitched musical sounds similar to a whistle.
104
Whispered pectoriloquy
abnormal clarity of the patient’s transmitted whispers.
105
Abdomino-
Belly or abdominal wall
106
Acou-
To hear
107
Acq-
Water
108
Acro-
Extreme ends of parts
109
Aden-
A gland
110
Adip-
Soft fat of animals
111
Alb-
White
112
Alg-
Pain
113
All-
Other, different
114
Anc-, ang-, ank-
Bend or hollow
115
Andr-
Male
116
Angi-
Blood vessel
117
Aort-
Large artery exiting from left ventricle
118
Arter-
Artery
119
Arth-
Joint
120
Artic
Joint
121
Asphyxia
Unconsciousness due to suffocation
122
Astha-
Short drawn breath, panting
123
Asthenia
Weakness
124
Aud-, aur-, aus-
To hear
125
Bio-
Life
126
Brachy-
Short
127
Branchi-
Arm
128
Bronch-
One of the major divisions of the trachea
129
Bucc-
Cheek
130
Burs-
Pouch or sac
131
Caes-, cis
Cut
132
Call-
Hard, thick skin
133
Calx, calca-
Heel
134
Can-
Malignant tumor
135
Caput, capitis
Head
136
Carc-
Cancer
137
Card-, cardia
Heart
138
Carotid
Great arteries of the neck
139
Carpus
Wrist
140
Caus-, caut-
To burn
141
Celi-
Hollow or cavity, specifically the abdomen
142
Cent-
Center, centimeter, centigrade
143
-centesis
Puncture of a cavity
144
Ceph-
Head
145
Cerv-
Neck
146
Chol-
Bile
147
Chond-
Cartilage
148
Chrom-
Color
149
Cil-
Hairlike process
150
Cleid-
Collarbone (clavicle)
151
Cochlea
Part of the inner ear
152
Coll-
Gelatin, neck
153
Cond-
Knuckle
154
Core
Pupil
155
Cori-
Skin
156
Corp-
The body
157
Cry-
Cold
158
Cubitus
Elbow
159
-cuss
Shake violently
160
Cyan-
Blue
161
Cyc-
Circle
162
Cyst
Bladder, cyst
163
Dent-
Tooth
164
Derm-
Skin
165
Digit
Finger
166
Duct
To lead or guide
167
Edem-
Swelling
168
Embryo
Fetus
169
Enter-
Intestines
170
Eryth-
Red
171
-esth
Sensation
172
Eti-
Cause
173
Facil-
Easy
174
Febr-
Fever
175
Flex
To bend
176
Foramen
Opening
177
Fract-
To break into pieces
178
Gangl-
Tumor under the skin, junction of the nerve cells
179
Gangr-
Gnawing sore
180
Gast-
Stomach, belly
181
Gen-, gon-
Become, produce
182
Gest-
Carry, produce
183
Glomerulus
Plexus of capillaries
184
Gnosis
Knowledge
185
-gram
Something written
186
-graph
To write
187
Gyn-
Female
188
Hem-, em
Blood
189
Hepat-
Liver
190
Heter-
Other, different
191
Homo-
The same
192
Humerus
Upper arm
193
Hydr-
Water
194
Hyster-
The womb
195
Idi
Personal, one's own
196
Idio-
Distinct
197
Ingui-
Front of body, between hips and groin
198
Lact-
Milk
199
Lev-
Left side
200
Ligament
Band of fibrous tissue connecting two bones
201
Ling-
Tongue
202
-lith-
Stone
203
Mal-
Bad
204
Meatus
External opening
205
Med-
Middle
206
Mega-
Large
207
Melan-, melen-
Black
208
Men-, mena-
Monthly
209
Menin-
Membrane covering brain and spinal cord
210
Morb-
Disease
211
Myel-
Marrow or spinal cord
212
Myo-
Muscle
213
Nephr-
Kidney
214
Noct-
Night
215
Nomen-, nomin-
Name
216
Oa-, oss-, ost-
Bone
217
Ocul-
Eye
218
Odon-
Tooth
219
Oo-, ov-
Egg
220
Opthalm-
Eye
221
Orch-
Testis
222
Ot-
Ear
223
Palpate
To touch
224
Pari-, part-
To bear
225
Pariet-
Wall
226
Path-
Disease
227
Pea-, ped-
Foot
228
Ped-
Child
229
Percuss
To strike
230
Phag
To eat
231
Photo-
Light
232
Placenta
Organ supplying nutrients to the fetus during gestation
233
Pleur-
Membrane surrounding lung and lining the thoracic cavity
234
Pneum-
Breathing
235
Pod-
Foot
236
Pseud-
False
237
Psych-
Mind
238
Ptosis
Falling down
239
Pty-
Spit out
240
Pur-, pus-, py-
Pus
241
Pyel-
Pelvis (including pelvis of kidney)
242
Pyr-
Fever
243
Quad-, quar-, quat-
Four
244
Radius
Rod
245
Ren-
Kidney
246
Reticulum
Network
247
Retina
Inner nerve-containing layer of the eye
248
Rhin-
Nose
249
Rub-
Red
250
Salpinx
Tube
251
Sang-
Blood
252
Scler-
Hard
253
Sebum
Hard fat of animals
254
Sect-, seg-
To cut
255
Sepsis
Containing growing bacteria
256
Sept-
Wall
257
Serum
Fluid formed when blood clots
258
Sinus
Cavity or hollow
259
Somat-
Body
260
Sphincter
Muscle that closes when it contracts
261
Spir-
Coil
262
Stasis
Standing
263
Stature
Height
264
Status
Condition
265
Stern-
Chest
266
Stoma
Opening or mouth
267
Sulc-
Groove on surface of brain
268
Tachy-
Rapid
269
Tact-
To touch
270
Talus
Heel
271
Tarsus
Bones of the forefoot
272
Tel-
Distance
273
Temp-
Time, or temple of the head
274
Tendon
Fibrous tissue connecting muscle to bone
275
Tetr-
Four
276
Tom-
To cut
277
Toxic
Poisonous
278
Trachea
Windpipe
279
Trich-
Hair
280
Ur-, urin-
Urine
281
Vagina
Female genital canal
282
Varic-
Dilated vein
283
Vertebra
Bone supporting the spinal column
284
Vertex
Top of the skull
285
Vertigo
Dizziness
286
Viscera
Internal organs
287
Viscous
Sticky
288
Xen
Foreign
289
Xer-
Dry
290
Administration tubing
flexible, clear plastic tubing that connects the solution bag to the IV cannula.
291
Air embolism
air in the vein.
292
Ampule
breakable glass vessel containing liquid medication.
293
Anticoagulant
medication that inhibits blood clotting.
294
ABO blood groups
four blood groups formed by the presence or absence of two antigens known as A and B. A person may have either (type A or type B), both (type AB), or neither (type O). An immune response will be activated whenever a person receives blood containing A or B antigen if this antigen is not already present in his own blood.
295
Acid base reactions
any chemical reaction that results in the transfer of protons.
296
Acquired immunity
protection from infection or disease that is (1) developed by the body after exposure to an antigen (active acquired immunity) or (2) transferred to the person from an outside source such as from the mother through the placenta or as a serum (passive acquired immunity).
297
Acute
of sudden onset, as an acute disease.
298
Adipocytes
fat cells.
299
Adipose tissue
fat.
300
Anaphylaxis
a life-threatening allergic reaction; also called anaphylactic shock.
301
AIDS
a group of signs, symptoms, and disorders that often develop as a consequence of HIV infection. (Acquired immunodeficiency syndrome)
302
Albumin
a protein commonly present in plant and animal tissues. In the blood, albumin works to maintain blood volume and blood pressure and provides colloid osmotic pressure, which prevents plasma loss from the capillaries.
303
Allergy
exaggerated immune response to an environmental antigen.
304
Amylopectin
a highly branched polymer of glucose; one of two types of starch, the other being amylose.
305
Amylose
a linear, unbranched polymer of glucose; one of two types of starch, the other being amylopectin.
306
Anencephaly
a birth defect in which a baby is born without parts of the brain and skull.
307
Antibiotic
agent that kills or decreases the growth of bacteria.
308
Antibody
a substance produced by B lymphocytes in response to the presence of a foreign antigen that will combine with and control or destroy the antigen, thus preventing infection.
309
Antigen
a marker on the surface of a cell that identifies it as “self” or “non-self.”
310
Antigen-antibody complexes
the substance formed when an antibody combines with an antigen to deactivate or destroy it; also called immune complex.
311
Antigen presenting cells
cells, such as macrophages, that present (express onto their surfaces) portions of the antigens they have digested.
312
Antigen processing
the recognition, ingestion, and breakdown of a foreign antigen, culminating in production of an antibody to the antigen or in a direct cytotoxic response to the antigen.
313
Apoptosis
response in which an injured cell releases enzymes that engulf and destroy itself; one way the body rids itself of damaged and dead cells.
314
Atrophy
a decrease in cell size resulting from a decreased workload.
315
Autoimmune disease
failure of the immune system to recognize certain tissues normally present in the body resulting in an attack against those tissues by the immune system; autoimmune disease includes rheumatic heart disease and rheumatoid arthritis.
316
Autoimmunity
an immune response to self-antigens, which the body normally tolerates.
317
B lymphocytes
the type of white blood cells that, in response to the presence of an antigen, produce antibodies thatattack the antigen, develop a memory for the antigen, and confer long-term immunity to the antigen.
318
Bacteria
(singular bacterium) single-cell organisms with a cell membrane and cytoplasm but no organized nucleus. They bind to the cells of a host organism to obtain food and support.
319
Basement membrane
a thin sheet of fibers that underlies the epithelia, the membranes that line or cover internal and external body surfaces.
320
Basophils
granular white blood cells that, similarly to mast cells, release histamine and other chemicals that control constriction and dilation of blood vessels during inflammation.
321
Benign
not cancerous; not able to spread to other tissues. See also malignant.
322
Carcinogenesis
a process of developing a cancer.
323
Carcinoma-in-situ
an early form of cancer in which tumor cells have not yet invaded surrounding tissues.
324
Cardiac contractile force
the strength of a contraction of the heart.
325
Cardiogenic shock
shock caused by insufficient cardiac output; the inability of the heart to pump enough blood to perfuse all parts of the body.
326
Cartilage
a type of connective tissue that provides structure and support to other tissues.
327
Cascade
a series of actions triggered by a first action and culminating in a final action—typical of the actions caused by plasma proteins involved in the complement, coagulation, and kinin systems.
328
Catecholamines
epinephrine and norepinephrine, hormones that strongly affect the nervous and cardiovascular systems, metabolic rate, temperature, and smooth muscle.
329
Cell mediated immunity
the short-term immunity to an antigen provided by T lymphocytes, which directly attack the antigen but do not produce antibodies or memory for the antigen.
330
Cellular adaption
physiologic or structural changes to a cell in response to change or stress or a pathological condition.
331
Cellular respiration
metabolic processes with a cell that convert nutrients to energy in the form of adenosine triphosphate (ATP) and that subsequently release waste products from the cell.
332
Chemotactic factors
chemicals that attract white cells to the site of inflammation, a process called chemotaxis.
333
Chromatin
a combination of DNA and other proteins in the nucleus of a cell that condenses to form chromosomes.
334
Chromosomes
threadlike structures within the nuclei of cells that carry genetic information.
335
Chronic
slow in onset, persisting over a long period of time, as in a chronic disease.
336
Cisternae
saclike structures within body cells that form part of the structure of rough endoplasmic reticulum (RER) and of the Golgi apparatus and act as carrier vessels that transport proteins from the RER to the Golgi apparatus for further processing.
337
Citric acid cycle
a key phase of glucose metabolism, requiring the presence of oxygen, in which pyruvic acid (a product of the breakdown of glucose) is oxidized, resulting in the release of energy in the form of ATP and carbon dioxide as waste. Also called Krebs cycle or the tricarboxylic acid (TCA) cycle.
338
Clinical presentation
the manifestation of a disease; the signs and symptoms of a disease.
339
Clonal diversity
the development of receptors, by B lymphocyte precursors in the bone marrow, for every possible type of antigen.
340
Chemoreceptors
sensory receptors that detect and act on chemical signals—for example, sensing a change in carbon dioxide levels in the blood and responding by causing an increase in respiratory rate to expel the excess carbon dioxide from the body.
341
Clonal selection
the process by which a specific antigen reacts with the appropriate receptors on the surface of immatureB lymphocytes, thereby activating them and prompting them to proliferate, differentiate, and produce antibodies to the activating antigen.
342
Coagulation system
a plasma protein system that results in formation of a protein called fibrin. Fibrin forms a network that walls off an infection and forms a clot that stops bleeding and serves as a foundation for repair and healing of a wound. Also called the clotting system.
343
Coenzymes
nonprotein substances that bind to enzyme proteins to assist them in biochemical transformations. Also called cofactors.
344
Collagen
proteins that are the main component of connective tissue.
345
Colloid
intravenous solutions containing large proteins that cannot pass through capillary membranes.
346
Compensated shock
early stage of shock during which the body’s compensatory mechanisms are able to maintain normal perfusion.
347
Complement system
a group of plasma proteins (the complement proteins) that are dormant in the blood until activated, as by antigen-antibody complex formation, by products released by bacteria, or by components of other plasma protein systems. When activated, the complement system is involved in most of the events of inflammatory response.
348
Complications
abnormalities or conditions that result from another, original disease or problem. Also called sequelae.
349
Congenital metabolic diseases
diseases affecting the metabolism that are present from birth.
350
Connective tissue
the most abundant body tissue; it provides support, connection, and insulation. Examples: bone, cartilage, fat, blood.
351
Contraction
inward movement of wound edges during healing that eventually brings the wound edges together.
352
Cortisol
a steroid hormone released by the adrenal cortex that regulates the metabolism of fats, carbohydrates, sodium, potassium, and proteins and also has an anti-inflammatory effect.
353
Cristae
folds within mitochondria that form shelves within the mitochondria.
354
Crystalloids
intravenous solution that contains electrolytes but lacks the larger proteins associated with a colloid.
355
Cytokines
proteins, produced by white blood cells, that regulate immune responses by binding with and affecting the function of the cells that produced them or of other, nearby cells.
356
Cytotoxic
toxic, or poisonous, to cells.
357
Debridement
the cleaning up or removal of debris, dead cells, and scabs from a wound, principally through phagocytosis.
358
Decompensated shock
advanced stages of shock when the body’s compensatory mechanisms are no longer able to maintain normal perfusion; also called progressive shock.
359
Degranulation
the emptying of granules from the interior of a mast cell into the extracellular environment.
360
Dehydration
excessive loss of body fluid.
361
Delayed hypersensitivity reaction
a hypersensitivity reaction that takes place after the elapse of some time following reexposure to an antigen. Delayed hypersensitivity reactions are usually less severe than immediate reactions.
362
Denaturation
loss of a protein’s three-dimensional shape caused by factors such as heat, chemicals, or pH; the change in the appearance and structure of an egg white when it is cooked is an example of denaturation.
363
Diagnosis
the process of identifying and assigning a name to a disease in an individual patient or a group of patients with similar signs and symptoms.
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Diapedesis
movement of white cells out of blood vessels through gaps in the vessel walls that are created when inflammatory processes cause the vessel walls to constrict.
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Disease
an abnormal structural or functional change within the body.
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Dynamic steady state
homeostasis; the tendency of the body to maintain a net constant composition although the components of the body’s internal environment are always changing.
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Dysplasia
a change in cell size, shape, or appearance caused by an external stressor.
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Dysplastic
having an abnormal appearance, as with a cell seen under a microscope.
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Ectoderm
the outermost of three germ layers, primitive cell types that develop in the embryo and that will differentiate into the various tissues and organs of the body. See alsoendoderm; germ layers; mesoderm.
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Electron transport chain
carriers embedded on the cristae in the inner membrane of the mitochondria of cells that transfer electrons from one molecule to another, releasing energy in the process.
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Endocrine secretions
secreted substances that are released into the bloodstream or surrounding tissues without the aid of ducts.
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Endocytosis
process by which substances can enter a cell when a section of the cell’s plasma membrane encircles the substance, then pinches off into a vesicle that is released into the cell. See also exocytosis.
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Endoderm
the innermost of three germ layers, primitive cell types that develop in the embryo and that will differentiate into the various tissues and organs of the body. See alsoectoderm; germ layers; mesoderm.
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Endotoxins
molecules in the walls of certain Gram-negative bacteria that are released when the bacterium dies or is destroyed, causing toxic (poisonous) effects on the host body.
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Eosinophils
granular white blood cells that attack parasites and also help to control and limit the inflammatory response.
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Epithelial tissue
the protective tissue that lines internal and external body tissues. Examples: skin, mucous membranes, the lining of the intestinal tract.
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Epithelialization
growth of epithelial cells under a scab, separating it from the wound and providing a protective covering for the healing wound.
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Erythrocytes
red blood cells, which contain hemoglobin, which transports oxygen to the cells.
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Etiology
the study of disease causes; the occurrences, reasons, and variables of a disease.
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Eukaryotic cells
cells that contain a nucleus and organelles. The cells of most multicellular organisms, including humans, are eukaryotes. See also prokaryotic cells.
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Exocrine secretions
secreted substances that are deposited on the surface of the skin or other epithelial surface through ducts.
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Exocytosis
process by which substances can exit after being encircled by a membrane vesicle. See also endocytosis.
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Exotoxins
toxic (poisonous) substances secreted by bacterial cells during their growth.
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Exudate
substances that penetrate vessel walls to move into the surrounding tissues.
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Fermentation
the breakdown of glucose without oxygen.
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Fibroblasts
the most abundant cells in connective tissue; cells that secrete collagen proteins that maintain a structural framework for many tissues and play an important role in wound healing.
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Fick principle
principle stating that the overall movement and utilization of oxygen in the body is dependent on five conditions: adequate concentration of inspired oxygen; appropriate movement of oxygen across the alveolar/capillary membrane into the arterial bloodstream; adequate number of red blood cells to carry the oxygen; proper tissue perfusion; and efficient off-loading of oxygen at the tissue level.
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Free radicals
atoms or molecules with an unpaired electron in the outer shell. Most free radicals are highly reactive and cause cell damage, especially oxidative damage.
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Free water
water that is free of solute.
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General adaption syndrome
a sequence of stress response stages: stage I, alarm; stage II, resistance or adaptation; stage III, exhaustion.
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Germ layers
the three primitive cell types (endoderm, ectoderm, mesoderm) that develop in the embryo and that will differentiate into the various tissues and organs of the body. See also ectoderm; endoderm; mesoderm.
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Glycogenolysis
a process controlled by the hormones glucagon and epinephrine in which stores of glycogen are broken down into glucose to meet a bodily need for glucose. See also glycogen.
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Glycolysis
a series of reactions by which a molecule of glucose is converted into two molecules of pyruvic acid, a process that begins the conversion of glucose into energy and that also produces free hydrogen ions that determine the body’s pH.
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Granulation
filling of a wound by the inward growth of healthy tissues from the wound edges.
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Granulocytes
white cells with multiple nuclei that have the appearance of a bag of granules; also called polymorphonuclear cells. Types of granulocytes are neutrophils, eosinophils, and basophils.
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Granuloma
a tumor or growth that forms when foreign bodies that cannot be destroyed by macrophages are surrounded and walled off.
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Half life
a unit of rate of decay of radioactive isotopes; the time it takes for the decaying parent isotope to decrease by half.
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Haptens
molecules that do not trigger an immune response on their own but can become immunogenic when combined with larger molecules.
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Hematocrit
the percentage of the blood occupied by erythrocytes.
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Hemoglobin
an iron-based pigment present in redblood cells that binds with oxygen and transports itto the cells.
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Histamine
a substance released during the degranulation of mast cells and also released by basophils that, through constriction and dilation of blood vessels, increases blood flow to the injury site and also increases the permeability of vessel walls.
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Histopathology
the study of diseased or abnormal tissues.
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HIV
a virus that breaks down the immune defenses, making the body vulnerable to a variety of infections and disorders. (Human immunodeficiency virus)
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HLA antigens
antigens the body recognizes as self or non-self; present on all body cells except the red blood cells.
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Humoral immunity
the long-term immunity to an antigen provided by antibodies produced by B lymphocytes.
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Hypercapnia
an elevated level of plasma CO2.
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Hyperplasia
an increase in the number of cells resulting from an increased workload.
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Hypersensitivity
an exaggerated and harmful immuneresponse; an umbrella term for allergy, autoimmunity, and isoimmunity.
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Hypertrophy
an increase in cell size resulting from an increased workload.
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Hyperventilation
rapid or deep breathing in excess of the body’s needs.
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Hyperventilation syndrome
excessive CO2 elimination resulting in respiratory alkalosis, caused by hyperventilation.
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Hypocapnia
a reduced level of plasma CO2.
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Hypoperfusion
inadequate perfusion of the body tissues, resulting in an inadequate supply of oxygen and nutrients to the body tissues. Also called shock.
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Hypoventilation
reduced rate or depth of breathing that does not meet the body’s needs.
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Hypovolemic shock
shock caused by a loss of intravascular fluid volume.
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Hypoxemia
decreased partial pressure of oxygen in the blood.
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Hypoxia
a general oxygen deficiency or oxygen deficiency to a particular tissue or organ.
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Iatrogenic disease
a disease that results from a medical treatment given for another disease or condition.
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Idiopathic
of unknown cause, in reference to a disease.
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Immediate hypersensitivity reaction
a swiftly occurring secondary hypersensitivity reaction (one that occurs after reexposure to an antigen). Immediate hypersensitivity reactions are usually more severe than delayed reactions. The swiftest and most severe such reaction is anaphylaxis.
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Immune response
the body’s reactions that inactivate or eliminate foreign antigens.
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Immunity
exemption from legal liability; a long-term condition of protection from infection or disease; the body’s ability to respond to the presence of a pathogen.
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Immunogens
antigens that are able to trigger an immune response.
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Immunoglobulins
antibodies; proteins, produced in response to foreign antigens, that destroy or control the antigens.
425
Inflammation
the body’s response to cellular injury; also called the inflammatory response. In contrast to the immune response, inflammation develops swiftly, is nonspecific (attacks all unwanted substances in the same way), and is temporary, leading to healing.
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Insidious
existing without symptoms or with mild symptoms, as a disease that does not seem as serious as it is or as it may become.
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Interstitial fluid
the fluid in body tissues that is outside the cells and outside the vascular system.
428
Irreversible shock
shock that has progressed so far that no medical intervention can reverse the condition and death is inevitable.
429
Ischemia
a blockage in the delivery of oxygenated blood to the cells.
430
Isoimmunity
an immune response to antigens from another member of the same species—for example, Rh reactions between a mother and infant or transplant rejections; also called alloimmunity.
431
Kinin system
a plasma protein system that produces bradykinin, a substance that works with prostaglandins to cause pain. It also has actions similar to those of histamine (vasodilation and bronchospasm, increased permeability of the blood vessels, and chemotaxis) but acts more slowly than histamine, thus being more important during later stages of inflammation.
432
Leukocytes
white blood cells, which play a key role in the immune system and inflammatory (infection-fighting) responses.
433
Leukotrienes
also called slow-reacting substances of anaphylaxis (SRS-A); substances synthesized by mast cells during the inflammatory response that cause vasodilation, vascular permeability, and chemotaxis.
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Lymphocytes
a type of leukocyte, or white blood cell, that attacks foreign substances as part of the body’s immune response.
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Lymphokine
a cytokine released by a lymphocyte.
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Major histocompatability complex
a group of genes on chromosome 6 that provide the genetic code for HLA antigens.
437
Malignant
cancerous; able to spread to other tissues. See also benign.
438
Margination
adherence of white cells to vessel walls in the early stages of inflammation.
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Mast cells
large cells, resembling bags of granules, that reside near blood vessels. When stimulated by injury, chemicals, or allergic responses, they activate the inflammatory response by degranulation (emptying their granules into the extracellular environment) and synthesis (construction of leukotrienes and prostaglandins).
440
Maturation
continuing processes of wound reconstruction that may occur over a period of years after initial healing, as scar tissue is remodeled and strengthened.
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Memory cells
cells produced by mature B lymphocytes that “remember” the activating antigen and will trigger a stronger and swifter immune response if reexposure to the antigen occurs.
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Mesoderm
the middle of three germ layers, primitive cell types that develop in the embryo and that will differentiate into the various tissues and organs of the body. See alsoectoderm; endoderm; germ layers.
443
Metabolic acid-base disorders
metabolic acidosis and metabolic alkalosis; disorders that result from changes in the production of acid or changes in bicarbonate levels within the body.
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Metabolic acidosis
acidity caused by an increase in acid, often because of increased production of acids during metabolism or from causes such as vomiting, diarrhea, diabetes, or medication.
445
Metabolic alkalosis
alkalinity caused by an increase in plasma bicarbonate resulting from causes including diuresis, vomiting, or ingestion of too much sodium bicarbonate.
446
Metallic elements
elements that tend to lose electrons. See also nonmetallic elements.
447
Metaplasia
replacement of one type of cell by another type of cell that is not normal for that tissue.
448
Metastasis
movement of cancer cells to other areas of the body from the original site.
449
Milliequivalents
a unit of measure applied to electrolytes, used as a unit of measure for amounts of very small magnitude.
450
Minute volume
the amount of air (gas) inhaled and exhaled in one minute.
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Monoclonal antibody
an antibody that is very pure and specific to a single antigen.
452
Monocytes
white cells with a single nucleus; the largest normal blood cells. During inflammation, monocytes mature and grow to several times their original size, becoming macrophages.
453
Monokine
a cytokine released by a macrophage.
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Monomer
an atom or a small molecule that may bind chemically to other monomers to form a polymer. See also polymer.
455
Multiple organ dysfunction syndrome
progressive impairment of two or more organ systems resulting from an uncontrolled inflammatory response to a severe illness or injury.
456
Muscle tissue
tissue that is capable of contraction when stimulated. There are three types of muscle tissue: cardiac (myocardium, or heart muscle), smooth (within intestines, surrounding blood vessels), and skeletal, or striated (allows skeletal movement). Skeletal muscle is mostly under voluntary, or conscious, control; smooth muscle is under involuntary, or unconscious, control; cardiac muscle is capable of spontaneous, or self-excited, contraction.
457
Natriuretic peptide
peptide hormones synthesized by the heart, brain, and other organs with effects that include excretion of large amounts of sodium in the urine and dilation of the blood vessels.
458
Natural immunity
inborn protection against infection or disease that is part of the person’s or species— genetic makeup.
459
Neoplasia
abnormal or uncontrolled cell growth. See also neoplasm.
460
Neoplasm
a tumor that results from neoplasia. See also neoplasia.
461
Nerve tissue
tissue that transmits electrical impulses throughout the body.
462
Neurogenic shock
shock resulting from brain or spinal cord injury that causes an interruption of nerve impulses to the arteries with loss of arterial tone, dilation, and relative hypovolemia.
463
Neuroglia
glial cells that support, insulate, and protect neurons.
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Neuron
nerve cell; cell that transmits electrical impulses.
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Neutrophil
a type of white blood cell; a phagocyte that has the ability to ingest other cells and substances.
466
Primary immune response
the initial development of antibodies in response to the first exposure to an antigen in which the immune system becomes “primed” to produce a faster, stronger response to any future exposures.
467
Primary intention
simple healing of a minor wound without granulation or pus formation.
468
Prognosis
the expected outcome of a disease or injury.
469
Psychoneuroimmunological reaction
the interactions of psychological, neurologic/endocrine, and immunologic factors that contribute to alteration of the immune system as an outcome of a stress response that is not quickly resolved.
470
Respiratory acid-base disorders
respiratory acidosis and respiratory alkalosis; disorders that result from an inequality between carbon dioxide generation in the peripheral tissues and carbon dioxide elimination by the respiratory system.
471
Septic shock
shock that develops as the result of infection carried by the bloodstream, eventually causing dysfunction of multiple organ systems.
472
Virus
an organism much smaller than a bacterium, visible only under an electron microscope. Viruses invade and live inside the cells of the organisms they infect.