Quiz 1 Flashcards
(103 cards)
1
Q
total number of circulating WBCs
A
WBC count
2
Q
relative number of each type of WBC present in blood
A
Differential count
3
Q
increased WBC
A
infection, neoplasia, physiologic conditions in newborn
4
Q
immature form of neutrophils
A
bands
5
Q
normal value of segmenters
A
0.50 - 0.70
6
Q
normal value of lymphocytes
A
0.20 - 0.40
7
Q
normal value of eosinophils
A
0-0.5
8
Q
normal value of basophils
A
0-0.01
9
Q
normal value of monocytes
A
0-0.07
10
Q
normal value of bands
A
0-0.07
11
Q
determination of abnormal RBC precursors
A
Bone Marrow Aspirate
12
Q
detect WBC alterations
A
peripheral blood smear
13
Q
uses immune reactions to identify molecules in WBC
A
Immunophenotyping
14
Q
blood cell formation
A
hematopoiesis
15
Q
origin of blood cells
A
pluripotential hematopoietic stem cells
16
Q
most immature cell of the myeloid series
A
myeloblast
17
Q
start of granule formation
A
promyelocyte
18
Q
D shape nucleus
A
myelocyte
19
Q
indented or kidney shaped nucleus
A
metamyelocyte
20
Q
horse shoe or S shaped
A
band cell
21
Q
increased in infections and extreme exercise
A
neutrophils
22
Q
increased in parasitic infections
A
eosinophils
23
Q
linked to IgE
A
basophils
24
Q
releases histamine
A
mast cells
25
most immature cell of the lymphoid series
lymphoblast
26
types of lymphocytes
T and B cells
27
only immature cell that enlarges as it matures at
megakaryoblast
28
largest cell in the bone marrow
megakaryocyte
29
origin of platelets
megakaryocyte
30
Site the most common site of marrow aspiration
ASIS/PSIS
31
1st line of defense of the body
white blood cell
32
normal wbc count
5-10x10^9/L
33
normal neonate WBC count
18x10^9/L
34
effect of exercise to WBC count
increase
35
Decrease in the total leukocyte count
leukopenia
36
percentage of circulating neutrophils
2-3%
37
WBC in the blood vesl walls
marginal pool
38
drugs inducing neutropenia
Chlorpromazine, Phenothiazine and
| Sulfonamides.
39
in viral infections, neutrophils are
decreased
40
increase in circulating leukocytes
leukocytosis
41
leukocytosis without tissue damage
physiologic leukocytosis
42
increased rate of neutrophil inflow from marrow to the circulation
physiologic neutrophilia
43
increased neutrophils from disease
pathologic neutrophilia
44
group of disorder that is
| potentially neoplastic
Myeloproliferative disorder
45
Non-leukemic leukocytosis
Leukemoid reaction
46
Lack of myeloblasts in peripheral blood smear
Leukemoid reaction
47
enzyme from mature WBC
Leukocyte Alkaline Phosphatase (LAP)
48
LAP is increased in what condition?
Leukemoid reaction
49
Most common etiology of lymphocytosis
viral infection
50
occur if the total number of
lymphocytes is elevated, but its proportion is elevated in
proportion to the total WBC count
Relative lymphocytosis
51
occur when the total number
| of lymphocytes is increased in proportion
Absolute lymphocytosis
52
WBC increased in Subacute bacterial endocarditis
monocyte
53
dominant cell causing inflammatory
| response
macrophages
54
WBC increased in type 1 hypersensitivity
basophils
55
Failure Of Normal Segmentation Of Granulocytic Nuclei
Pelger Huet Anomaly
56
Nucleus Shape In Pelger Huet Anomaly
Dumbbell Shaped
57
Non Neoplastic Condition In Severe Infection
Toxic Granulation
58
Remnants Of rER/Free Ribosome
Dohle Body
59
>5 Lobes
Hypersegmented Neutrophil
60
Anemia Associated To HYPERSEGMENTED NEUTROPHIL
Megaloblastic anemia
61
Azurophilic inclusions in the WBC Not related to infection
ALDER REILLY ANOMALY
62
Abnormally large granule in
leukocyte and in other granulecontaining
cell
CHEDIAK-HIGASHI SYNDROME
63
Malignancies of white blood cells in peripheral blood
leukemia
64
Malignancies of white blood cells in lymph nodes
lymphoma
65
T/F Leukemia is always malignant
true
66
leukemia with predominant blast cells
acute leukemia
67
acute leukemia with predominant mature cells
monocytic leukemia
68
Typical picture of leukemia
LEUKEMIC LEUKEMIA
69
leukemia with normal WBC count
SUBLEUKEMIC LEUKEMIA
70
Normal CBC & PBS, changes are found in the bone marrow
ALEUKEMIC LEUKEMIA
71
most common presentation of leukemia
moderate to severe anemia
72
leukemia with normal platelet count
Chronic Myelogenous Leukemia
73
sudan black is positive for AML or ALL?
AML
74
peroxidase is for what series?
myeloid
75
leukocyte-specific estarase is positive for?
all granulocytes
76
positive result of Non-specific Esterase
black granules
77
marker for monocytes
NASD Acetate esterase
78
marker for immature cells
Terminal Deoxynucleotidyl Transferase
79
stain for immature RBCs
Periodic Acid Schiff
80
marker for hairy cell leukemia
Tartrate Resistant Acid Phosphatase
81
Minimally differentiated AML
M0
82
Acute Myelocytic without maturation
M1
83
Acute Myelocytic with maturation
M2
84
Acute Promyelocytic, hypergranular
M3
85
Acute Promyelocytic, hypogranular
M3V
86
Myelomonocytic
M4
87
Myelomonocytic with eosinophilia
M4-Eo
88
Monocytic without maturation
M5A
89
Monocytic with maturation
M5B
90
Erythroleukemia
M6
91
other name of Erythroleukemia
DiGuglielmo’s Syndrome
92
Megakaryocytic
M7
93
LYMPHOBLASTIC LEUKEMIA with Homogenous small blast type
L1
94
LYMPHOBLASTIC LEUKEMIA with Heterogenous blast type
L2
95
LYMPHOBLASTIC LEUKEMIA with Homogenous large blast type
L3
96
L3 resembles what lmphoma
Burkitt’s Lymphoma
97
condition wherein the only cells seen are a combination of myeloblasts and mature neutro
Leukemic hiatus
98
Myeloid Markers
CD 13 and CD33
99
FAB Criteria is based on
Morphology and Cytochemistry
100
MYELOPROLIFERATIVE SYNDROMES have mutations in
tyrosine kinases
101
chromosome seen in CML
PHILADELPHIA CHROMOSOME
102
True increase in RBC mass with underlying cause
SECONDARY POLYCYTHEMIA
103
Contain an acid phosphatase which is resistant to inhibition by L-tartrate
HAIRY CELL LEUKEMIA
