Quiz 1 ID 2-3 Side Effects Flashcards

1
Q

What two drugs causes diarrhea, hypersensitivity, seizures with excessive doses?

What is the class?

A

Carbapenem

  • meropenem (Merrem)
  • ertapenem (Invanz)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What drug class may cause tendinitis/ tendon rupture, peripheral neuropathy, CNS effects, and muscle weakness in patients with myasthenia gravis?

A

Fluoroquinoles

  • ciprofloxacin (Cipro)
  • levofloxacin (Levaquin)
  • moxifloxacin (Vigamox, Avelox)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What drug can cause diarrhea and QTc prolongation?

A
  • azithromycin (Zithromax, Z-Pak, Zmax)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What drug can cause diarrhea, QTc prolongation, AND a metallic taste?

A
  • clarithromycin (Biaxin, Biaxin XL)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which drug do you not use for systemic infections? And why?

A
  • fidaxomicin (Dificid) is not used for systemic infections b/c there is no systemic absorption
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What tetracycline antibiotic causes esophagitis and photosensitivity?

A
  • doxycycline (Vibramycin)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What drug category may cause permanent gray-brown discoloration of teeth or enamel hypoplasia when given to children?

A

Tetracycline Antibiotics

  • doxycycline
  • minocycline
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which antibiotics should you take 2 hours before or 6 hours after products that contains divalent or trivalent cations (ex. Dairy products, calcium juices, oral multivitamins, mineral supplements)?

Hint: Two drug classes

A
  • Tetracycline (2)

- Fluoroquinolone (3)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q
What drug class can cause QTc prolongation, tendon rupture, 
increased hepatic transaminases, photosensitivity?
A

Fluroquinolone (3)

  • ciprofloxacin
  • levoflaxacin
  • moxifloxacin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What drug causes skin rashes, hyperkalemia, increased serum creating, hypersensitivity, nausea, vomiting, diarrhea?

Hint: Combo drug

A

Sulfonamide Antibiotic

- sulfamethoxazole and trimethoprim (Bactrim, Bactrim DS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the ratio of sulfamethoxazole and trimethoprim?

A

Fixed ratio of (5:1); dosing based on trimehtoprim

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What drug when giving in chronic use can cause pulmonary fibrosis?

A

Urinary Antibiotic

- nitrofurantoin (Macrobid)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What drug causes nephrotoxicity and vancomycin infusion reactions?

A

Glycopeptide

-vancomycin (Vancocin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What drug causes alcohol intolerance and with long term use cause peripheral neuropathy?

It also has a metallic taste

A
  • metronidazole (Flagyl)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Does mupirocin (Bactroban) have any major side effects?

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What drug causes abdominal pain, elevated hepatic transaminases, headache, and nausea?

A
  • terbinafine (Lamisil)
17
Q

What drug causes increased hepatic transaminases and crystalluria?

Note: it is a vesicant

A

Antiviral

- acyclovir (Zovirax)

18
Q

What causes increased hepatic transaminases and nausea?

A

Antiviral

- valcyclovir (Valtrex)

19
Q

What drug causes QTc prolongation, elevated hepatic transaminases, nausea, and abdominal pain?

A
  • fluconazole (Diflucan)
20
Q

What drug has a box warning of serious hepatoxicity that can lead to death or requires liver transplantation? Also can lead to QTc prolongation?

A

Azole Antifungal

- ketoconazole (Nizoral)

21
Q

What drug can cause rare neuropsychiatric events in pediatrics?

A

Neuraminidase inhibitor antiviral

- oseltamivir (Tamiflu)

22
Q

Does nystatin have any side effects?

A

No

23
Q

What dosage form should be used for thrush?

A

Oral solution of nystatin

24
Q

What two side effects can occur with nystatin (topical)?

A

Burning and itching

25
Q

What drug causes burning, itching, dryness, and skin atrophy?

You should not use this for diaper dermatitis

Long term use of this can cause adrenal suppression

Hint: drug combo

A
  • betamethasone and clotrimazole (topical)
26
Q

What drugs can cause QTc prolongation?

A
  1. Fluroquinolones ( ciprofloxacin, moxifloxacin, levofloxacin)
  2. Azithromycin
  3. Clarithomycin
  4. Ketoconazole
27
Q

What two drugs have a metallic taste?

A
  1. Clarithomycin

2. Metronidazole