Quiz Flashcards
What does the acronym PICO stand for?
P: Population and Problem
I: Intervention
C: Comparison or Control
O: Outcome
Name the 3 key characteristics in quantitative research
- Process is deductible
- Data is numeric
- Pre-specified methods are used
Name the 4 key objectives of quantitative research
- To predict
- To compare
- To describe
- To evaluate
What does the acronym SPIDER stand for?
S: Sample PI: Phenomenon of Interest D: Design E: Evaluation R: Research Type
What is the definition of internal validity?
Level to which independent variable caused the outcome of the study. In other words, is your outcome actually measuring what was intended to measure?
Name the 5 Steps of EBM
- Ask a clinical question
- Acquire the best evidence
- Appraise the evidence
- Apply the evidence
- Assess your performance
Why is ethics so important?
To protect research participants from harm: Physical, psychological.
In accordance with the Declaration of Helsinki.
Moral responsibility of researchers. Insurance for researchers.
Explain what is beneficence for ethics
The intention of a study: to do good, and not waste the participants time. The rights of the individual > the greater good.
Give 3 examples of bias
Researchers Bias:
- Components of the environment and/or setting.
- Individual participants and/or sample.
- How groups were formed.
Measurement tools:
- Data collection process.
- Data and duration of study.
- Statistical tests and analysis interpretation.
Name the 6 basic principals of ethics
- Autonomy
- Non-Maleficence
- Beneficence
- Justice
- Confidentiality
- Dissipation of knowledge
Name the 3 boolean operators you can use while doing a PUBMED search
- AND
- OR
- NOT
TRUE/FALSE. Patients are always allowed to withdraw from a trial except during the first 48h after signing informed consent.
False
TRUE/FALSE. The acronym SPIDER is used for defining keywords in mixed methods research.
True.
TRUE/FALSE. In qualitative research, the purpose is a deep understanding of a phenomenon.
True.
TRUE/FALSE. External validity refers to weather the results of a study can be extra-polated to other populations than the ones that were studied.
True.
TRUE/FALSE. Efficacy refers to the extent to which an intervention produces a beneficial outcome under day to day circumstances.
False.
TRUE/FALSE. Efficiency refers to the extent to which the balance between input (costs) and outputs (outcomes) on interventions represents value for money.
True.
TRUE/FALSE. Effectiveness refers to extent to which intervention produces beneficial outcomes under ideally controlled/laboratory circumstances.
False.
TRUE/FALSE. In the hierarchy of scientific evidence, Systematic review are ranked higher than Randomized control trial.
True.
TRUE/FALSE. In the hierarchy of scientific evidence, in vitro studies are the highest ranked.
False.
Name the different strategies that can be used in a PUBMED search.
- Boolean operators
- Alternative word strategy
- Truncation strategy
- MeSH terms
- Quotation mark strategy
Name 3 components of a critical appraisal of a quantitative research.
- Was the purpose stated clearly?
- Was relevant background literature reviewed?
- What is the study design?
- Was the sample described in detail?
- Was sample size justified?
- Were outcome measures reliable/valid?
- Intervention described in detail?
- Contamination avoided?
- Co-intervention avoided?
- Results were reported in terms of statistical significance?
- Were the analysis methods appropriate?
- Clinical importance was reported?
- Conclusions were appropriate given study methods and results?
What are the components of an ethical approval request?
- Detailed study outline/proposal.
- Participant information sheet.
- Informed consent form.
- Participant debrief.
- Secondary info, such as outcome measures.
- Budget planning.
Define anecdotal evidence
Evidence collected in a casual or informal manner and relying heavily or entirely on personal testimony: Story told by individuals.
Many forms from product testimonials to word to mouth.
Driven by emotions, and presented by individuals who are not subject area experts.