Quiz 2

Question 0

Definition of pharmacotherapeutics

Answer 0

Study of meds affect patient

Question 1

What is pharmacology?

Answer 1

Study of how substances affect living tissue, including how these agents bind to receptors to enhance or inhibit fcn

Question 2

Definition of pharmacodynamics

Answer 2

What the drug does to the body

Question 3

study of pharmacokinetics

Answer 3

Study of the bodies effect on the drug

Question 4

Name of the drug in Dr. Breslin’s lawn that can kill you if you eat it

Answer 4

Digitalis

Question 5

Name of the drug that is found to be good for brain tumors

Answer 5

Thalidomide

Question 6

FDA approval process: Preclinical work

Answer 6

Drug tested on animal models

Question 7

FDA approval process: Phase 1

Answer 7

Drug tested on healthy human volunteers

Question 8

FDA approval process: Phase 2

Answer 8

Drug tested on Small groups of people who have the disease for which the drug is thought to be of use

Question 9

FDA approval process: Phase 3

Answer 9

Larger groups of individuals are studied taking the drug.

The FDA can improve a drug for marketing at this stage

Question 10

FDA approval process: Phase 4

Answer 10

Post market studies and surveillance to further determine efficacy and safety

Question 11

Name of act which was instilled in 1970 which helped control drugs on the market

Answer 11

The comprehensive drug abuse prevention and control act of 1970

Question 12

What is a schedule 1 drug

four examples

Answer 12

Highest potential for abuse and most addictive

Ecstasy LSD marijuana heroin

Question 13

What is a schedule 2 drug

some examples

Answer 13

has high potential for abuse and addiction

pure stimulant or pure opiate such as oxycodone hydromorphone morphine Dexedrine

Question 14

What is a schedule III drug?

Examples?

Answer 14

Less potential for abuse and addiction and schedule I and II

Combo drugs such as anabolic steroids hydrocodone/acetaminophen and codeine/acetaminophen

Question 15

What is a schedule IV drug

Some examples

Answer 15

Less addictive and potential for abuse than schedule III

Examples include Valium Ativan Xanax Ambien and sonata

Question 16

What is a schedule V drug

some examples

Answer 16

The absolute least addictive of all known drugs

Cough syrups containing Codeine

Question 17

How are drugs classified for pregnant people

Answer 17

Category A-ok (best),
B good (most common)
category X dangerous

Question 18

What is a chemical name?

Answer 18

Scientific name describing molecular structure

Question 19

What is a generic name, example?

Answer 19

Nonproprietary name which is usually an abbreviation of the chemical structure
Acetaminophen

Question 20

What is a brand or trade name

Some examples?

Answer 20

The marketing team selected by the drug company

Advil and Tylenol

Question 21

What is a drug class

Answer 21

Family name of that drug and drugs of similar chemical structure and function

Question 22

what is a PDR?

Answer 22

Physicians desk reference

They are now sleeves within drug containers which describes the precautions and Contraindications of drugs

Question 23

Order of how drugs go through the human body (5)

Answer 23

Administration, absorption, Distribution, metabolism, elimination

Question 24

What is the fastest method of drug administration? what is the slowest method?

Answer 24

IV fastest method | Oral tab slowest method (first pass)

Question 25

Injections via (deltoid) muscle or (gluteal) fat faster administration

Answer 25

Kicks in faster in the deltoid muscle than in the fat of the glute region

Question 26

Drugs which are acids prefer what kind of environment Drugs which are basic prefer which kind of environment examples of both

Answer 26

Acid likes acid Base Likes Base the stomach is an example of acid Intestines are an example of basic

Question 27

What kind of drugs pass best through the brain and fetus

Answer 27

Lipid soluble

Question 28

What is a substrate?

Answer 28

A substance that is affected by an enzyme

Question 29

What does a drug inhibitor do?

Answer 29

Decreases enzyme so less substrate is metabolized | Increases the effact of substrates

Question 30

What are the effects of drug inducers?

Answer 30

Increases the enzyme and increases metabolism of the substrate Decreases affect of substrate

Question 31

How many half-lives does it take to get a drug completely out of the system

Answer 31

Five

Question 32

If the half-life of a drug is 15 hours what is the calculation and how long will it take it to leave the body?

Answer 32

15 hours times 5 equals 75 hours to leave the body

Question 33

Receptors function like a ________ that opens a neural path when the proper ligand is inserted

Answer 33

Keyhole

Question 34

Correct order of what occurs at the site of drug action (4)

Answer 34

Synthesis, release, interactions, transmitter effects

Question 35

In order for an action potential to occur what mineral is needed to power it

Answer 35

Calcium

Question 36

What is a drug receptor affinity

Answer 36

the attractiveness of drug and receptor | Whichever drug has an higher affinity will gain the slot

Question 37

Agonist drugs have two of which characteristics

Answer 37

Affinity and efficacy

Question 38

What is an antagonist drug

Answer 38

Interact with the receptor but do not change it Have affinity but no efficacy

Question 39

What is a competitive antagonist?

Answer 39

Competes with agonist for receptor, however once it is in the receptor no function occurs until the cell dies

Question 40

The greater the therapeutic index is the drug more lethal or safe?

Answer 40

The greater the therapeutic index the more safe the drug | the more narrow the index the more dangerous the drug