Quiz 2 Flashcards

(30 cards)

1
Q

what is differentiation?

A

the process by which adult cells’ cell types (neuron, muscle cell, etc.) are decided

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2
Q

differentiation is/not reversible in vivo

A

not

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3
Q

what is hCG?

A

hormonal signal produced by the fertilized egg to signal to the ovaries that fertilization has occurred

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4
Q

how does hCG prevent menstruation?

A

mains the ovarian production of progesterone

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5
Q

weeks 0-7 characteristics

A
  • mainly internal development; not much external development
  • primordial lungs, muscles and other structures later become those structures, but reproductive structures can go on to become ovaries or testes
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6
Q

weeks 0-7 kick-off event

A

the migration of primordial germ cells from the yolk sac to the genital ridges (weeks 4/5)

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7
Q

testosterone production promotes _______ duct differentiation into epididymis & vas deferens

A

mesonephric

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8
Q

anti-mullerian hormone (AMH) definition

A

prevents the development of paramesonephric ducts

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9
Q

in the absence of testosterone, __________ ducts degrade

A

mesonephric

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10
Q

weeks 8-12 characteristics

A
  • cell differentiation begins
  • if present, SRY genes will activate
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11
Q

weeks 12-20 characteristics

A
  • Sertoli and Lydia cells will develop in the presence of SRY signals
  • in the absence of SRY signals, hymen, the lower vagina, ovaries, and oocytes develop
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12
Q

estrogen and testosterone are secreted by the

A

gonads

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13
Q

where is testosterone converted into estrogen?

A

bone tissue

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14
Q

what enzyme converts testosterone into estrogen?

A

aromatase

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15
Q

at the start of puberty, the hypothalamus and anterior pituitary become ____ sensitive to negative feedback signals

A

less

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16
Q

at the start of puberty, GnRH begins to be secreted at _____ levels

17
Q

LH and FHS levels increase, which leads to a(n) ________ in testosterone and estrogen levels

18
Q

in early stages of puberty, estrogen (or testosterone converted to estrogen) levels are ___ enough to promote bone growth

19
Q

in early stages of puberty, estrogen (or testosterone converted to estrogen) levels are ___ enough to promote growth plate fusion

20
Q

sperm exit route

A
  1. produced in the testes
  2. epididymis (maturation)
  3. vas deferens (ductus deferens)
  4. prostatic urethra
  5. membranous urethra
  6. spongy urethra
21
Q

androgen receptor (AR) gene is carried on the _______

22
Q

ARs are expressed in the highest concentrations in the _______

A

reproductive organs and gonads

23
Q

AR in testes

A
  • expressed on nurse and interstitial cells
  • plays a role in sperm development
24
Q

AR in ovaries

A
  • expressed on follicles
  • plays a role in follicular development
25
estrone is prominent
after menopause
26
estradiol is prominent
in non-pregnant people
27
estriol is prominent
in pregnancy
28
estetrol is produced
only during pregnancy
29
ER alpha expression
- endometrium - breast cancer cells - ovarian stromal cells - hypothalamus - efferent ducts within the testes
30
ER beta expression
- ovarian follicle cells - kidney - brain - bone - heart - intestines - prostate - endothelium