Quiz 2 Flashcards
metabolic pathways
coordinated series of reactions that convert molecules into different one
Five principles of metabolic pathways
1) Complex transformations occur in a series of separate reactions. 2) Each reaction catalyzed by enzyme. 3) Many metabolic pathways are conserved across countless organisms. 4) In eukaryotes, metabolic pathways are compartmentalized in specific organelles (why they are larger). 5) Key enzymes in each pathway can be regulated (metabolism occurs within cells). Each pathway can be inhibited or activated.
Anabolic
Simple molecules built up into more complex ones (endergonic)
Catabolic
Complex molecules built down into smaller molecules (exergonic). Energy harnessed back into ATP.
ATP structure
sugar (ribose), base (Adenine), phosphate. Nucleotide holds energy.
Phosphate Groups
Phosphate groups have negative charges so when brought together they repel each other (they need lots of energy to break). When broken they will release a lot of energy. 3 Phosphate groups
ADP
when theres only two phosphate groups (one broke down)
AMP
When there is only one phosphate group (
Hydrolysis
addition of water. ATP+H20–> ADP +Pi (the Pi is the phosphate group that had their bond broken). Exergonic reaction because energy is being released from broken bond of phosphate group.
What is ATP+H20–> ADP +Pi catalyzed by?
ATPase
Exergonic reactions
Releases energy which can be harnessed to make ATP.
Endergonic reactions
requires energy from ATP
Coupling
Coupling exergonic reactions with endergonic. Energy from exergonic reaction drives endergonic reaction.
Is the same phosphate broken down in exergonic reactions being used in endergonic reactions?
No, there are a bunch of different phosphates floating around so there will be different phosphates being used
reduction
gain of one or more electrons (RIG)
oxidation
loss of electrons (OIL)
redox reactions
one substance transfers electrons to another substance be able to label oxidation and reduction compounds. Reduced electron carriers capture and transfer energy.
How do you keep track of electrons moving?
Whenever an electron is being moved it will go along with a Hydrogen ion. Transfer of hydrogens=transfer of electrons
Coenzyme NAD+
electron carrier in redox reactions. They carry energy in cells which means that they have high energy. This is reversible.
cellular respiration
metabolic pathway to release energy from carbon bonds with the END GOAL of generating ATP. That ATP will be used to drive the rest of reactions within cells
Mitochondrial structure
2 membranes (outer membrane and inner membrane). Squiggles are foldings of inner membrane.
glycolysis
breaks up one glucose to two pyruvate. 10 separate reactions which takes place in the cytosol. for one glucose, 2 molecules of pyruvate are produced. Produces 4 ATP and 2 NADH (2 net ATP). Takes place in cytoplasm
Glycolysis Steps 1-5
Energy investing reactions (put energy in). Put a phosphate group on glucose with 6 carbon and break it into 2 Pyruvate molecules (3 carbon each)
Glycolysis Steps 6-10
yield NADH and ATP (energy harvesting). Pulling energy out (NAD+ to NADH) from each molecule. Receive an ATP from each as well. Then form to 3 carbon molecules