Quiz 2 Flashcards
What is not a specific criterion for classifying a substance as a neurotransmitter?
Ability of the substance to travel long distance between the site of origin and target area
What is not a catecholamine neurotansmitter?
Serotonin (dopamine, epinephrine, noreponepherine)
What is not a monamine transmitter?
Acetylcholine (dopamine, serotonin, epinepherine,)
What is not an amino acid neurotransmitter?
Dopamine (Glutamate, GABA, glycine)
What neurotransmitter is found in nuclei of the basal forebrain?
Acetycholine (dopamine, norepinephrine, serotonin)
The dopamine neural pathway from the ___ to the nucleus accumbens appears to be involved in the experience of reward
ventral tegmental area
A major site of origin of projections using the neurotransmitters serotonin is the
raphe nucleus
A major site of origin of projections using the neurotransmitters norepinephrine is the
locus coeruleus
Noradrenergic axons project into the
all of the above (limbic system, thalamic nuclei, cerebral cortex)
Drugs that mimic GABA receptors might be effective in treating
anxiety disorders
In the mamalian brain, the major inhibitory neurotransmitter is
GABA
the NMDA receptor is a type of receptor for the neurotransmitter
glutamate
GABA receptors are
inhibitory
If drug A is found to bind to a certain type of receptor more strongly than drug B, then drug A is said to have greater
affinity
Higher doses of a drug tend to increase the proportion of receptors that bound and affected by the drug, thereby increasing the response. this relationship is called the
dose- response curve
People who have used a particular dose of a drug several times may develop a similar response to the same dosage of other drugs in the same class. this is an example of
cross tolerance
repeated exposure to a drug leading to a decrease in physiological response is called
tolerance
selective serotonin reuptake inhibitors (SSRIs) work by
allowing transmitter to accumulate in the synaptic cleft
curare is a drug that selectively blocks receptors for
acetycholine
the antipsychotic drug haloperidol is practically selective for dopamine ___ receptors
D2
Most antipsychotic medications act by blocking ____ receptors
dopaminergic
Bensodiazepines appear to modulate the activity of receptors for the neurotransmitter
GABA
Alcohol alters the functioning of the brain via interaction with
GABA receptors
The main active ingredient found in marijuana is
delta 9 tetrahydrocannabinol (THC)