Quiz 3

Question 1

bleeding from anticoagulation (coagulation + hematology labs)

Answer 1

INR, aPTT, Hgb, PLTs

Question 2

synthetic function (coagulation + LFT labs)

Answer 2

PT/INR, aPTT

Question 3

LFT (hepatocellular injury)

Answer 3

ALT, AST

Question 4

excretory function (LFTs)

Answer 4

bilirubin, ALP, GGT

Question 5

detoxification

Answer 5

ammonia

Question 6

synthetic function

Answer 6

albumin

Question 7

infection (hematology)

Answer 7

WBC

Question 8

Anemia hemorrhage (hematology)

Answer 8

RBCs, Hgb, HCt, MCV, MCHC, retics

Question 9

Hemolysis (hematology)

Answer 9

RBCs, Hgb, Hct, bilirubin, haptoglobin

Question 10

leukocytosis

Answer 10

high WBC

Question 11

leukopenia

Answer 11

low WBC

Question 12

most common WBC; fights bacterial and fungal infections by phagocytosis of foreign particles

Answer 12

neutrophils

Question 13

leukopenia or leukocytosis: bone marrow suppression from chemotherapy or drugs

Answer 13

leukopenia

Question 14

leukopenia or leukocytosis: infection or corticosteroid use

Answer 14

leukocytosis

Question 15

erythrocytosis

Answer 15

high RBC count

Question 16

___ are produced in the bone marrow. Transports oxygen to all organs. Life span is approx. 3 months

Answer 16

RBCs

Question 17

which of the following components of CBC is a direct indicator of the oxygen carrying capacity of the blood?
a. RBCs
b. hematocrit
c. hemoglobin
d. WBCs

Answer 17

Hemoglobin

Question 18

MCV

Answer 18

mean corpuscular volume

Question 19

high MCV

Answer 19

macrocytic

Question 20

normal MCV

Answer 20

normocytic

Question 21

low MCV

Answer 21

microcytic

Question 22

which is more clinically useful, MCH or MCHC?

Answer 22

MCHC

Question 23

high MCH/MCHC

Answer 23

hyperchromic

Question 24

normal MCH/MCHC

Answer 24

normochromic

Question 25

low MCH/MCHC

Answer 25

hypochromic

Question 26

__ most useful of RBC indices- used in morphologic classification for anemia

Answer 26

MCV

Question 27

__ is useful to identify hypochromia which indicates Hgb synthesis

Answer 27

MCHC

Question 28

Anemia of chronic disease presents as ___, ___

Answer 28

normocytic, hypochromic

Question 29

iron deficiency causes

Answer 29

microcytic cells (low MCV)

Question 30

anemia of chronic disease/inflammation, hemolysis, hemorrhage causes

Answer 30

normocytic cells (normal MCV)

Question 31

vitamin B12 deficiency, folate deficiency causes

Answer 31

macrocytic cells (high MCV)

Question 32

T/F : elevation of RDW helps with the variability of the cells and helps with the diagnosis of mixed anemia

Answer 32

T

Question 33

reticulocytopenia

Answer 33

low reticulocyte count

Question 34

reticulocytosis

Answer 34

high reticulocyte count

Question 35

causes of reticulocytopenia or reticulocytosis: untreated iron deficiency anemia

Answer 35

reticulocytopenia

Question 36

causes of reticulocytopenia or reticulocytosis: hemolysis, hemorrhage, response to treatment of iron, B12 or folate

Answer 36

reticulocytosis

Question 37

decrease in reticulocytes indicates that the bone marrow is not producing enough __ from either not being stimulated or being suppressed

Answer 37

RBCs

Question 38

used for monitoring response to treatment of anemia (efficacy)

Answer 38

reticulocytes

Question 39

PLT count is critical for __ and monitoring safety of certain medications

Answer 39

clot formation

Question 40

thrombocytopenia

Answer 40

low PLT count

Question 41

thrombocytosis

Answer 41

high PLT count

Question 42

causes of thrombocytopenia or thrombocytosis: - drug induced (e.g. heparin) - cirrhosis - intracranial hemorrhage - petechiae - infection - stress

Answer 42

thrombocytopenia

Question 43

causes of thrombocytopenia or thrombocytosis: - microcirculatory disturbances (headache, paresthesias) - splenectomy (no spleen) - thrombosis - infection

Answer 43

thrombocytosis

Question 44

T/F: heparin induced thrombocytopenia (HIT) is commonly manifests as thrombosis and no bleeding)

Answer 44

true

Question 45

anti seizure meds that can cause thrombocytopenia

Answer 45

carbamazepine and valproic acid

Question 46

__ is important in DNA synthesis, neurologic function and hematopoiesis. deficiency in tissues can exist prior to low serum levels. Intrinsic factor is necessary for active absorption in the GI.

Answer 46

B12 (cobalamin)

Question 47

__ is necessary for DNA synthesis.

Answer 47

folate

Question 48

- pernicious anemia - GI abnormalities - low intake - drug induced are causes of decreased serum __

Answer 48

B12

Question 49

__ is used to identify etiology of macrocytic anemia

Answer 49

B12

Question 50

t/f: if pts serum B12 is less than 400, then the pt has vitamin b12 deficiency

Answer 50

true

Question 51

- poor nutrition - drug induced - alcohol use disorder - pregnancy - GI abnormalities are causes of decreased serum __

Answer 51

folate

Question 52

a. serum iron b. serum ferritin c. total iron binding capacity (TIBC) d. transferrin saturation (TSAT) which is the most useful for iron tests?

Answer 52

serum ferritin

Question 53

which component of the iron studies is an accurate reflection of total body iron stores? a. serum iron b. ferritin c. TSAT d. TIBC

Answer 53

ferritin

Question 54

which component of the iron studies is an accurate reflection of the amount of iron is readily available for erythropoiesis? a. serum iron b. ferritin c. TSAT d. TIBC

Answer 54

TSAT

Question 55

TIBC is an indirect measure of ___

Answer 55

transferrin

Question 56

decrease of these components of the iron studies lead to iron deficiency a. TIBC b. TSAT c. ferritin d. serum iron

Answer 56

serum iron ferritin tsat

Question 57

decreased TIBC is caused by

Answer 57

chronic disease/inflammation

Question 58

increased TIBC is caused by ____

Answer 58

iron deficiency

Question 59

increased TSAT is caused by

Answer 59

iron overload

Question 60

cause of vitamin B12 deficiency (microcytic, macrocytic or normocytic)

Answer 60

macrocytic

Question 61

cause of folate deficiency (microcytic, macrocytic or normocytic)

Answer 61

macrocytic

Question 62

cause of iron deficiency (microcytic, macrocytic or normocytic)

Answer 62

microcytic

Question 63

anemia of chronic inflammation, acute blood loss or hemolysis (microcytic, macrocytic or normocytic)

Answer 63

normocytic