Quiz #3 Flashcards
(43 cards)
What is a Nephron?
basic structural unit of the kidney
What are the 3 portions of the Nephron?
- glomerulus
- Cortex
- Medulla
What is the function of the glomerulus?
Filtration
The cortex contains 2 tubules.
- Proximal Tubule
2. Distal Convoluted Tubule
Where is the Loop of Henle & the Collecting tubule located?
Medulla
Renal epithelial cells are “________” cells
polarized
Renal epithelial contains 2 membranes
- apical membrane
2. basolateral membrane
The apical membrane faces
the nephron lumen
The basolateral membrane faces
the interstitium, capillaries
The Loop of Henle contains Two limbs
- Thin Descending limb
2. Thick Ascending limb
The glomerulus’ primary function is to filter_______
blood
Which tubule is responsible for majority of reabsorption? (glucose, Na, K, Ca, Mg, NaHCO3)
Proximal tubule
The thin descending portion of the Loop of Henle functions to reabsorb _______
water
The thick ascending portion of the Loop of Henle functions to reabsorb _______
15-25%, Na, K, Cl, Ca, Mg
Which tubule is responsible for the re-absorption of Na, & Cl only?
The distal convoluted tubule
The cortical Collecting duct/tubule system functions to?
Na re-absorption & K/H secretion
Carbonic Anhydrase Inhibitor Diuretics act on what area of the Nephron?
Proximal tubule
Thiazide diuretics act on what area of the Nephron?
Distal Convoluted tubule
Where do Osmotic diuretics act in the Nephron?
Primary site: Thin descending Limb of henle
Secondary site: Proximal tubule
Which limb do the Loop diuretics act on?
The thick ascending limb of henle
K+ sparing diuretics & V2 receptor antagonists act on which area of the Nephron?
Cortical Collecting duct system
Osmotic Diuretics ____ interact with receptors or directly block renal transport
Do NOT
The activity of osmotic diuretics is _______ on development of osmotic pressure
Dependent
Osmotic Diuretics are______ filtered through_____
Freely, glomerulus
