quiz 3 and 4 Flashcards
The study of the movement of drugs through the body is termed:
Pharmacokinetics
The study of how a drug interacts with a receptor is termed:
Pharmacodynamics.
Drawback(s) to intravenous injection, as opposed to other forms of administration, of drugs include
the greatest risk of blood clots.
1) Rapid rate of absorption leaves little time to respond to an unexpected drug reaction or accidental overdose
2) Administration by injection requires the use of sterile techniques.
3) Once a drug is administered by injection, it cannot be recalled.
“Biotransformation” is carried out by the ______________ and usually makes a drug ___________.
liver; more water soluble
The time to reach “steady-state” concentrations of a drug (the level of drug achieved in blood with
repeated, regular-interval dosing) is:
achieved when the amount of drug administered equals the amount eliminated.
A drug that blocks the effect of, and occupies the same receptor site as, the naturally occurring compound
is termed:
an antagonist.
Exposure to a drug that inhibits the breakdown of a neurotransmitter (NT):
May cause panic attacks common for MAOI’s.
The intensity of a drug’s effect is proportional to:
the “fit” of the drug to the receptor and the percentage of receptors occupied by the drug.
Potency refers to
the absolute number of molecules of drug required to elicit a response
The therapeutic index refers to the
relative safety of the drug.
“Negative reinforcement” refers to the reinforcing effect that follows the removal or avoidance of an
aversive stimulus. Negative reinforcement thus explains:
the motivation to re-administer a drug when physically dependent.
The cytochrome P450 (CYP450) enzyme family in a hepatocyte:
is typically capable of metabolizing a wide variety of drugs.
the study of how drugs specifically affect brain and
behavior.
Psychopharmacology:
