Quiz 5 SG Flashcards

1
Q

The six layers of laminar organization of the neo cortex, in order, are:

1) __________
2) outer _________
3) outer __________
4) inner __________
5) inner __________
6) __________

A

The six layers of laminar organization of the neo cortex, in order, are:

1) molecular
2) outer granular
3) outer pyramidal
4) inner granule
5) inner pyramidal
6) multiform

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2
Q

__________ is the AP’s of one or a few pre-synaptic neurons that trigger multiple post-synaptic neurons. Found in cerebellum and are common in cortical cells

___________ is where multiple synapses occur on one post-synaptic dendrite

___________ __________ is when two axonic synapses are in sequence and an inhibitory effect occur on the postsynaptic membrane on the third axon.

A

Divergence is the AP’s of one or a few pre-synaptic neurons that trigger multiple post-synaptic neurons. Found in cerebellum and are common in cortica cells

Convergence is where multiple synapses occur on one post-synaptic dendrite

Presynaptic inhibition is when two axonic synapses are in sequence and an inhibitory effect occure on the postsynaptic membrane on the third axon.

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3
Q

Two kinds of summation may occur in convergence:

__________ __________, where the effect of the neurotransmitter _____ be enhanced. Possibilities include all synapses become excitatory which strengthen the signal, or excitatory and inhibitory signals cancel eachother out.

__________ ___________, where varied sites of synapse along the dendritic surface of a neuron causes responses to rise in different parts of the neuron

A

Two kinds of summation may occur in convergence:

Temporal summation, where the effect of the neurotransmitter may be enhanced. Possibilities include all synapses become excitatory which strengthen the signal, or excitatory and inhibitory signals cancel eachother out.

Spatial summation, where varied sites of synapse along the dendritic surface of a neuron causes responses to rise in different parts of the neuron

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4
Q

The smallest functional unit within the dendritic tree is the dendritic _______.

A typical _________ neuron is divided into two parts, ________ and _______ dendritic trees. Found in the ___________, basal ganglia, and the ________

A

The smallest functional unit within the dendritic tree is the dendritic spine.

A typical cortical neuron is divided into two parts, apical and basal dendritic trees. Found in the cerebellum, basal ganglia, and the cortex

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5
Q

A human brain has about ____ billion ________ and ___ trillion _________

A

A human brain has about 100 billion neurons and 60 trillion synapses

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6
Q

PDP, or _________ _________ _________ (neural network theory) tells us that circuits of neurons work thru joint interaction with millions of other neurons. The two kinds of networks are _____-associator and ________-associator. These networks work in parallel so that information processed is thought to be stored in the multitude of ___________ rather than the ________ themselves. Thus, a loss in one component results in reduced ability, not a complete inability to process.

The reduction in performance of this system is called _________ ___________

A

PDP, or Parallel distributed processing (neural network theory) tells us that circuits of neurons work thru joint interaction with millions of other neurons. The two kinds of networks are auto-associator and pattern-associator. These networks work in parallel so that information processed is thought to be stored in the multitude of connections rather than the neurons themselves. Thus, a loss in one component results in reduced ability, not a complete inability to process.

The reduction in perforance of this system is called graceful degredation

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7
Q

The limitations of the __________ model of language include certain features of aphasic syndromes are __________, aphasic cases sometimes occur that aren’t predicted by the model, and sometimes expected __________ do not appear when an adequate lesion exists.

A

The limitations of the Geschwind model of language include certain features of aphasic syndromes are unexplained, aphasic cases sometimes occur that aren’t predicted by the model, and sometimes expected symptoms do not appear when an adequate lesion exists.

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8
Q

An _________ stroke can eaither be caused by a _________ (stationary collection of fat and blood blocking the artery) or an __________ (blood clot contaning arterial debris that travels and gets stuck)

A ____________ stroke is when blood leaks out of a vessel damaging or killing brain tissue.

A

An ischemic stroke can eaither be caused by a thrombus (stationary collection of fat and blood blocking the artery) or an embolism (blood clot contaning arterial debris that travels and gets stuck)

A hemmorrhagic stroke is when blood leaks out of a vessel damaging or killing brain tissue.

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9
Q

_________ are abnormal masses of tissue. A ________ is a general name for a tumor arising from the supportive tissues of the brain. Most common are _____cytomas, ependymomas, ________glimoas, and _________ astrocytomas. ________ tumors do not spread, __________ tumors are graded 1-4, indicating its tendency to spread.

A

Neoplasms are abnormal masses of tissue. A glioma is a general name for a tumor arising from the supportive tissues of the brain. Most common are astrocytomas, ependymomas, oligodendroglimoas, and fibrillary astrocytomas. Benign tumors do not spread, malignant tumors are graded 1-4, indicating its tendency to spread.

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10
Q

Aphasia is an impairment due to acquired and recent damage of the ____, of the ability to comprehend and formulate _________. It is a __________ disorder represented by a variety of impairments in _________ comprehension, reading, oral-_________ language, and writing. The disrupted language may be influenced by __________ inefficiency or impaired _________, but it cannot be explained by _________, sensory loss or _______ dysfunction

A

Aphasia in an impairment due to acquired and recent damage of the CNS, of the ability to comprehend and formulate language. It is a multimodality disorder represented by a variety of impairments in auditory comprehension, reading, oral-expressive language, and writing. The disrupted language may be influenced by physiological inefficiency or impaired cognition, but it cannot be explained by dementia, sensory loss or motor dysfunction

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11
Q

The four language modalities are __________, __________, _________, and _________.

A

The four language modalities are speaking, understanding, reading, and writing.

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12
Q

Dichotomous classification of aphasia is composed of expressive aphasia, associated with _________ lesions and receptive aphasia, associated with _________ lesions.

Ie; Motor aphasia has an anterior cortical pathology in the _________ lobe and sensory aphasia has an posterior lesion in the _________ lobe

A

Dichotomous classification of aphasia is composed of expressive aphasia, associated with anterior lesions and receptive aphasia, associated with posterior lesions.

Ie; Motor aphasia has an anterior cortical pathology in the frontal lobe and sensory aphasia has an posterior lesion in the temporal lobe

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13
Q

Aphasia Syndromes

Non-fluent

________

Transcortical _______

Global

_______ nonfluent

Fluent

Wernicke’s

Transcortical _________

_________

Anomic

___________ aphasias (borderline fluent)

A

Aphasia Syndromes

Non-fluent

Broca’s

Transcortical motor

Global

Mixed nonfluent

Fluent

Wernicke’s

Transcortical sensory

Conduction

Anomic

Subcortical aphasias (borderline fluent)

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14
Q

Aphasic errors

Paraphasias:

Literal or _________ – sound errors, sound transpositions in words (shooshbruss for toothbrush)

Verbal or _________ – semantically related word is substituted (e.g., fork for spoon)

_________ paraphasias – substituted word has no clear relationship to target (e.g., car for hat)

__________ –repetitive use of words. words are involuntarily and are incorrect for target

_________ - inability and/or impairment of ability to retrieve words.

___________ – intentionally speaking around the target word due to inability to retrieve word; common behavior in context of anomia

A

Aphasic errors

Paraphasias:

Literal or phonemic – sound errors, sound transpositions in words (shooshbruss for toothbrush)

Verbal or semantic – semantically related word is substituted (e.g., fork for spoon)

Unrelated paraphasias – substituted word has no clear relationship to target (e.g., car for hat)

Perseveration –repetitive use of words. words are involuntarily and are incorrect for target

Anomia - inability and/or impairment of ability to retrieve words.

Circumlocution – intentionally speaking around the target word due to inability to retrieve word; common behavior in context of anomia

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15
Q

Agrammatism (assoc. w/nonfluent)

use of mostly __________ words (e.g. nouns)

short phrases, e.g. “telegraphic utterances”

__________ words omitted;

selective impairment of ability to retrieve and use _______ as opposed to nouns

Paragrammatism (assoc. w/fluent)

grammatical errors such as wrong _______ markers and misuse of _________ among range of syntactical constructions

A

Agrammatism (assoc. w/nonfluent)

use of mostly substantive words (e.g. nouns)

short phrases, e.g. “telegraphic utterances”

function words omitted;

selective impairment of ability to retrieve and use verbs as opposed to nouns

Paragrammatism (assoc. w/fluent)

grammatical errors such as wrong tense markers and misuse of pronouns among range of syntactical constructions

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16
Q

__________aphasia (broken, nonfluent)

Characteristics:

Phrase length =0-5 words per breath unit

Relatively good _________ comp

Relatively poor __________

A___________

Effortful articulation, disrupted _________

Phonemic paraphasias common

Lesion site: Frontal operculum, surrounding tissue, inferior frontal gyrus

___________ aphasia (wacky, fluent)

Characteristics:

Notable _________

Poor __________ comprehension

Prosody WFL

Articulation WFL

Error types:

Phonemic, semantic, neologistic paraphasias

Empty _________

May have _________

Press of _________

Lesion site: Involves classic Wernicke’s area, posterior temporal gyrus, posterior section of middle and inferior temporal gyri

A

Broca’s aphasia (broken, nonfluent)

Characteristics:

Phrase length =0-5 words per breath unit

Relatively good auditory comp

Relatively poor repetition

Agrammatism

Effortful articulation, disrupted prosody

Phonemic paraphasias common

Lesion site: Frontal operculum, surrounding tissue, inferior frontal gyrus

Wernicke’s aphasia (wacky, fluent)

Characteristics:

Notable anomia

Poor auditory comprehension

Prosody WFL

Articulation WFL

Error types:

Phonemic, semantic, neologistic paraphasias

Empty content

May have jargon

Press of speech

Lesion site: Involves classic Wernicke’s area, posterior temporal gyrus, posterior section of middle and inferior temporal gyri

17
Q

Areas of cognitive impairment after a TBI include attention, __________, memory and __________, __________ processes, reasoning, as well as problem solving and ___________

A

Areas of cognitive impairment after a TBI include attention, perception, memory and learning, organizing processes, reasoning, as well as problem solving and judgement

18
Q

The main difference between frontotemporal dementias (FTD) and dementias of the alzheimers type (DAT) is that FTD patients retain ________, can keep track of ____ to ____ events and are still oriented in _______ and ________

Hallmark of FTD is gradual progressive decline in __________ and/or __________.

Vascular dementia is caused by inadequate bloodflow to the _______ and multiple _____’s

A

The main difference between frontotemporal dementias (FTD) and dementias of the alzheimers type (DAT) is that FTD patients retain memory, can keep track of day to day events and are still oriented in time and space

Hallmark of FTD is gradual progressive decline in behavior and/or language.

Vascular dementia is caused by inadequate bloodflow to the brain and multiple TIA’s

19
Q

Transcortical _______ Aphasia

Characteristics:

Impaired initiation of verbal _________

Anomia

________ phrase length

Good ____ comp

Good __________ in comparison to speech output

Unable to generate full __________

A

Transcortical Motor Aphasia

Characteristics:

Impaired initiation of verbal output

Anomia

Short phrase length

Good aud comp

Good repetition in comparison to speech output

Unable to generate full sentences

20
Q

________ aphasia

Characteristics:

Profound ________

Virtually no ________ output

Very _______ auditory comprehension

May have _____________ utterance (real word or nonsense syllables)

A

Global aphasia

Characteristics:

Profound anomia

Virtually no speech output

Very poor auditory comprehension

May have stereotypical utterance (real word or nonsense syllables)

21
Q

___________ aphasia

Characteristics:

Anomia

Fluent ________ with normal average phrase length (e.g. 9 words or more)

Speech may contain delays in word _________, self ___________

Auditory comprehension ______

Repetition worse than self ___________ speech

A

Conduction aphasia

Characteristics:

Anomia

Fluent output with normal average phrase length (e.g. 9 words or more)

Speech may contain delays in word finding, self corrections

Auditory comprehension good

Repetition worse than self formulated speech

22
Q

Transcortical _________ aphasia

Characteristics:

Severe ________

______ auditory comprehension

Relatively good __________ skills

Reduced flow of output due to anomia but preserved ___________ and prosody

Preserved grammar

________ content

E.g., “thing” for target word

____________ paraphasias more often than phonemic paraphasias

Perseveration common

A

Transcortical sensory aphasia

Characteristics:

Severe anomia

Poor auditory comprehension

Relatively good repetition skills

Reduced flow of output due to anomia but preserved articulation and prosody

Preserved grammar

Empty content

E.g., “thing” for target word

Semantic paraphasias more often than phonemic paraphasias

Perseveration common

23
Q

_________ aphasia

Characteristics:

Word _________ problems across tasks

Phrase length WNL

Delays for word ________

Aud comp and repetition relatively intact

Use of nonspecific terms, _____________

Paraphasias usually of __________ type

A

Anomic aphasia

Characteristics:

Word finding problems across tasks

Phrase length WNL

Delays for word retrieval

Aud comp and repetition relatively intact

Use of nonspecific terms, circumlocutions

Paraphasias usually of semantic type