Quiz 6

Question 1

Atenelol

Answer 1

Tenormin

Question 2

Lovastatin

Answer 2

Altoprev

Question 3

Lisinopril

Answer 3

Prinivil, Zestril

Question 4

Losartan

Answer 4

Cozaar

Question 5

Amlodipine

Answer 5

Norvasc

Question 6

Hydrochlorothiazide

Answer 6

various

Question 7

Candesartan

Answer 7

Atacand

Question 8

Indications: Angina pectoris, HTN, AMI

Answer 8

Atenolol

Question 9

Indications: Coronary arteriosclerosis; hypercholesteremia, primary and fixed; familial hypercholesteremia, heterozyogous

Answer 9

Lovastatin

Question 10

Indications: st-segment elevation, MI; HFrEF; HTN

Answer 10

Lisinopril

Question 11

Indications: HTN, Reduced risk of cerebrovascular accident, diabetic nephropathy

Answer 11

Losartan

Question 12

Indications: HTN; stable and variant angina

Answer 12

Amlodipine

Question 13

Indications: edema, HTN

Answer 13

Hydrochlorothiazide

Question 14

Indications: HF, HTN

Answer 14

Candesartan

Question 15

Interactions: NSAIDs, amiodarone, dronedarone, antidiabetics, CCBs, quinidine, clonidine

Answer 15

Atenolol

Question 16

Interactions: CYP3A4/5 inhibitors and inducers, fibrates, niacin

Answer 16

Lovastatin

Question 17

Interactions: ARBs, K-sparing diuretics, azathioprine, cyclosporine diuretics, NSAIDs, K-supplements, salt subs, sacubitril

Answer 17

Lisinopril

Question 18

Interactions: ACEIs, Diuretics, Aliskiren, CYP2CP and CYP3A4/5 inhibitors and inducers, K supplements, salt subs, NSAIDs

Answer 18

Losartan

Question 19

Interactions: CYP3A4/5 inhibitors and inducers, NSAIDs

Answer 19

Amlodipine

Question 20

Interactions: ace/arbs, antiarrhythmic agents, digoxin, antidiabetic meds, calcium supplements, carbamazepine, NSAIDs, Topiramate, lithium, dofetilide

Answer 20

Hydrochlorothiazide

Question 21

Interactions: Aldosterone antagonists, ACE, K supplements, NSAIDs, Diuretics

Answer 21

Candesartan

Question 22

Common AR: hypotension

Answer 22

Candesartan

Question 23

Common AR: hypotension, dizziness, headache

Answer 23

HCTZ

Question 24

Common AR: Peripheral Edema, PE

Answer 24

Amlodipine

Question 25

Common AR: headache

Answer 25

Losartan

Question 26

Common AR: n/a

Answer 26

Lisinopril and Lovastatin

Question 27

Common AR: Bradyarrhythmia, cold extremities, dizziness, fatigue, hypotension, depression

Answer 27

Atenolol

Question 28

RbS: HF, PE

Answer 28

Atenolol

Question 29

RbS: Rhabdomyolysis, hepatotoxicity, inc. risk of diabetes

Answer 29

Lovastatin

Question 30

RbS: angioedema, liver failure, birth defects

Answer 30

Lisinopril

Question 31

RbS: angioedema, birth defects, hepatotoxicity, rhabdomyolysis

Answer 31

Losartan

Question 32

RbS: hepatotoxicity, thrombocytopenia, AMI, angina

Answer 32

Amlodipine

Question 33

RbS: Cardiac arrhythmias, hepatitis, pancreatitis, SJ syndrome

Answer 33

HCTZ

Question 34

RbS: angioedema, birth defects, hepatotoxicity, rhabdomyolysis

Answer 34

Candesartan

Question 35

Efficacy: Dec. BP

Answer 35

All but statin

Question 36

Efficacy: reduction in chest pain, dec. number of weekly angina attacks, reduction in use of prophylactic nitroglycerin to relieve chest pain, improvement in s/s of HF

Answer 36

Atenelol

Question 37

Toxicity: s/s of HF, dec. HR. monitor serum electrolytes and renal function at baseline and periodically

Answer 37

Atenelol

Question 38

Counseling: Tk on empty stomach. Avoid abrupt discontinuation; exacerbations of angina may occur. Report s/s of bradycardia, hypotension, HF, or exacerbation of angina w/ initial dosing and dose changes. May cause dizziness or drowsiness. Diabetic pt. to carefully follow blood sugar lvls as beta-blockers may mask symptoms of hypoglycemia. Drug may cause sexual side effects, fatigue, and depression.

Answer 38

Atenelol

Question 39

Efficacy: Reduction in total cholesterol, LDL- cholesterol, and triglyceride levels; inc. in HDL-cholesterol levels. Assess at baseline and periodically during treatment

Answer 39

Lovastatin

Question 40

Toxicity: s/s of rhabdomyolysis or hepatotoxicity. LFTS, blood glucose, and HbA1C should be performed at baseline, 6-12 wk after initiation of therapy, and periodically thereafter; SCr kinase should be measured in pt. experiencing muscle pain and in those receiving other drugs associated w/ myopathy

Answer 40

Lovastatin

Question 41

Counseling: IR tablets should be taken w/ evening meal. ER tablets should be taken at bedtime and swallowed whole (don’t chew, crush, or cut). Avoid alcohol and grapefruit. Report s/s of rhabdomyolysis, jaundice, or renal failure. Lots of interactions. Consult PCP prior to starting any new prescriptions or OTC meds. Lovastatin does not take place of lifestyle changes to lower cholesterol levels.

Answer 41

Lovastatin

Question 42

Toxicity: s/s of angioedema, severe persistent cough, hypotension, monitor baseline and periodic electrolytes, SCr, BUN, and urine protein

Answer 42

Lisinopril

Question 43

Counseling: Avoid pregnancy. Use K supplements or salt substitutes only under medical supervision. May cause dizziness in women if dehydrated

Answer 43

Lisinopril

Question 44

Toxicity: s/s of peripheral edema. Baseline and periodic electrolyte panel, renal function tests, and urine protein are recommended

Answer 44

Losartan

Question 45

Counseling: avoid pregnancy. Avoid sudden discontinuation; rebound htn can occur. Use K supplement and salt subs under medical supervision. May cause dizziness and may worsen w/ dehydration. Seek medical attention if angioedema, excessive fluid loss, hyperkalemia, reduction in urination, or jaundice occurs

Answer 45

Losartan

Question 46

Efficacy: reduction in chest pain, dec. number of weekly angina attacks, reduction in use of prophylactic nitroglycerin to relieve chest pain, improvement in s/s of HF

Answer 46

amlodipine

Question 47

Toxicity: s/s of peripheral edema, inc. HR, LFTs

Answer 47

Amlodipine

Question 48

Counseling: Instruct pt. to report s/s of hypotension or exacerbation of angina w/ initial dosing or dose changes. Avoid alcohol. Report s/s of peripheral edema, fatigue, hypotension, or hepatic dysfunction. May cause dizziness. Avoid activities that could be dangerous if dizziness occurs at initiation of therapy. Dizziness may be worse if too much water is lost from the body due to excessive sweating, diarrhea, or vomiting.

Answer 48

Amlodipine

Question 49

Efficacy: reduction in edema

Answer 49

HCTZ

Question 50

Toxicity: Dec. serum and urine electrolytes (particularly serum sodium), dec. renal fuction, inc. serum uric acid or blood glucose. Seek medical attention if skin rash, jaundice, dec. urine output, or symptoms of gout. Dizziness, lighthededness may occur. Monitor Na, K, BUN, creatinine, skin to assess photosensitivity, skin cancer.

Answer 50

HCTZ

Question 51

Counseling: May be taken w/ or w/o food. Tk early to avoid nocturia, even if taken more than once/d. May cause dizziness. Report s/s of hypotension. Eat high-K foods during therapy. Avoid alcohol and NSAIDs

Answer 51

HCTZ

Question 52

Efficacy: resolution of HF; may require 3-6 wk to obtain therapeutic response

Answer 52

Candesartan

Question 53

Toxicity: Report s/s of hypotension, tachycardia. Baseline and periodic sodium, potassium, total bicarb, BUN, SCr, and urinalysis prior to initiating therapy.

Answer 53

Candesartan

Question 54

Counseling: Avoid pregnancy and notify physician immediately if become pregnant. Use K supplements or salt subs only under medical supervision. May cause dizziness that may worsen if dehydrated. Seek care if angioedema, excessive fluid loss, hyperkalemia, reduction in urination, or jaundice occurs

Answer 54

Candesartan