Quiz

Question 1

What are the 4C antibiotics that have increased risk of C.diff infection

Answer 1

Co-amoxiclav
Cephalosporins
Clindamycin
Ciprofloxacin (Quinolones)

Question 2

Which antibiotic causes photosensitivity as a side effect

Answer 2

doxycycline

Question 3

Which group of antibiotics lower the epileptic threshold

Answer 3

Quinolones

ciprofloxacin, moxifloxacin, ofloxacin

Question 4

Which quinolone is better for respiratory infection: ciprfloxacin or levofloxacin

Answer 4

Levofloxacin

Question 5

What cover does clarithromycin provide in CAP

Answer 5

it covers atypical organisms

Question 6

What antibiotic covers strep pneumoniae

Answer 6

amoxicillin

Question 7

Which antibiotic is not absorbed systemically

Answer 7

Vancomycin when given PO

Question 8

What are the side effects of quinolones

Answer 8

tendonitis
ruptured aortic aneurysms
seizures/psychiatric side effects
C.diff infection

Question 9

What is absorbed better, PO or IV quinolones

Answer 9

PO

Question 10

What is the alternative antibiotic to gentamicin

Answer 10

aztreonam

Question 11

Name a gram positive bacilli

Answer 11

Listeria monocytogenes

Question 12

Which antibiotics can cause deranged LFTs

Answer 12

Co-amoxiclav

Question 13

What group of people are associated with Salmonella infections

Answer 13

HIV

Sickle cell anaemia

Question 14

Tetracyclines can be given to all age groups, true or false

Answer 14

False, they should not be given to <12 because of permanent teeth staining

Question 15

Which antibiotic should never be used as a monotherapy

Answer 15

Rifampicin - bacteria can rapidly acquire resistance to it

Question 16

Which antibiotic does not cover Staph. A

Answer 16

penicillin

Question 17

In which condition are Koplik spots found

Answer 17

Measles

Question 18

Which bug causes “walking” pneumonia

Answer 18

Mycoplasma pneumoniae

Question 19

Which disease is transmitted via air when you sneeze

Answer 19

Measles

Question 20

Which bacteria can be contaminants in cultures

Answer 20

Staph. epidermidis

Diphtheroids

Question 21

If you have an allergy to penicillins, what part of the chemical are you allergic to

Answer 21

Beta lactam ring

Question 22

name the Beta lactam antibiotics

Answer 22

penicillin, amoxicillin, flucloxacillin...
Co-amoxiclav 
cephalosporins 
pipercillin-tazobactam 
carepenems

Question 23

Does penicillin cover streptococcus

Answer 23

yes, and nesseria meningitides and some anaerobes

Question 24

What does amoxicillin cover

Answer 24

enterococcus faecalis, strep, anaerobes and HiB

Question 25

Is co-amoxiclav broad spectrum

Answer 25

Yes, it covers Gm+, Gm- and anaerobes It also increases risk of C.diff infections It does not cover MRSA or coag-ve staph, pseudomonas, ESBLs or legionella

Question 26

Flucloxacillin is a broad spectrum antibiotic, true or false

Answer 26

False, it only covers staph and strep

Question 27

Give properties of clindamycin

Answer 27

It increases risk of C.diff infection It has anti toxin properties it covers MRSA, MSSA, strep and anaerobes

Question 28

What do the macrolides cover

Answer 28

atypical organisms in pneumonia

Question 29

Which antibiotics cover anaerobes

Answer 29

Metronidazole and clindamycin

Question 30

What does vancomycin cover

Answer 30

Gram +ves MRSA, MSSA, coag-ve staph, enterococci, strep, Clostridium

Question 31

Is co-trimoxazole a narrow spectrum antibiotic

Answer 31

No, it covers Gm+, Gm- and anaerobes

Question 32

What is gentamicin effective against

Answer 32

Gram negatives | Some synergistic effects against gram positives

Question 33

What does ciprofloxacin work against

Answer 33

Gram negatives

Question 34

What are the last resort antibiotics

Answer 34

Cerbepenems

Question 35

What are risk factors for getting a C.diff infection

Answer 35

Elderly, prolonged hospital stay, prophylactic antibiotics, PPIs, immunocompromised

Question 36

What is the treatment for non-severe C.diff

Answer 36

metronidazole PO

Question 37

What is the treatment for severe C.diff

Answer 37

PO vancomycin

Question 38

What makes gram negatives different from gram positives

Answer 38

They have a thinner peptidoglycan wall and an additional outer membrane they are harder to treat

Question 39

Does gentamicin have any anaerobic cover

Answer 39

No

Question 40

What classifies as a hospital acquired pneumonia

Answer 40

Stay in hospital >48 hours

Question 41

What covers Haemophilus influenzae

Answer 41

amoxicillin and doxycycline

Question 42

What are the atypical organisms in pneumonia and their treatment

Answer 42

Mycoplasma pneumoniae - macrolide Coxiella - Q fever - macrolide Chlamydophila psittici - macrolide Legionella - LEVOFLOXACIN

Question 43

What is used to treat pseudomonas

Answer 43

ciprofloxacin

Question 44

When a bug is an extended spectrum beta lactamase, which antibiotics is it resistant to

Answer 44

Penicillins, cephalosporins and aztreonam

Question 45

Which has better PO absorption, penicillin or amoxicillin

Answer 45

Amoxicillin