Quiz Review: 1, 2, 3, 4, 5, 6

Question 1

Beta 1 adrenergic receptors are linked to which G-protein:

Answer 1

-Gs

Question 2

Which is the following is the main mechanism of signal termination for norepinephrine:

Answer 2

Presynaptic reuptake

Question 3

Which medication has the highest risk of developing tachyarrhythmias?

Answer 3

-Epinephrine

Question 4

To reduce the risk of toxicity with nitroprusside, which medication may be added to the same bag for prevention:

Answer 4

-sodium thiosulfate

Question 5

Which medication is safest to reduce blood pressure for patients with coronary artery disease?

Answer 5

nitroglycerine

Question 6

-When deciding between phenylephrine and ephedrine for a pregnant patient, which parameter should be considered:

Answer 6

heart rate

Question 7

T/F: Vasopressin is always preferred over epinephrine due to improved effectiveness during cardiac arrest:

Answer 7

False

Question 8

Which medication has the highest risk of agitation or psychosis when given for an extended period of time

Answer 8

• ephedrine

- norepinephrine

Question 9

Hydralazine predominantly affects which part of the vasculature:

Answer 9

Dilates arteries to reduce afterload

Question 10

Which electrolyte is responsible for aiding in Norepinephrine release from its presynaptic vesicle?

Answer 10

Calcium

Question 11

What is the main mechanism of ephedrine tachyphylaxis?

Answer 11

-Reduced norepinephrine release

Question 12

Enalaprilat is responsible for blocking the enzyme responsible for which reaction:

Answer 12

Angiotensin1 to angiotensin 2

Question 13

Which of the following would be the least safe to give to a pregnant patient:

Answer 13

enalaprilat

Question 14

Midazolam is a CYP3A4 substrate. Diltiazem is a CYP3A4 inhibitor. What reaction may happen when given together:

Answer 14

Over sedation

Question 15

If dexmedetomidine is given as a rapid bolus, what cardiovascular side effects are possible:

Answer 15

-hypertension and bradycardia

Question 16

Which electrolyte needs to be monitored closely when a patient is taking an ACE inhibitor?

Answer 16

-Potassium

Question 17

Which pharmacokinetic parameter is responsible for esmolol’s short duration of action metabolim:

Answer 17

Metabolism

Question 18

Which beta blocker has the highest risk of side effects due to its extended mechanism of action?

Answer 18

Labetalol

Question 19

Which beta blocker could possibly exacerbate bronchospasms:

Answer 19

-Propranolol

Question 20

When organ damage is caused by accelerate hypertension, it is important to correct the blood pressure as quickly as possible to avoid further damage:

Answer 20

FALSE

Question 21

Which of the follwoing does not need to be tapered to avoid withdrawal symptoms:

Answer 21

Nicardipine

Question 22

Which of the following is the most potent negative inotrope?

Answer 22

Verapamil

Question 23

A patient experiencing clonidine withdrawal may have all of the following side effects except:

Answer 23

bradycardia

Question 24

Which electrolyte abnormality greatly increases the risk of developing digoxin toxicity:

Answer 24

hypokalemia

Question 25

Increasing heart rate puts a patient at risk of developing arrhythmias. which of the following has the highest risk of arrhythmia developement:

Answer 25

Isoproterenol

Question 26

Which lab value should be monitored closely after administration of a phosphodiesterase inhibitor:

Answer 26

Platelets

Question 27

Which type of arrhythmia is the most frequent cause of death from digoxin toxicity:

Answer 27

Ventricular fibrillation

Question 28

What may be present on EKG when a patient is taking digoxin to suggest digoxin therapy, not toxicity:

Answer 28

Swooping ST segment

Question 29

According to the ALARM-AF trial, the use of inotropes has the possibility of increasing in hispital mortality.

Answer 29

TRUE

Question 30

Which receptor does dobutamine not effect:

Answer 30

Dopamine

Question 31

Which medication mmay potentially depress the ventilatory response to hypoemia due to it's interaction with the carotid bodies:

Answer 31

Dopamine

Question 32

What is the general principle of the Frank Starling Curve:

Answer 32

Stroke volume increases with End diastolic Volume

Question 33

At high doses, which medication predominantly have alpha 1 effects:

Answer 33

- Norepinephrine - Dopamine - Epinephrine

Question 34

Phase 0 of the action potential is effected by which electrolyte AND which class of antiarrhythmic:

Answer 34

- Sodium | - Class1

Question 35

Reentry type arrhythmias are regulated predominantly by which electrolyte?

Answer 35

Sodium

Question 36

Torsades de Pointes (TdP) may be exacerbated by which electrolyte abnormality?

Answer 36

-Hypomagnesemia

Question 37

Which medication would be inappropriate for the treatment of atrial fibrillation?

Answer 37

-Lidocaine

Question 38

Which class of medication carries the highest proarrhythmic risk:

Answer 38

1c

Question 39

Lidocaine is classified as which type of antiarrhythmic:

Answer 39

1b

Question 40

A patient with Lupus should avoid which antiarrhytmic if possible, due to exacerbation of the condition?

Answer 40

Procainamide

Question 41

Adenosine produces an arrhythmia to stop an arrhythmia. What is seen on EKG after a dose of adenosine:

Answer 41

Third degree heart block

Question 42

Amiodarone has several significant side effects. Which of the following would not be caused by amiodarone?

Answer 42

Acute kidney failure and electrolyte abnormalities

Question 43

Verapamil will exacerbate an arrhythmia that has a re-entry mechanism?

Answer 43

True

Question 44

Which of the following medication may precipitate TdP?

Answer 44

Amiodarone

Question 45

Which adenosine receptor is primarily found in the cardiomyocytes:

Answer 45

A1

Question 46

Which of the following medications inhibits both bound and unbound clotting factors?

Answer 46

Alteplase

Question 47

Which ADP inhibitor only needs to be held 5 days prior to a procedure due to it's reversible mechanism of action:

Answer 47

-Ticagrelor

Question 48

Which clotting factor combines the intrinsic and extinsic pathways to inititae the common pathway, and is also a drug target for several medication s, including warfarin, heparin, and enoxaparin

Answer 48

Xa

Question 49

A pregnant patient with a DVT may use which medication:

Answer 49

Enoxaparin

Question 50

A patient with a history of heparin induced thrombocytopenia may safely use which medication in the future for anticoagulation:

Answer 50

Bivaludin

Question 51

Which new oral medication has a similar mechanism of action to argatroban?

Answer 51

-Dabigatran

Question 52

Which of the following medications has the longest hold time prior to surgery:

Answer 52

-Clopidogrel

Question 53

Heparin induced thrombocytopenia occurs how soon after initiation of the medciation in a heparin naive patient :

Answer 53

1 to 2 weeks

Question 54

Which of the following reaction is inhibited by amicar

Answer 54

Plasminogen to plasmin

Question 55

Which new anticoagulant has recommendation for discontinuation prior to surgery based on the patient's kidney function?

Answer 55

Dabigatran`

Question 56

Which clotting factors are inhibited by Warfarin

Answer 56

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