Quiz1 A-C Flashcards

1
Q

3MP

3-mercaptopropionic acid

A

Blocks GABA synthesis (anti GAD)

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2
Q

6-OH-DA

A

Kills DA and NE neurons

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3
Q

Allylglycine

A

Block GABA synthesis

Anti-pyridoxyl phosphate

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4
Q

Alphaxalone

A

Enhance GABA transmission

Via steroid site

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5
Q

Alprazolam

A

Enhances GABA-A

Benzodiazepine

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6
Q

Amitriptyline

A

Block NE and 5HT re-uptake

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7
Q

Amphetamine

A

Stimulates release of NE & DA

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8
Q

AMPT

Alpha-methylparatyrosine

A

Inhibit synthesis of NE and DA

Anti-hydroxylase

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9
Q

Atropine

A

Blocks postsynaptic mascarinic receptor

Belladonna - Galenical

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10
Q

Baclofen

A

Stimulates GABA-B receptors

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11
Q

Benzodiazepine

A

Enhance GABA-A transmission

Via BZ receptor

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12
Q

Benztropine

A

Block muscarinic receptor

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13
Q

Betacarbolines

A

Inverse BZ agonist

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14
Q

Bicuculline

A

Blocks muscarinic receptors

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15
Q

Black willow spider venom

A

Stimulates release of ACH

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16
Q

Botulinum Toxin

A

Inhibit ACh release

17
Q

Bromides

A

Sedatives
Anti-seizure drugs of 19th century
Mechanism unknown

18
Q

Buproprion

A

Block NE uptake?
Raise NE?

Antidepressant
Smoking cessation

19
Q

Buspirone

A

5HT 1-A partial agonist
5HT autoreceptors - Lower 5HT

Antidepressant

20
Q

Caffeine

A

blocks adenosine receptor

Coffee - galenical

21
Q

Cannabis

A

Stimulates anandamide receptors (CB1 and CB2)

Galenical

22
Q

Carbamazepine

A

Inhibit VGSC

Seizure
Neuropathic pain
Depression

23
Q

Chloral hydrate

A

GABA-enhancer

Old sedative / hypnotic
“Mickey Finn”

24
Q

Chlordiazepoxide

A

Enhances GABA-A transmission

Via BZ receptor

25
Q

Citalopram

A

SSRI

26
Q

Clobazam

A

Enhances GABA-A transmission

Via BZ receptor

27
Q

Clonazepam

A

Enhances GABA-A transmission

Via BZ receptor

28
Q

Clonidine

A

NE alpha2 autoreceptor Agonist

Inhibit NE release

29
Q

Cocaine

A

Block re-uptake of NE and DA