Rabies Flashcards

(47 cards)

1
Q

What type of organism is Rabies

A

Neurotropic viruses in the family Rhabdoviridae

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2
Q

Where does the rabies virus best replicate within the human body

A

The brain and nervous tissues

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3
Q

Two manifestations of rabies

A

Encephalitic “Furious”

Paralytic “Dumb”

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4
Q

Encephalitic presentation of rabies

A
  • Fever, hydrophobia, pharyngeal spasms, hyperactivity
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5
Q

Incubation period for rabies

A

1-3 months

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6
Q

What animal accounts for the majority of rabies inoculation

A

DOGS

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7
Q

Predisposing factors for contracting rabies

A

Veterinarians, wildlife researchers, exposure to bat colonies, feral/unvaccinated dogs & cats

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8
Q

What will rabies lead to because of the neurotropic nature of the virus

A

Encephalitis

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9
Q

How long is a captured animal observed in isolation for signs of infection or mortality

A

10-14 days

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10
Q

How many stools are needed to define diarrhea

A

3 or more loose or watery stools

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11
Q

Acute Diarrhea timeframe

A

< 14 days

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12
Q

Timeframe for persistent Diarrhea

A

More than 14-30 days

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13
Q

Timeframe for chronic diarrhea

A

> 30 days

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14
Q

What type of diarrhea presents with blood in loose-watery stools and fever
May be secondary to tissue damage to lining of the colon from certain bacteria, and/or toxins

A

Inflammatory Diarrhea

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15
Q

What type of diarrhea presents with watery stools with no blood and absence of fever

A

Non-inflammatory Diarrhea

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16
Q

Traveler’s diarrhea that is tolerable, not distressing, and does not interfere with planned activities

A

Mild Traveler’s diarrhea

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17
Q

Traveler’s diarrhea that is distressing or interferes with planned activities

A

Moderate Traveler’s diarrhea

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18
Q

Traveler’s diarrhea that is incapacitating or completely prevents planned activities

A

Severe Traveler’s diarrhea

Dysentery

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19
Q

What is the first line mitigation technique for infectious diarrhea

20
Q

bacteria that will cause diarrhea

A
  • Enterotoxigenic Escherichia ETEC
  • Campylobacter jejuni
  • Shigella ssp.
  • Salmonella ssp.
  • Bacterial toxin-releasing
21
Q

Viral etiologies that cause diarrhea

Almost never inflammatory

A
  • Norovirus

- Rotavirus

22
Q

Protozoal Etiologies that will cause diarrhea

A
  • Giardia

- Entamoeba histolytica

23
Q

What are routes that viral infectious diarrhea is spread

A

Fecal-oral route, direct contact with contaminated food& water, aerosols of vomitus, and contaminated environmental surfaces/objects

24
Q

Incubation period for viral infectious diarrhea

25
Norovirus Symptoms
- Acute onset of abdominal cramps, nausea, vomiting, and non-bloody diarrhea - body aches, headaches, and low-grade fever
26
What is the recommended treatment for viral diarrhea
Oral rehydration therapy, anti-motility agents, and antiemetics
27
are antibiotics recommended for treatment of diarrhea
Nope
28
When are antibiotics warranted for diarrhea
Severe diarrhea with high fever, manifestations of extraintestinal infections
29
What is the normal treatment for diarrhea caused by Camylobacter jejuni diarrhea
Generally self limiting and lasting < 1 week
30
What type of Protozoal parasite causes diarrhea
Giardia
31
Common name for Giardia diarrhea
Beaver Fever
32
What is the most common intestinal parasitic disease affecting humans in the United States
Giardia
33
Routes of transmission for giardia
Fecal-oral route, mammals (humans, beavers, dogs, and pets)
34
Life phases for giardia
Cyst form | Trophozoite form
35
which is the infectious form of Giardia Cyst form or Trophozoite form
Cyst form
36
What lab testing is available for the diagnosis for Giardias
Antigen detection assays - Use antibodies against cyst or trophozoite - Capable of detecting Giardia and Cryptosporidium Stool Microscopy -
37
Symptomatic presentation of acute Giardias
- Develop in 1-2 weeks - Diarrhea is foul smelling and greasy - Abdominal cramps - Bloating - Flatulence - Fatigue - Anorexia - Nausea
38
What is the treatment for Giardia
Tinidazole 2 mg PO single dose Metronidazole (Flagyl) 250 mg PO TID
38
What is the treatment for Giardia
Tinidazole 2 mg PO single dose Metronidazole (Flagyl) 250 mg PO TID
39
Characteristic symptoms of infectious diarrhea of the small bowel
``` Larger in volume Watery More abdominal cramping Bloating Gas ```
40
Characteristic symptoms of infectious diarrhea of the large bowel
``` More frequent Smaller volume More painful bloody stools Mucus ```
41
Physical findings of infectious diarrhea
``` +/- fever Mild Tachycardia and hypotension Dehydration Positive tilt, turgor, dry mucus membrane Increased bowel sounds Mild diffuse abdominal tenderness ```
42
What should be the initial treatment for infectious diarrhea
Rule out more serious / life-threatening pathologies
43
Diet for patients with infectious diarrhea
Bananas Rice Applesauce Toast
44
What is the dosage for loperimide (Imodium)
4 mg PO initially, followed y 2 mg PO after each loose stool. Not to exceed 16 mg/day
45
What is the dosage for Bismusth subsalicylate
525 mg Q 30-60 min PRN for up to 2 days, do not exceed 4200 mg/day
46
When should antibiotics be considered in the treatment of diarrhea
``` Fever + >10 stools/day + Significant or complete loss of operational effectiveness ```