RADBIO Flashcards

(36 cards)

1
Q

When is the advent of the age of the atomic bomb happen?

A

1940s

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2
Q

It is a mathematical
relationship between various radiation dose levels and
magnitude of the observed response.

A

Radiation dose-response relationship

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3
Q

Radiation dose response relationship have two important applications in radiology. First, these experimentally determined relationships are used to
design therapeutic treatment routines for _____

A

patients with cancer

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4
Q

Radiobiologic studies also have been designed to yield information on
the ______.

A

effects of low-dose irradiation

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5
Q

These studies and the dose response relationships revealed provide the basis for radiation
management activities and are particularly significant for_____

A

diagnostic radiology

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6
Q

Human responses to radiation exposure fall into two types:

A

Deterministic or Stochastic

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7
Q

Responses usually follow high-dose radiation exposure and appear as an early response

A

deterministic

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8
Q

deterministic exhibit a _____; there is a dose
below which no response occurs.

A

dose threshold

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9
Q

answer true or false.As radiation dose increases, the
severity of the response increases.

A

true

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10
Q

_____- skin burns
represent a deterministic response.

A

Radiation-induced

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11
Q

Stochastic Responses are______.

A

cancer, leukemia, or genetic effects

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12
Q

Such responses
usually follow low radiation exposure and appear as a late radiation
response years later

A

stochastic

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13
Q

In stochastic there is_____ and as radiation
dose increases, the frequency of response in a population increases.

A

no dose threshold

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14
Q

What are the two characteristic radiation dose-response relationship?

A

linear or nonlinear / threshold or nonthreshold

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15
Q

Answer with true or false: These
characteristics can be described mathematically or graphically

A

True

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16
Q

Threshold dose-response
relationship

A

deterministic

17
Q

Non-threshold dose-response
relationship

18
Q

Non-linear dose-response
relationship

A

deterministic

19
Q

Severity of response increases
with radiation dose

A

deterministic

20
Q

Linear dose-response
relationship

21
Q

Incidence of response
increases with radiation dose

22
Q

When the radiation dose is doubled, the
response to radiation likewise is __–

23
Q

Dose-response relationships A and B
intersect the dose axis at zero or below. These relationships are therefore the _____ type.

A

linear,
nonthreshold (LNT

24
Q

In a nonthreshold
dose-response relationship, any dose,
regardless of its size, is expected to produce
a response.. Answer with true or false

25
At zero dose, relationship A exhibits a measurable response, _--_
RN
26
The level RN, called the_____, indicates that even without radiation exposure, that type of response, such as cancer, occurs
natural response level
27
(Radiation-induced cancer, leukemia, and genetic effects follow a -____,___-_
linear, nonthreshold dose-response relationship.
28
All other radiation dose-response relationships are ____
nonlinear
29
Skin effects resulting from high-dose fluoroscopy follow a __-_
sigmoid-type dose response relationship.)
30
It is very difficult to determine the degree of response, even that of early effects, because the number of experimental animals that can be used is usually ___
small
31
The principal interest in diagnostic imaging is to estimate response at very low radiation doses. Because this cannot be done directly, we -___- the dose-response relationship from the high-dose, known region into the low-dose, unknown region
extrapolate
32
This extrapolation invariably results in a ____-
linear, non-threshold dose-response relationship
33
the natural incidence may be higher and there may be a ___
dose threshold.
34
At very ____ irradiated subjects experience less response than control participants.
low doses
35
Many radiation scientists today believe that the doseresponse relationship associated with medical radiation falls in between the____
LNT and hormesis
36
Regardless of our concern for low radiation doses to large populations, patient radiation dose___-- are totally acceptable considering the benefit to the patient
less than approximately 50 mSv