Radiation Biology Flashcards
(51 cards)
Depress circulating lymphocytes
0.25 Gy
Bone Marrow Acute Radiation Syndrome (dose and latent period)
> 2 Gy
1-6 weeks
GI Acute Radiaition Syndrome (dose and latent period)
> 8 Gy
5-7 days
CNS Acute Radiation Syndrome (dose and latent period)
> 20-50 Gy
4-6 hours
Nausea 30% of time
1 Gy
LD 50/30 (without/with treatment)
3-4 Gy without
8.5 Gy with
LD 50/60 (for bone marrow failure)
3-4 Gy
LD 50/4 (GI failure)
10 Gy
Fetal - first 2 weeks
50-100 mGy for fetal loss (all or nothing)
Fetal - 8-15 weeks
> 100-200 mGy reduced head diameter and mental retardation
30 IQ point drop per 1 Sv
with 1 Sv 40% chance retardation
Fetal - >15 weeks
less sensitive
Fetal - 3-8 weeks
> 250 mSv growth retardation
Increased risk childhood cancer (after week 9)
10-20 mSv
Fetal thyroid vulnerable
week 9 onward
Adult and child cancer risk (BEIR 5 and UNSCEAR)
8%/Sv, but with reduction factor 4-5%/Sv (1/10 if older than 50)
Up to 15%/Sv for child
Early transient erythema (dose and onset)
2 Gy
hours
Severe, robust, erythema (dose and onset)
6 Gy
1 week
Telangiectasia (dose and onset)
10 Gy
52 weeks
Dry desquamation (dose and onset)
13 Gy
4 weeks
Moist desquamation/ulceration (dose and onset)
18 Gy
4 weeks
Secondary ulceration (dose and onset)
24 Gy
>6 weeks
Temporary epilation (dose and onset)
3 Gy
21 days
Permanent epilation (dose and onset)
7 Gy
21 days
Annual lens dose rate limit
150 mSv (might become 20 mSv)
