Random

Question 1

3 stages of wound healing

Answer 1

inflammation, proliferation, tissue remodeling

Question 2

What does the matrix region contain

Answer 2

keratin producing cells

Question 3

what skin layer(s) does first degree burn go through

Answer 3

epidermis only

Question 4

second degree burn

Answer 4

epidermis and dermis

Question 5

what is the safest way to test for suspected peanut allergy in GP

Answer 5

IgE antibody testing

Question 6

what is the alternative milk of choice for infants with cow’s milk allergy

Answer 6

extensively hydrolysed infant formula milk

Question 7

what category of itch is scalp psoriasis

Answer 7

puritoceptive

Question 8

prurigo nodularis is a result of what

Answer 8

chronic itch

Question 9

type 2 hypersensitivity

Answer 9

direct cell killing

Question 10

type 3 hypersensitivity

Answer 10

immune complex mediated

Question 11

topical steroids are vasoconstrictive, true or false

Answer 11

true

Question 12

what synthesises collagen

Answer 12

fibroblasts

Question 13

what is porphyria cutanea tarda

Answer 13

painful, blistering skin lesions that develop on sunexposed skin

Question 14

topical steroids are lipophilic, true or false

Answer 14

true

Question 15

role of vitamin A

Answer 15

vital for epithelial proliferation, keratinisation and development

Question 16

role of vitamin k

Answer 16

essential for several blood coagulation factors

Question 17

role of vitamin C

Answer 17

essential co-factor in collagen formation e.g. hair, and for bone and teeth health

Question 18

role of zinc

Answer 18

required for many metabolic pathways. required for structure and function of skin. Vital for wound healing

Question 19

is rice gluten free

Answer 19

yes

Question 20

what vasoactive substances do mast cells release

Answer 20

histamine, tryptase, heparin (all preformed) and leukotrienes, prostaglandins, cytokines including IL4 and TNF (all synthesised on demand)

Question 21

serious features of anaphylaxis

Answer 21

throat swelling, wheeze, increased resp rate, tachycardia, hypotension

Question 22

cells of the innate immune response

Answer 22

monocytes/macrophages, neutrophils , dendritic cells, basophils, mast cells, eosinophils, NK cells

Question 23

which immune system responds rapidly

Answer 23

innate

Question 24

which immune system is slow response

Answer 24

adaptive

Question 25

which immune system has memory

Answer 25

adaptive

Question 26

side effects of vitamin d analogues

Answer 26

hypercalcaemia, hypercalcuria

Question 27

side effects of topical steroids

Answer 27

- thinning of skin - purpura - stretch marks - steroid rosacea - fixed telangiectasia - perioral dermatitis - may worsen or mask infections - systemic absorption (can cause adrenal suppression, cushing's syndrome). - rebound and cause flare in diseases like psoriasis - glaucoma and cataract.

Question 28

people with freckles have one defective copy of which gene?

Answer 28

MC1R

Question 29

actinic lentigines ("liver spots" or "age spots")

Answer 29

benign, small gray-brown spots on wrists, backs of the hands, forearms and face

Question 30

what is the medical name for common moles

Answer 30

melanocytic naevi

Question 31

What are actinic keratoses precursors of?

Answer 31

SCC

Question 32

what is subluxation?

Answer 32

partial dislocation, where the articular surfaces are displaced, but still overlap