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NAPLEX Prep > Random-ass Drugs > Flashcards

Random-ass Drugs Flashcards

(73 cards)

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1
Q

povidone-iodine (Betadine)

A

surgical hand scrub option if allergic to chlorhexidine

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2
Q

daprodustat (Jesduvroq)

A

oral ESA indicated for CKD patients who have been receiving dialysis for at least four months

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3
Q

adefovir (Hepsera)

A

nucleoside/tide reverse transcriptase inhibitor for hepatitis B

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4
Q

terlipressin (Terlivaz)

A

vasopressin analog for hepatorenal syndrome

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5
Q

cholera-PO (Vaxchora)

A

live-attenuated vaccine; caused by Vibrio cholerae and causes rice-water stools

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6
Q

typhoid-PO (Vivotif)

A

live-attenuated vaccine; caused by Salmonella typhi; spread by contaminated food/water

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7
Q

yellow fever-SC (YF-VAX)

A

live-attenuated vaccine; patient provided yellow card (ICVP) for country entry valid 10 days after date of vaccination

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8
Q

plazomicin (Zemdril)

A

last-line IV aminoglycoside for complicated UTI

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9
Q

tedizolid (Sivextro)

A

PO/IV oxazolidinone for SSTI

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10
Q

chloramphenicol

A

reversible 50-S binder with activity against Gram+/-/anaerobe/atypical; rarely used due to Aes (blood dyscrasias and Gray syndrome)

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11
Q

secnidazole (Solosec)

A

granule packet related to metronidazole

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12
Q

lefamulin (Xenleta)

A

first-in-class pleuromutilin that inhibits bacterial protein synthesis by binding to the 50S

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13
Q

omadacycline (Nuzyra)

A

approved for CAP

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14
Q

isavuconazonium (Cresemba)

A

prodrug of isavuconazole; requires a filter and causes QT shortening

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15
Q

anidulafungin (Eraxis)

A

echinocandin (inhibits beta (1,3)-D-glucan) injection for candidemia or esophageal candidiasis; no renal dose adjustment

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16
Q

oteseconazole (Vivjoa)

A

for recurrent vulvovaginal candidiasis

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17
Q

griseofulvin

A

for fungal infections of the skin, hair and nails

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18
Q

baloxavir marboxil (Xofluza)

A

endonuclease inhibitor for influenza treatment and prophylaxis (>5 years)

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19
Q

foscarnet (Foscavir)

A

injection for cytomegalovirus treatment; boxed warning for renal impairment

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20
Q

letermovir (Prevymis)

A

tablet/injection for cytomegalovirus prophylaxis

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21
Q

maraviroc (Selzentry)

A

blocks HIV from binding CD4 cells in virus strains that use the CCR6 co-receptor; requires tropism assay (does not work in CXCR4 or mixed co-receptors)

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22
Q

fostemsavir (Rukobia)

A

converts to temsavir which binds to the gp120 subunit of HIV envelope proteins inhibiting interaction between virus and CD4 host cell

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23
Q

ibalizumab-uiyk (Trogarzo)

A

moAb that binds to CD4 domain blocking viral entry

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24
Q

lenacapavir (Sunleca)

A

inhibits multiple stages of HIV life cycle (capsid inhibitor)

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25
bempedoic acid (Nexletol)
inhibits cholesterol synthesis in liver upstream of HMG-CoA
26
inclisiran (Leqvio)
inhibits production of PCSK9 via mRNA interference
27
lomitapide (Juxtapid)
prevents assembly of apoB-containing lipoproteins by inhibiting microsomal triglyceride transfer protein, REMS and as ajdunct for HoFH
28
evinacumab (Evkeeza)
moAb that inhibits angiopoietin-like 3 (ANGPLT3) resulting in increased lipid metabolism; as adjunct for HoFH
29
clevidipine (Cleviprex)
injection dihydropyridine CCB; CI soybean/egg allergy and emulsion provides 2 kcal/mL
30
vorapaxar (Zontivity)
for patients with history of MI or PAD to reduce thrombotic CV events
31
L-glutamine (Endari)
to reduce acute complications of sickle cell disease
32
voxelotor (Oxbryta)
inhibits hemoglobin S polymerization which prevents RBC sickling
33
netarsudil (Rhopressa)
Rho kinase inhibitor (increases aqueous humor outflow)
34
neomycin, colistin, hydrocortisone, and thonzonium (Corticosporin-TC)
for otitis externa
35
clascoterone (Winlevi)
topical androgen receptor inhibitor cream as alternative for mild acne treatment in 12+
36
crisaborole (Eucrisa)
topical phosphodiesterase-4 inhibitor for mild to moderate eczema
37
ruxolitinib (Opzelura)
topical Janus kinase inhibitor for mild to moderate eczema
38
selexipag (Uptravi)
tablet/IV infusion prostacyclin analog for PAH
39
pirfenidone (Esbriet)
for idiopathic pulmonary fibrosis
40
nintendanib (Ofev)
for idiopathic pulmonary fibrosis
41
zileuton (Zyflo)
tablet leukotriene formation inhibitor for asthma
42
omalizumab (Xolair)
IgG MoAb for severe asthma that inhibits IgE binding to mast cells and basophils
43
voclosporin (Lupkynis)
calcineurin inhibitor (prevents T-lymphocyte activation) for lupus
44
cladribine (Mavenclad)
oral anti-neoplastic
45
dalfampridine (Ampyra)
tablet potassium channel blocker to increase walking speed in MS
46
eculizumab (Soliris)
injectable complement inhibitor for treatment of MG; REMS for meningitis
47
lifitegrast (Xiidra)
ophthalmic treatment for dry eyes (Sjogren's); can cause dysgeusia
48
tapinarof (VTAMA)
topical cream for psoriasis treatment
49
deucravacitinib (Sotyktu)
tablet selective tyrosine kinase 2 inhibitor for systemic psoriasis treatment
50
romosuzumab (Evenity)
sclerostin inhibitor (blocks bone formation) for osteoporosis
51
prasterone (Intrarosa)
vaginally-inserted steroid for moderate-severe dyspareunia
52
ospemifene (Osphena)
oral estrogen agonist/antagonist for dyspareunia and moderate-severe vaginal dryness
53
fezolinetant (Veozah)
neurokinin B antagonist (works in thermoregulatory brain center) for vasomotor symptoms associated with menopause
54
flibanserin (Addyi)
tablet 5-HT1A agonist and 5-HT2A antagonist for hypoactive sexual desire disorder
55
bremelanotide (Vyleesi)
injection nonselective melanocortin receptor agonist for hypoactive sexual desire disorder
56
demeclocycline (Declomycin)
off-label for SIADH
57
aminocaproic acid (Amicar)
hemostatic agent
58
poractant alfa (Curosurf) or calfactant (Infrasurf)
for respiratory distress syndrome
59
nirsevimab (Beyfortus) or palivizumab (Synagis)
IM injection for respiratory syncytial virus infection prophylaxis; palivizumab is once monthly
60
nalmefene (Revex)
injection/oral spray for opioid overdose
61
lofexidine (Lucemyra)
tablet alpha-2 adrenergic agonist for mitigation of withdrawal symptoms
62
metaxalone (Skelaxin)
oral antispasmodic that exerts effect by sedation
63
canakinumab (Ilaris)
interleukin-1 antagonist for refractory gout
64
arsenic trioxide (Trisenox)
increases apoptosis of APL cells and damages the fusion protein promyelocytic leukemia-retinoic acid receptor alpha (PML-RARA)
65
fulvestrant (Faslodex)
IM injection selective estrogen receptor degrader
66
valbenazine (Ingrezza) or deutetrabenazine (Austedo)
reversibly inhibit VMAT2 for treatment of TD and chorea associated with Huntington's disease
67
tasimelteon (Hetlioz)
melatonin receptor agonist
68
safinamide (Xadago)
selective MAO-B inhibitor
69
cenobamate (Xcopri)
antiseizure medication; C-V
70
rufinamide (Banzel)
antiseizure medication; QT shortening
71
stiripentol (Diacomit)
antiseizure medication; taken with clobazam in Dravet's syndrome
72
vonoprazan (Voquezna)
oral potassium-competitive acid blocker for the treatment of erosive esophagitis
73
mirikizumab-mrkz (Omvoh)
interleukin receptor antagonist for ulcerative colitis

NAPLEX Prep (1 decks)

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