Random buzzwords

Question 1

Roth spots

Answer 1

Infective endocarditis

Question 2

Bamboo spine

Answer 2

Ankylosing spondylitis

Question 3

Pseudopallisading necrosis

Answer 3

Glioblastoma multiforme

Question 4

Prussian blue stain

Answer 4

Detects iron

Question 5

Orphan Annie cells

Answer 5

Papillary thyroid cancer

Question 6

Auer rods

Answer 6

AML

Question 7

Howell-Jolly bodies

Answer 7

Hyposplenism, megaloblastic anaemia

Question 8

Aschoff nodule

Answer 8

Rheumatic fever

Question 9

Lead pipe sign

Answer 9

Ulcerative colitis

Question 10

Heliotrope eyelids

Answer 10

Dermatomyositis

Question 11

Psammoma body

Answer 11

Papillary thyroid cancer, meningioma, mesothelioma

Question 12

Hypersegmented neutrophils

Answer 12

Megaloblastic anaemia (B12, folate)

Question 13

Froment’s sign

Answer 13

Ulnar nerve palsy

Question 14

Gottron’s papules

Answer 14

Dermatomyositis

Question 15

V/Q mismatch

Answer 15

Asthma, APO, chronic bronchitis

Question 16

Lupus pernio

Answer 16

Sarcoidosis

Question 17

Erythema nodosum

Answer 17

Sarcoidosis, IBD, TB, certain infections

Question 18

Pneumonia with long-intubation period (1-3wks)

Answer 18

Mycoplasma pneumoniae

Question 19

Ghon focus

Answer 19

TB

Question 20

Positive slipping sign

Answer 20

Lipoma

Question 21

Finkelstein’s test

Answer 21

De Quervain’s tenosynovitis

Question 22

Cobweb CSF

Answer 22

TB

Question 23

Shawl distribution of neuro symptoms

Answer 23

Central cord lesion/ compression

Question 24

Kimmelstiel-Wilson nodules

Answer 24

Diabetic nephropathy (nodular glomerulosclerosis)

Question 25

WBC casts in urine

Answer 25

Upper UTI (often pyelonephritis)

Question 26

'Starry sky' IgG deposits in kidney

Answer 26

Post-infectious GN

Question 27

Linear IgG deposits in kidney

Answer 27

Goodpasture's (Anti-GBM)

Question 28

"Tram-tracking" in kidney

Answer 28

MPGN

Question 29

"Spike & dome" in kidney

Answer 29

Membranous GN

Question 30

Effacement of foot processes

Answer 30

Minimal change GN, FSGS

Question 31

JAK-2 mutation

Answer 31

Polycythaemia rubra vera, Essential thrombocythaemia

Question 32

9-22 translocation

Answer 32

CML (Philadelphia chromosome, BCR-ABL), ALL (in adults)

Question 33

CAL-R mutation

Answer 33

Essential thrombocytosis

Question 34

Bence Jones proteins

Answer 34

MM

Question 35

"Starry sky" histology of lymphoma

Answer 35

Burkitt lymphoma

Question 36

Lacunar cells

Answer 36

Nodular sclerosis hodgkin lymphoma

Question 37

Translocation 8:14

Answer 37

Burkitt lymphoma

Question 38

C-myc activation

Answer 38

Burkitt lymphoma

Question 39

Translocation 14:28

Answer 39

Follicular lymphoma

Question 40

BCL-2 activation

Answer 40

Follicular lymphoma

Question 41

Translocation 11:14

Answer 41

Mantle cell lymphoma

Question 42

Over-expression of cyclin D1 protein

Answer 42

Mantle cell lymphoma

Question 43

Heinz bodies on New Methyl Blue staining

Answer 43

G6PD deficiency

Question 44

Erythroblasts (nucleus present in RBC)

Answer 44

Hypoxia, hemolysis, bone marrow infiltration, thalassemia, MPNs

Question 45

Basophillic stippling

Answer 45

Thalassemia, heavy metal poisoning, megaloblastic anaemia

Question 46

Sideroblasts

Answer 46

Sideroblastic anaemia

Question 47

Teardrop cells

Answer 47

Myelofibrosis

Question 48

Increased HbA2

Answer 48

Beta thalassemia minor

Question 49

Positive Ham's test

Answer 49

paroxysmal nocturnal haemoglobinuria

Question 50

Lymphoplasmacytoid bone marrow infiltrate

Answer 50

Waldenstrom macroglobulinaemia

Question 51

"Apple core" appearance on barium swallow

Answer 51

Oesophageal carcinoma

Question 52

"Leather bottle" stomach + signet rings

Answer 52

Gastric adenocarcinoma

Question 53

"Beading" of intra-hepatic ducts on ERCP

Answer 53

PSC

Question 54

Positive C-breath test (urea breath test)

Answer 54

Helicobacter pylori infection

Question 55

Anti-endomysial antibodies

Answer 55

Coeliac disease (IgA antibodies)

Question 56

IBD + eye symptoms

Answer 56

Anterior uveitis

Question 57

UC + skin ulcer

Answer 57

Pyoderma gangrenosum

Question 58

PHx small bowel resection + renal colic

Answer 58

Oxalate renal stones

Question 59

Anti-mitochondrial antibodies + pruitis

Answer 59

PBC

Question 60

Anti-smooth muscle antibodies + jaundice/liver dysfunction

Answer 60

Autoimmune hepatitis

Question 61

Kayser-Fleischer rings

Answer 61

Wilson's disease

Question 62

Drug SE: red secretions

Answer 62

Rifampicin

Question 63

Vitamin deficiency common in alcoholism

Answer 63

Thiamine (B1)