random pharm Flashcards
(19 cards)
enoxaparin
moa
LMWH; activate antithrombin
safe in pregnancy
atazanavir s.e.
hyperglycemia, lipodystrophy
Zidovudine s.e.
anemia
Isoproterenol moa
non selective beta agonist
253
increase heart contractility and decrease vascular resistance
Colchicine moa
blocks microtubule polymerization
stops nq’s from infiltrating a joint in GOUT
446
Flumazenil moa
blocks GABA A receptor
treatment for benzodiazepine overdose
497
Zolpidem moa
blocks GABA A - BZ1 subtype
this means: hypnotic with low addictive profile, no anesthesia, no seizure blocking effects.
better than benzo’s for sleep aid because non-addictive
Clozapine
side effect
agranulocytosis
important to monitor WBC’s in a patient with schizoid disorder taking clozapine
Fluconazole moa
inhibits ergosterol synthesis of fungi by inhibiting 14 alpha demethylase
used for candida and cryptococcus in AIDS
Methylphenidate moa
increase Norepinephrine and dopamine in cleft
use for ADHD
Fidoxamicin
use
recurrent c diff
griseofulvin mechanism inhibit b glucan synthesis for cell wall inhibit ergosterol synthesis for cell membrane inhibit microtubule function (mitosis) bind ergosterol making pores inhibit DNA precursor synthesis inhibit squalene epoxidase
microtubule function
flucytosine moa inhibit b glucan synthesis for cell wall inhibit ergosterol synthesis for cell membrane inhibit microtubule function (mitosis) bind ergosterol making pores inhibit DNA precursor synthesis inhibit squalene epoxidase
inhibit dna precursor synthesis
nystatin moa inhibit b glucan synthesis for cell wall inhibit ergosterol synthesis for cell membrane inhibit microtubule function (mitosis) bind ergosterol making pores inhibit DNA precursor synthesis inhibit squalene epoxidase
bind ergosterol - pores
amphotericin b moa inhibit b glucan synthesis for cell wall inhibit ergosterol synthesis for cell membrane inhibit microtubule function (mitosis) bind ergosterol making pores inhibit DNA precursor synthesis inhibit squalene epoxidase
bind ergosterol - pores
terbinafine moa inhibit b glucan synthesis for cell wall inhibit ergosterol synthesis for cell membrane inhibit microtubule function (mitosis) bind ergosterol making pores inhibit DNA precursor synthesis inhibit squalene epoxidase
bind squalene epoxidase
caspofungin moa (fungins) inhibit b glucan synthesis for cell wall inhibit ergosterol synthesis for cell membrane inhibit microtubule function (mitosis) bind ergosterol making pores inhibit DNA precursor synthesis inhibit squalene epoxidase
inhibit synthesis of beta glucan -> cell wall
itraconazole moa inhibit b glucan synthesis for cell wall inhibit ergosterol synthesis for cell membrane inhibit microtubule function (mitosis) bind ergosterol making pores inhibit DNA precursor synthesis inhibit squalene epoxidase
inhibit sterol (ergosterol) synthesis -> cells membrane
Alendronate moa
prevent bone resorption;
binds hydroxyappetite
bisphosphonate ; 445
