Rapid review Flashcards

1
Q

Abdominal pain, ascites, hepatomegaly

A

Budd-Chiari syndrome

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2
Q

Achilles tendon xanthoma

A

Familial hypercholesterolemia (decrease LDL receptor signaling)

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3
Q

Adrenal hemorrhage, hypotension, DIC

A

Waterhouse-Friderichsen syndrome (meningococcemia)

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4
Q

Athlete with polycythemia

A

Secondary to erythropoietin injection

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5
Q

Back pain, fever, night sweat, weight loss

A

Pott disease

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6
Q

Bilateral hilar adenopathy, uveitis

A

Sarcoidosis

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7
Q

Blue sclera

A

Osteogenesis imperfecta (type 1 collagen defect)

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8
Q

Bluish line on gingiva

A

Burton line (lead poisoning)

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9
Q

Bone pain, bone enlargement, arthritis

A

Paget disease of bone

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10
Q

Bounding pulse, diastolic heart murmur, head bobbing

A

Aortic regurgitation

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11
Q

Butterfly facial rash with Raynaud in young female

A

SLE

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12
Q

Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty, multiple endocrine abnormalities

A

McCune-Albright syndrome (mosaid G-protein signaling mutation)

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13
Q

Gowers sign

A

Child uses arm to stand up from squat seen in Duchenne muscular dystrophy

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14
Q

Chronic exercise intolerance with myalgia, fatigue, painful cramps, myoglobinuria

A

McArdle disease

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15
Q

Deep, labored breathing/hyperventilation

A

Kussmaul respiration seen in Diabetic ketoacidosis

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16
Q

Dilatd cardiomyopathy, edema, alcoholism or malnutrition

A

Wet beriberi (Thiamine deficiency)

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17
Q

Dysphagia, glossitis, iron deficiency anemia

A

Plummer-Vinson

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18
Q

Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells (2)

A
  1. Mycosis fungoides (cutaneous T-cell Lymphoma)
  2. Sézary syndrome (Mycosis fungoides + malignant T cells in blood)
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19
Q

Fever, chills, headache, myalgia follwing antibiotic treatment for syphilis

A

Jarisch-Herxheimer reaction

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20
Q

Fibrous plaques in soft tissue of penis

A

Peyronie disease

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21
Q

Hamartomatous GI polyps, hyperpigmentation of mouth/feet/hands

A

Peutz-Jeghers syndrome

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22
Q

Hepatosplenomegaly, osteoporosis, neurologic symptoms

A

Goucher (glucocerebrosidase deficiency)

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23
Q

Hereditary nephritis, sensorineural hearing loss, cataracts

A

Alpot syndrome

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24
Q

Male child, recurrent infections, no mature B cells

A

Bruton disease (x-linked agammaglobulinemia)

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25
Mucosal bleeding and prolonged BT
Glanzmann thrombasthenia (**defect in platelet aggregation due to lack of Gp2b/3a**)
26
Myopathy (**infantile hypertorphic cardiomyopathy**), exercise intolerance
Pompe
27
Nystagmus, intention tremor, scanning speech, bilateral internuclear ophthalmoplegia
MS
28
Palpable purpura on buttocks/legs, joint pain, abdominal pain, hematuria
Henoch-Schönlein purpura (**IgA vasculitis affecting skin and kidney**)
29
Pruritic, purple, polygonal planar papules and plaques
Lichen planus
30
Pupil accommodates but doesn't react
Argyll Robertson pupil due to **neurosyphilis**
31
Rapidly progressive leg weakness that ascends following GI/upper respiratory infection
Guillain-Barré
32
Rash on palms and soles (**3**)
1. Coxsackie A 2. Secondary syphilis 3. Rocky Mountain spotted fever
33
Anticentromere AB seen in
Scleroderma (**CREST**)
34
Antidesmoglein AB seen in
Pemphigus vulvaris
35
Antihistone AB seen in
Drug-induced SLE
36
Drugs causing SLE (**4**)
1. Hydralazine 2. INH 3. Phenytoin 4. Procainamide
37
Azurophilic peroxidase + granular inculsions in granulocytes and myelopblasts
Auer rods seen in AML
38
Bacitracin sensitive
S. pyogenes
39
Bacitracin resistant
S. agalactiae
40
Basophilic nuclear remnants in RBC
Howell-Jolly bodis seen in splenectomy or nonfunctional spleen
41
Basophilic stippling of RBCs seen in
Lead poisoning or sideroblastic anemia
42
Cardiomegaly with apical atrophy seen in
Chags disease (**Trypanosoma cruzi**)
43
Circular grouping of dark tumor cells surrounding pale neurofibrils
Homer-Wright rosettes
44
Homer-Wright rosettes seen in (**3**)
1. Neuroblastoma 2. Medulloblastoma 3. Retinoblastoma
45
Disarrayed granulosa cells in eosinophilic flud
Call-Exner bodes seen in granulosa-theca tumor
46
Eosinophilic cytoplasmic inculsion in liver cells
Mallory body seen in alcoholic liver
47
Intranuclear eosinophilic droplet-like bodies
Cowdry type A bodes in HSV or CMV
48
Large lysosomal vesicles in phagocytes, immunodeficiency seen in
Chédiak-Higashi disease
49
Novobiocin sensitive
S. epidermidis
50
Novobiocin resistant
S. saprophyticus
51
Onion skin periosteal reaction seen in
Ewing sarcoma (malignant round-cell tumor)
52
Optochin sensitive
S. pneumoniae
53
Optochin resistant
Viridan
54
Pseudopalisading tumor cells on brain biopsy
Glioblastoma multiforme
55
Absence seizure treatment
Ethosuximide
56
Acute gout treatment (**2**)
1. NSAIDs 2. Colchicine
57
ADHD treatment (**2**)
1. Methylphenidate 2. Amphetamines
58
Bipolar disorder treatment (**4**)
1. Lithium 2. Valproate 3. Carbamazepine 4. Lamotrigine
59
Breat cancer in postmenopausal women treatment
Aromatase inhibitor (**anastrozole**)
60
Candida treatment (**3**)
1. Amphotericin B (**systemic**) 2. Nystatin (**oral thrush**) 3. Azoles (**Vaginitis**)
61
Chronic gout treatment (**3**)
1. Probenecid 2. Allopurinol 3. Febuxostat
62
CML treatment
Imatinib
63
Chronic hepatitis treatment
IFN-α
64
Cryptococcus neoformans treatment
Fluconazole
65
Enterococci treatment
Vancomycin/ampicillin + AG
66
HER2/neu + breat cancer treatment
Trastuzumab
67
Hypertriglyceridemia treatment
Fibrate
68
Influenza treatment (**2**)
1. Rimantadine 2. Oseltamiver
69
Legionella treatment
Erythromycin
70
TB treatment ## Footnote **RIPE**
* **R**ifampin * **I**NH * **P**yrazinamide * **E**thanbutol
71
N. gonorrhoeae treatment
Ceftriazone
72
Ringworm infection treatment (**3**)
1. Terbinafine 2. Griseofulvin 3. Imidazole
73
SIADH treatment (**3**)
1. Demeclocycline 2. Lithium 3. Vasopressin receptor antagonists
74
Sporothrix treatment
Oral potassium iodide