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Cram Material > Rat Strains Quiz > Flashcards

Rat Strains Quiz Flashcards

1
Q

Diabetes insipidus

A

Brattleboro

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2
Q

Large granular lymphocytic leukemia

A

F-344

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3
Q

Intersitital cell tumor

A

F-344

(Leydig cell)

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4
Q

Corneal mineralization

A

F-344

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5
Q

Susceptible to E. cuniculi

A

Nude

(T-cell deficient - autosomal recessive)

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6
Q

Mega-small intestine

A

Ednrb

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7
Q

Seizures

A

Wistar

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8
Q

Polycystic Kidney Disease

A

Han:SRPD-cy

(autosomal dominant)

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9
Q

Pancreatic islet cell tumor

A

Sprague-Dawley

(more common females)

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10
Q

Hydronephrosis

A

Brown Norway (BN) - right kidney

Gunn - right kidney

Sprague-Dawley

also Wistar - certain strains

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11
Q

Control for hypertension rat

A

Wistar Kyoto (WKY)

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12
Q

Sensitive to Sendai

A

Brown Norway (BN)

Lewis (LEW)

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13
Q

Myeloma

A

LOU/C

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14
Q

Chronic myocardial disease

A

Sprague-Dawley

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15
Q

Diabetic Peripheral Motor Neuropathy

A

Wistar Bonn Kobori

(WBN/Kob)

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16
Q

Transverse vaginal septum

A

Wistar

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17
Q

Hirschprung’s Disease

A

Ednrb

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18
Q

Childhood absence epilepsy (petit mal)

A

Wag/Rij

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19
Q

Plasmacytomas

A

LOU/C

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20
Q

Spontaneous retinitis pigmentosa

A

eSS

WistarHanover (WH)

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21
Q

Autoimmune thyroiditis

A

Buffalo (BUF)

Lewis (autoimmune disease, not thyroiditis)

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22
Q

Inducible transplantable myeloid leukemia

A

Brown Norway (BN)

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23
Q

Polyarteritis Nodosa

A

Sprague-Dawley (SD)

SHR

Mendel Sherman MALES

24
Q

Intravascular hemolysis

A

Long-Evans Cinnamon

25
Lacks L-gulono-gamma-lactone oxidase
Osteogenic disorder Shionogi (ODS)
26
WIlson's Disease
Long Evan's Cinnamon (LEC) (mutation causing fulminant hepatitis by 4 months old - death within 1 week) Survivors develop hepatocellular carcinoma 1-1.5 years --\> WIlson's model
27
Bladder carcinoma
Brown Norway (BN) - males
28
Pituitary chromophobe adenomas (pars distalis)
Sprague-Dawley Wistar F-344 (most common in females) as well
29
Morris hepatoma
Buffalo (BUF)
30
Mononuclear cell leukemia
Wistar-Furth (WF)
31
Hypertension
SHR Fawn Hooded Dahl/Salt Sensitive
32
Eosinophilic granulomatous pulmonary inflammation
Brown Norway (BN)
33
Production if IgG autoantibody
LOU/C
34
Decreased serum thyroxine
Dwarf Rat
35
Aging
F-344 (gerontology)
36
Diabetes RESISTANT
BBDR/Wor Infect with Rat Parvo --\> autoimmune diabetes (increases expression of macrophage cytokines)
37
Multiple sclerosis
Lewis (LEW) Dark Agouti (DA)
38
Type II diabetes
BB Wistar Zucker Diabetic Fatty (ZDF) eSS
39
Nephrocalcinosis
F-344
40
Chronic Progressive Nephropathy
F-344 Sprague Dawley
41
Piebald
Ednrb
42
Obesity
Zucker (Lepr gene, fa mutation on chromosome 5 - autosomal recessive)
43
Juvenile insulin-dependent diabetes mellitus
BB/Wor
44
Resistant to chronic progressive nephropathy
Wistar Long-Evans
45
Prostatic adenocarcinomas
ACI Copenhagen (COP)
46
Auricular chondritis
Wistar
47
Crigler-Najjar Syndrome
Gunn
48
Hydrocephalus
Sprague-Dawley
49
Congenital genitourinary anomalies
ACI
50
Type 4 hyperlipoproteinemia
Obese SHR (autosomal recessive)
51
Hypochromic, microcytic anemia with abnormal iron metabolism
Belgrade (Nramp2 gene)
52
Jaundice, kernicterus
Gunn (autosomal recessive)
53
Resistant to Sendai (lesions less severe)
F-344
54
Low incidence of nephrocalcinosis
Sprague-Dawley Wistar
55
Congenital aganglionosis
Ednrb
56
High incidence mammary benign fibroadenomas
Sprague-Dawley (50%)
57
Megacolon
Ednrb

Cram Material (9 decks)

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